10 Nucleic Acid Extraction System Manufacturers in 2023
This section provides an overview for nucleic acid extraction systems as well as their applications and principles. Also, please take a look at the list of 10 nucleic acid extraction system manufacturers and their company rankings.
Table of Contents
What Is a Nucleic Acid Extraction System?
Nucleic acids are DNA and RNA used to elucidate the genetic system.
Nucleic acids from animals and plants are used to elucidate the genetic system and in the pursuit of the causes of diseases and genome research.
For this purpose, it is necessary to extract nucleic acids from the blood and tissues of animals and plants.
There are many extraction methods for nucleic acids. Still, the phenol/chloroform method, which has been used for a long time, is challenging to handle reagents, and fluid waste disposal is also tricky.
However, even with extraction kits, a significant amount of time and labor are required to process many samples, so a nucleic acid extraction system was developed to automate the operation.
Nucleic acid extraction systems are used in medical institutions and for research because they automatically process a large number of samples once the samples, the reagents, and cartridges included in the dedicated kits are set in the main unit.
There are various types of nucleic acid extraction systems.
The type of nucleic acid that can be processed, the number of samples, and the extraction time differ, so it is recommended that you select the one that best suits your purpose.
Uses of Nucleic Acid Extraction Systems
Because it can process many samples quickly, nucleic acid extractors are used in institutions and laboratories undertaking genetic testing.
In the case of the influenza virus and RS virus, all medical institutions are equipped with simple diagnostic kits, and PCR (Polymerase Chain Reaction) testing is unnecessary.
However, for coronavirus Covid-19, few reliable and straightforward diagnostic kits have yet been developed.
Therefore, it is necessary to extract the RNA of the virus to perform a PCR test on the patient.
This Nucleic acid extraction system can extract from a few to 96 samples in a short time, around 60 minutes, depending on the model.
Sample volumes that can be processed range from 100 µL to 5 mL.
Principle of Nucleic Acid Extraction Systems
There are various extraction methods for nucleic acids. Still, the current method is to adsorb DNA or RNA onto an anion exchange resin or silica membrane filter and elute them by adjusting the salt concentration and pH.
The dedicated extraction kits sold by QIAGEN use this principle.
This Nucleic acid extraction system uses the silica membrane method. It can automatically purify plasmid DNA, genomic DNA, viral nucleic acids, RNA, and proteins by changing the corresponding kits and protocols.
The system is equipped with centrifugation, heating, shaking, and pipetting functions, and extraction is performed using a robotic arm.
First, the sample is dissolved and adsorbed on a spin column with a silica membrane.
Next, the silica membrane filter is washed with the kit's reagents, and the target nucleic acids are eluted.
There is no carry-over, and the load check function confirms that the sample, reagents, tubes, etc., are set up correctly.
The type of nucleic acids that can be processed, the number of samples, and the extraction time vary depending on the model.
The QIAGEN nucleic acid extraction system can extract DNA from 100 bp to 10 kbp.
Other manufacturers such as Hitachi, Thermo Fisher, PerkinElmer, and others also sell their products.
List of 10 Nucleic Acid Extraction System Manufacturers
*Including some distributors, etc.
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QIAGEN
DNA & RNA Purification
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Nucleic Acid Extraction System Manufacturer Ranking
*Including some distributors, etc.Ranking as of March 2023 in United States of America
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Advanced Biological Laboratories (ABL), S.A. | 14.3% |
| 2 | Geneaid Biotech Ltd. | 14.3% |
| 3 | Daan Gene Co., Ltd. | 14.3% |
| 4 | ACON Laboratories, Inc. | 14.3% |
| 5 | QIAGEN | 14.3% |
| 6 | NTL Biotech | 14.3% |
| 7 | PerkinElmer Inc. | 14.3% |
Ranking as of March 2023 Globally
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Advanced Biological Laboratories (ABL), S.A. | 14.3% |
| 2 | Geneaid Biotech Ltd. | 14.3% |
| 3 | Daan Gene Co., Ltd. | 14.3% |
| 4 | ACON Laboratories, Inc. | 14.3% |
| 5 | QIAGEN | 14.3% |
| 6 | NTL Biotech | 14.3% |
| 7 | PerkinElmer Inc. | 14.3% |
Derivation Method
The ranking is calculated based on the click share within the nucleic acid extraction system page as of March 2023. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- PerkinElmer Inc.: 14,000
Newly Established Company
- GeneReach Biotechnology Corp.: 2004 (19 years ago)
- Geneaid Biotech Ltd.: 2002 (21 years ago)
- Advanced Biological Laboratories (ABL), S.A.: 2000 (23 years ago)
Company with a History
- Esco Micro Pte. Ltd.: 1978 (45 years ago)
- Daan Gene Co., Ltd.: 1993 (30 years ago)
- ACON Laboratories, Inc.: 1996 (27 years ago)
Lists of Nucleic Acid Extraction System Products
3 products are listed.
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