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This section provides an overview for cell analyses as well as their applications and principles. Also, please take a look at the list of 7 cell analysis manufacturers and their company rankings. Here are the top-ranked cell analysis companies as of December, 2024: 1.Roche CustomBiotech, 2.Biocompare, 3.MilliporeSigma.
Table of Contents
Cell analysis encompasses various techniques and equipment, tailored to specific aspects of cells one wishes to study. These methods can range from simple imaging to complex molecular analysis.
Common imaging uses a microscope or camera to assess cell number, condition, and viability. Advances in AI have led to software capable of automating cell count and long-term observation.
Instrumentation advancements in cell analysis have enabled detailed studies of cell behaviors such as migration, division, proliferation, and morphological changes, contributing significantly to recent breakthroughs in cell biology.
Cell analysis is integral to various fields including clinical research, reproductive medicine, and drug development. Its role is particularly crucial in cancer research due to the complexities of cancer cell behaviors like expression, migration, and network formation.
Diverse methods, like fluorescence microscopes, are employed in cell analysis, each selected based on the research goal. Recent developments include automated cell counting devices, enhancing accuracy and consistency in research.
Cell analysis often relies on imaging techniques, with fluorescence microscopy being a prominent method. It uses fluorescence emitted from a sample under specific wavelengths to capture images.
When exposed to intense light, molecules in the sample emit fluorescence of different wavelengths, allowing for substance-specific analysis. Overlaying images of various substances offers a comprehensive view of cellular states.
For instance, imaging cells stained for the cytoskeleton and mitochondria during mitosis provides vivid and detailed visualizations.
1. Microscopy/Imaging Analysis:
Microscopes and cameras with broad wavelength capabilities, including visible light and near-infrared, enable detailed observation of cell morphology and changes. Some systems allow long-term live cell observation in conditions like those in an incubator.
Modern devices also quantify cell number and morphology through image analysis software.
2. Flow Cytometer:
Flow cytometers measure cell count and characteristics using laser beams and fluorescence. They are essential in diagnosing conditions like leukemia and for analyzing cell clusters.
3. Cell Analyzer:
A specialized flow cytometer, it counts cells on a slide, including challenging cell types like peripheral blood mononuclear cells, without sample collection.
4. Plate Reader:
This instrument assesses cell proliferation and viability by measuring absorbance and fluorescence.
5. Gene Transfer Device/Cell Fusion Device:
Used in plant breeding and gene therapy research, these devices enable gene introduction and cell fusion.
*Including some distributors, etc.
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Beckman Coulter, Inc. is a manufacturer of scientific research instruments primarily for the academia and pharmaceutical markets. The company is a merger between Beckman Instruments, Inc. and Coulter Corporation based in Indiana, United States with a history dating back to 1935. Beckman Coulter develops and manufactures instruments for the clinical research market, and applied markets including food and beverages, agriculture, oil and gas, and aerospace. The company's range of instrument and reagents include Air and Liquid Particle Counters, Centrifuges, and Genomic Solutions.
Yokogawa Test & Measurement Corporation was founded in Japan in 1954. Yokogawa currently serves a wide array of industries including the aerospace, automotive, consumer electronics, semiconductor and telecommunications industries with both hardware and software solutions. Among Yokogawa’s suite of products are oscilloscopes, voltage probes, power analyzers and meters, data acquisition tools, optical test equipment, a wide variety of handled meters, calibrators, and testers; analog instruments, and manometers.
Sartorius AG, started in 1870 and headquartered in Göttingen, Germany, is a manufacturer and supplier of lab products and bioprocess solutions. It is the parent company of the Sartorius Group and provides instruments, consumables, and services for chemical, biopharmaceutical, and academic set-ups. The company sells its products under several brand names, such as Cubis, Ambr, and Flexsafe, and provides services like bioprocess consulting, biologics testing, and instrument service. It is available in over 60 countries and is listed on the Frankfurt Stock Exchange with preference and ordinary shares. It operates two divisions, namely bioprocess solutions and lab products and services.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Evident Corporation is a scientific research and development company in Shinjuku, Tokyo that was established in 2008. Formerly known as Olympus Scientific Solutions, the company specializes in developing cutting-edge technology and products for various industries, including aerospace, automotive, electronics, energy, and medical research. Evident Corporation has proliferated and expanded its product offerings and services to meet the needs of its customers. Their product offerings include non-destructive testing (NDT) solutions such as thickness gauges and automated inspection systems, XRF analyzers like handheld XRF analyzers, industrial microscopes, and video scopes and borescopes.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Roche CustomBiotech |
20.0%
|
| 2 | Biocompare |
20.0%
|
| 3 | MilliporeSigma |
20.0%
|
| 4 | Sartorius AG |
20.0%
|
| 5 | Beckman Coulter, Inc. |
10.0%
|
| 6 | Yokogawa Test & Measurement Corporation |
10.0%
|
Derivation Method
The ranking is calculated based on the click share within the cell analysis page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
2 | 50.0% |
|
Japan
|
2 | 50.0% |
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