This section provides an overview for cell sorters as well as their applications and principles. Also, please take a look at the list of 10 cell sorter manufacturers and their company rankings. Here are the top-ranked Cell Sorters companies as of March, 2023: 1.Cytonome/ST, LLC
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A cell sorter is a device used to isolate specific cells. In recent years, single-cell analysis, in which biological phenomena are observed at the level of a single cell, has become increasingly important in biological research.
Flow cytometry is a representative technology for high-throughput analysis of individual cells, and cell sorter is used to separate and collect cells. A cell sorter, like flow cytometers, allows cells labeled with a specific marker to flow through a tube. Only a specific population of cells can be aseptically sorted into a separate tube. The separated and collected cells can then be cultured for further analysis.
Cell sorters are used in a variety of fields, including cancer research, genetics, immunology, and culture engineering. Recently, the technology has also been applied in the medical field. For example, attempts are being made to use cell sorters to extract hematopoietic stem cells alone and transplant them into patients with leukemia.
In the field of regenerative medicine, plans are underway to induce differentiation of necessary cells in vitro from pluripotent stem cells, such as ES cells and iPS cells, and to use them for transplantation therapy and drug development. In this case, too, it is important to collect only the target cells, and cell sorters technology is being used to isolate and collect specific cells.
The first step in the cell sorter process is to pass the cell suspension through a very thin tube and separate the cells one by one. At this point, the cells are designed to flow from top to bottom, and the cells fall as droplets from the tip of the nozzle. Next, the falling cells are irradiated with laser light and the scattered light from them is analyzed to read the characteristics of each individual cell. The instrument instantly determines whether the cells should be separated or not. When a cell to be separated is detected, the droplet containing that cell is given a + or - charge. The charged droplet then falls between two subsequent polarizers. Droplets with a + charge are attracted to the negative plate and droplets with a - charge are attracted to the positive plate and collected in the test tubes placed under each plate. Uncharged droplets fall vertically and are usually discarded. Some instruments use microplates as collection vessels, and cells can be aliquoted into each well of the plate.
*Including some distributors, etc.
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Ranking as of March 2023 in United States of America
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Cytonome/ST, LLC | 100% |
Ranking as of March 2023 Globally
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Cytonome/ST, LLC | 100% |
Derivation Method
The ranking is calculated based on the click share within the cell sorter page as of March 2023. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
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