This section provides an overview for time-resolved spectroscopy as well as their applications and principles. Also, please take a look at the list of 7 time-resolved spectroscopy manufacturers and their company rankings. Here are the top-ranked time-resolved spectroscopy companies as of November, 2024: 1.Magnitude Instruments, 2.Bruker Corporation, 3.Hamamatsu Photonics K.K..
Table of Contents
In Time-Resolved spectroscopy, a chemical reaction is induced by irradiating a sample with a pulsed laser or instantaneously mixing two solution samples, and the changes resulting from the reaction are detected by emission and transmission (absorbance) spectroscopy. This technique is followed by a high-speed time-resolved measurement.
The measurement time range varies widely depending on the reaction of interest, ranging from femtoseconds (10 to the -15th power of seconds) to seconds.
The reaction initiation method, measurement principle, and instrument configuration also vary greatly depending on the measurement time.
In addition, depending on the wavelength region (energy region) in which the emitted or transmitted light is observed, the type and usage of light sources and detectors also vary.
Therefore, Time-Resolved spectroscopy products are designed specifically for one of the time and wavelength ranges.
Time-resolved spectroscopy is non-invasive because both the excitation and observation light are optical. With laser light as the light source, the light can travel a long distance. Therefore, the laser light source can be installed away from the main unit, or depending on the measurement device, a laboratory's existing laser light source, etc., can be used.
Most commercially available products use ultraviolet or visible light as the excitation light, and ultraviolet, visible, or near-infrared light as the observation light. However, it may be possible to build a system that uses an electron beam as the excitation light or infrared or synchrotron radiation as the observation light through customization.
In Time-Resolved spectroscopy, the products of chemical reactions often go through transient intermediates, and the identification of these intermediates provides a correct understanding of the reaction and, in turn, guidelines for improving the molecules used in the reaction. Intermediates can be estimated and identified from transient emission and absorption spectra.
The reaction rate is not only an indicator of the group of substances whose reactivity is to be compared, but also the time order of the reaction can be used to determine the type of reaction.
For example, there are intramolecular reactions and intermolecular reactions. For intermolecular reactions, various reaction parameters such as active energy or second-order rate constant can be determined from the temperature and concentration dependence of the rate.
In addition, by analyzing the spectral changes of multiple components in detail, the reaction mechanism can also be approached.
There are several types of Time-Resolved spectroscopy products, depending on the detection method and the time region of interest.
When a sample emits light, the luminescence lifetime is measured because the lifetime of the luminescence indicates the physical properties of the sample.
Luminescence is broadly classified into fluorescence in the nanosecond order and phosphorescence in the microsecond and millisecond order. Since there are different measurement techniques, there are devices that can measure both and devices dedicated to one or the other.
For samples whose transmittance (absorbance) changes at high speed due to pulsed light irradiation, etc., transient changes in the sample can be observed by using a light source to monitor the changes.
This method of Time-Resolved spectroscopy of transmitted light is also called the transient absorption method.
The femtosecond to picosecond method is called the pump-probe method, while the method for measurements slower than nanoseconds is called the flash photolysis method.
In the pump-probe method, a delay stage creates a time difference between the excitation light and the observed light, and the observed light is measured by a slow detector.
The flash photolysis method, on the other hand, uses a continuous light source and a high-speed detector.
In recent times, the RIPT method, which links these time ranges, is also becoming popular, but it employs a unique detection method.
Since the measurement technique differs greatly depending on the time range, it is necessary to select a device according to the time range of the target reaction. In most cases, a pulsed laser is used to induce a photoreaction.
Another fast time-resolved method is the stopped-flow method, in which two solutions are mixed to initiate a reaction, and millisecond changes are observed. In this case, a special mixing device is required to complete the mixing instantaneously.
General time-resolved measurements are macroscopic and require a uniform sample.
With luminescence lifetime devices, not only transparent solutions, but also suspended solutions, powders, and thin films can be measured as they are.
On the other hand, transient absorption systems, which measure transmitted light, generally measure transparent solutions and thin films with high transmittance. Some products can also measure shiny samples by direct reflection and powders by diffuse reflection.
Since sample temperature is also important in reaction rate measurements, a temperature-controlled unit is usually available.
Note that the presence of oxygen often affects the reaction rate and may require degassing by means of argon gas displacement or other methods.
*Including some distributors, etc.
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Bruker, founded in 1960 and based in Billerica, Massachusetts, is a manufacturer and distributor of scientific instruments and analytical and diagnostic solutions. The company's product range includes analyzers, microscopes, and imaging solutions, which have applications in fields such as life science research, cell biology, and microbiology. In 1969, the company developed the world's first FT-NMR spectrometer system, enabling broadband proton decoupling. In 1997, it further expanded its capabilities by acquiring the analytical X-ray division of Siemens AG. The company holds ISO 9001 and ISO 13485 certifications, and its products are available for sale worldwide.
Hamamatsu Photonics K.K., established in 1953 and headquartered in Hamamatsu, Japan, is a manufacturer of sensors and emitters for both visible and invisible light. It stocks products like LEDs, lamps, and photodiodes used in several industries, including consumer electronics, dental imaging, and environmental monitoring. The sensor and light source components are also available as modules and units that can be incorporated into systems the company develops, like optical measurement systems or imaging systems. The ISO 9001-certified company stocks over 15,000 devices, units, and systems that ship to over 100 destinations worldwide, and it has ten research and production bases.
HORIBA RADIO LABORATORY was established in Japan in 1945 and has spent the last three-quarters of a century growing as an R&D company and engaged in international operations. HORIBA Scientific offers 200 years of experience developing high-performance scientific instruments and analytical solutions. The HORIBA Group of worldwide companies provides an extensive array of instruments and systems for applications ranging from automotive R&D, process and environmental monitoring, in-vitro medical diagnostics, semiconductor manufacturing, and metrology to a broad range of scientific R&D and QC measurements. Operating in Asia, Europe, and North and South America, HORIBA scientific develops solutions that go beyond just products.
Photonic Solutions Ltd, founded In 1999 and based in Edinburgh, United Kingdom, is the independent distributor of photonics and associated technologies to the UK scientific and industrial market. It is a supplier to more than forty global manufacturers of optical components and laser systems. The company's wide range of products include, laser detectors, diagnostics and safety equipment, microscopes, spectrometers, custom-designed systems and related accessories. Its photonic products are backed up by unrivalled support and services.
Tokyo Instruments, Inc., established in 1981, and headquartered in Tokyo, Japan, is a manufacturer of opto-electronics products and systems. The company offers a wide range of products, including laser processing machines, aligning systems, photodetectors, analyzers for photoelectron spectroscopy, and spectroscopy array detectors. Also offered are high-speed, high-sensitivity cameras in UV to IR, and photon detectors or counters. The company's product families consist of the Nanofinder series of 3D Laser Raman Microspectroscopy systems and the iDus Workhorse laboratory and OEM CCD platform for low-light spectroscopy.
A&P Instruments, in China, is a supplier of laser and optoelectronics products. The company offers a wide range of laser diodes designed for precision and performance, suitable for applications in telecommunications, medical devices, industrial processes, and scientific research, election of optical components includes lenses, mirrors, prisms, and filters, providing critical elements for optical systems and experiments and a variety of optical instruments, including spectrometers, interferometers, and alignment tools for precision measurement and analysis.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Magnitude Instruments |
30.0%
|
2 | Bruker Corporation |
20.0%
|
3 | Hamamatsu Photonics K.K. |
20.0%
|
4 | A&P Instruments |
10.0%
|
5 | Photonic Solutions Ltd |
10.0%
|
6 | HORIBA |
10.0%
|
Derivation Method
The ranking is calculated based on the click share within the time-resolved spectroscopy page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 3 | 42.9% |
United States of America | 2 | 28.6% |
United Kingdom | 1 | 14.3% |
China | 1 | 14.3% |