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This section provides an overview for microplate readers as well as their applications and principles. Also, please take a look at the list of 17 microplate reader manufacturers and their company rankings. Here are the top-ranked microplate reader companies as of December, 2024: 1.Pope Scientific, Inc., 2.Labstac LLC., 3.Biochrom.
Table of Contents
A microplate reader is a laboratory device designed to simultaneously measure the absorbance or luminescence intensity of various samples placed in a microplate.
Depending on the microplate's well capacity, it can analyze dozens or even hundreds of samples at once, significantly enhancing laboratory efficiency. These instruments are pivotal in chemistry and biology research, particularly for quantifying proteins.
Despite their efficiency, it's crucial to acknowledge that microplate readers may be susceptible to errors when measuring minute quantities, emphasizing the importance of understanding their characteristics and limitations.
Microplate readers are instrumental in chemistry and biology for measuring absorbance in the ultraviolet and visible light spectrum for protein quantification and cell proliferation, as well as for assessing concentrations through luminescence or fluorescence reactions.
Historically, radioluminescence was a common method for concentration analysis, but advancements in luminescence substrates and fluorescent probes have shifted experimental techniques towards safer, non-radioactive methods.
These devices streamline the handling of numerous samples, reducing the workload on researchers. They are also versatile, allowing for sample pretreatment or monitoring absorbance changes over time, with many readers facilitating in-situ reactions and subsequent measurements.
Microplate readers operate on principles of absorbance and fluorescence measurement, each requiring monochromatic light, achieved via optical filters or monochromators for wavelength selection.
Absorbance is assessed by directing light of a specific wavelength through a sample in the microplate and measuring the transmitted light's intensity. Absorbance, proportional to concentration according to the Beer-Lambert law, allows for concentration determination by comparison with a known calibration curve. However, measurements can be compromised by microplate damage, contamination, or air bubbles within the sample.
This method measures the intensity of fluorescence emitted by a sample upon excitation by light of a specific wavelength. The fluorescent materials absorb this light, become excited, and then release energy as they return to their ground state, emitting detectable light proportional to concentration. This specificity provides high sensitivity and accuracy in measurements.
Choosing the right microplate reader depends on the intended measurement method, including absorbance, luminescence, or fluorescence. Multi-mode readers capable of switching between different measurement principles are also available.
It's essential to consider the light source's wavelength range and the settable measurement wavelengths to ensure compatibility with your experiments. Additionally, the available measurement and analysis options, along with the software's functionality, should align with your research needs, particularly for applications like enzyme kinetics or frequent quantification tasks.
*Including some distributors, etc.
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Promega Corporation, founded in 1978 and headquartered in Madison, Wisconsin, operates as a manufacturer of enzymes and products catering to biotechnology and molecular biology. Its extensive product range covers genomics, protein analysis, cellular analysis, drug discovery, and genetic identity products, which are utilized in various fields of scientific research. Additionally, the company offers custom solutions, including a wide range of capabilities in manufacturing, technology development, assay automation, and inventory management. The company has obtained certification to international standards for quality management systems in 1998.
Labstac LLC, founded in 2012, is a manufacturer and supplier of laboratory, scientific, and medical equipment headquartered in Pittsfield, MA, USA. The company operates in over 34 countries with an extensive distributor network covering American, European, the Gulf, and South Asian regions. The company's product lineup includes biosafety cabinets, centrifuges, incubators, autoclaves, and various other medical laboratory supplies. With an annual turnover of $50K USD, the company specializes in both buying and selling as a Limited Liability Partnership. The company's products are used in the pharmaceutical and medical industries as well as in biotechnology, hospitals, and research centers.
Thermo Fisher Scientific Inc., founded in 1956 and headquartered in Waltham, Massachusetts, is a manufacturer and supplier of life science solutions, analytical instruments, specialty diagnostics, laboratory products, and biopharma services. Through its brand names, including Invitrogen, Fisher Scientific, Patheon, Applied Biosystems, and Gibco, among others, the company provides a wide range of products, which include chromatography systems, thermal cyclers, automated cell counters, fermenters, and DNA polymerases. The company’s annual revenue is over 40 billion USD, and it serves several fields, including customers working in clinical diagnostic labs, research institutions, hospitals, government agencies, and pharmaceutical/biotech companies.
Narang Medical Limited, established in Delhi, in 1989 is a manufacturer of medical Equipment, Hospital Furniture, Orthopedic Implants, and Instruments. Their product portfolio includes infusion pumps, anesthesia machines, defibrillators, and diagnostic devices used in various medical settings. The company products find application in Hospitals and Medical Centers, Clinics and Healthcare Facilities, Orthopedic Centers and Hospitals, and Ambulatory Surgical Centers. The company exports its products to over 80 countries including the USA and the Middle East.
BIOBASE GROUP is a Chinese manufacturer of medical and laboratory equipment founded in 1999 and headquartered in Jinan, Shandong. The company offers over 200 different products including laboratory and medical cryogenic equipment, clinical analytical instruments, air protection devices, and specialized storage products. It also produces various medical consumables such as gloves, masks, and syringes. Biobase Group has branches in the US, India, Dubai, Singapore, and Kazakhstan. It offers global distribution and additional customization services to its clients in the biotechnology, environmental, cosmetic, and educational sectors.
Biochrom, founded in 1970, is based in Cambridge, United Kingdom, and is a manufacturer of scientific instruments and equipment for life science research. The company manufactures a diverse range of products, including spectrophotometers, microplate readers, and amino acid analyzers. These instruments offer precise measurements, advanced data analysis, and compatibility with various sample types, assisting in accurate and efficient research outcomes. Industries such as biotechnology, pharmaceuticals, and academic research utilize the products to analyze DNA, proteins, and other biomolecules.The user-friendly interface and genuine results offered by the products makes it convenient for researchers to come up with optimal data.
BMG LABTECH, founded in 1989 and headquartered in Ortenberg, Baden-Wuerttemberg, is a manufacturer and distributor of microplate reader instrumentation. The company's product range includes Microplate Readers, Plate Readers, Luminometers, Fluorometers, and Absorbance Readers. These products are widely used in basic research analysis and high-throughput screening. They primarily serve the pharmaceutical, biotechnology, academic research, and biotech research establishments industries. Additionally, it offers services such as microplate reader technology development, personalized customer support, application-specific guidance, and a comprehensive support network to ensure optimal instrument performance.
Berthold Technologies was founded in 1949 by Dr. Rudolf Berthold, located in Oak Ridge, Tennessee, and is a developer and manufacturer of measuring solutions. The company develops measurement technologies including level measurement, density measurement, bulk flow measurement, online moisture measurement, concentration measurement, and sources and shields. It's products find applications in a wide range of industries, including refineries, oil and gas, chemical and petrochemical, sugar, pulp and paper, food and beverages, building and construction, mining and mineral processing, water and recycling, and power generation. The company holds ISO9001 and ISO14001 certificates,
Hidex is a manufacturer of scientific analysis equipment established in 1993 and based in Turku, Finland. The company offers microplate readers for life science applications, and liquid scintillation as well as gamma counters for measuring radioactivity. It also offers radiochemistry equipment for positron emission tomography (PET) and related applications, such as tracer solutions, intravenous line, and lead aprons. The company’s products are used in the laboratory, research and development, and life sciences sectors.
Hinds Instruments, Inc. is a manufacturer of polarization-based measurement instruments, founded in 1971 and based in Portland, Oregon, United States. The company initiated the commercialization of photoelastic modulators (PEMs) and has since expanded its product line to include various PEM products. These include point and scanning birefringence measurement systems and polarization imaging systems under the Exicor brand. It also offers Mueller polarimeters, PolSNAP waveplate-based Stokes polarimeters and related accessories. The company further manufactures the EKKO series of CD MicroPlate Readers for direct circular dichroism measurement from standard wellplates.
Photon etc., founded in 2003 and based in Montréal, Canada, is a manufacturer specializing in hyperspectral and infrared imaging systems. The company provides science-grade infrared cameras and lenses, macro and microscopic hyperspectral imaging systems, and spectrometers. It also offers a range of tunable filters and laser sources. These products are used to enhance semiconductor materials as well as activity-based sensors and biomarkers in life sciences. They are also utilized in industrial settings for textile sorting, mineralogy mapping, and microplastic monitoring in water bodies.
Inovia Technology is a manufacturer of laboratory consumables and equipment established in 2012 and located in Esenler, Istanbul, Turkey. The company primarily offers consumables, reagents, and kits for syndromic testing and genetic disease research. It also offers PCR devices for DNA or RNA testing, centrifuges for sample separation, and nucleic acid separation systems for molecular biology analysis processes. The company is ISO 9001:2008 and TSE-certified, and mainly serves the biotech industry as well as clients in laboratory research operations.
Pope Scientific, Inc. is a manufacturer of chemical processing and laboratory equipment founded in 1963 and located in Saukville, Wisconsin, USA. The company’s products include fractional distillation systems for purification or separation processes using packed column technology, and short path stills and evaporators for distillation of temperature sensitive solutions or materials. It also offers hybrid fractional distillation systems utilizing multi-plate technology and low temperature reboiling. The company mainly serves clients in the chemical processing, pharmaceuticals, and laboratory industries.
Huanghua Faithful Instrument Co.,LTD is a manufacturer and supplier of laboratory equipment and medical equipment. The company was founded in 2011 and is based in coastal city-Huanghua The company offers a comprehensive range of products which include laboratory balances, spectrophotometers, centrifuges, and more. The company products have been extensively used in domestic and foreign research institutes and university laboratories. The company is aimed at providing tailored solutions to meet diverse needs across research, healthcare, manufacturing, and education sectors.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Pope Scientific, Inc. |
13.4%
|
| 2 | Labstac LLC. |
9.4%
|
| 3 | Biochrom |
8.9%
|
| 4 | Byonoy Gmbh |
6.8%
|
| 5 | Promega Corporation |
6.5%
|
| 6 | BMG LABTECH |
6.5%
|
| 7 | INOVIA TECHNOLOGY |
6.0%
|
| 8 | Hinds Instruments, Inc. |
6.0%
|
| 9 | Photon etc. |
6.0%
|
| 10 | Perlong Medical Equipment Co., Ltd. |
4.7%
|
Derivation Method
The ranking is calculated based on the click share within the microplate reader page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
3 | 23.1% |
|
China
|
3 | 23.1% |
|
Germany
|
3 | 23.1% |
|
India
|
2 | 15.4% |
|
United Kingdom
|
1 | 7.7% |
|
Finland
|
1 | 7.7% |
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