All Categories
History
This section provides an overview for lipid nanoparticles as well as their applications and principles. Also, please take a look at the list of 8 lipid nanoparticle manufacturers and their company rankings. Here are the top-ranked lipid nanoparticle companies as of December, 2024: 1.ABP Biosciences, LLC, 2.Creative BioStructure, 3.BOC Sciences.
Table of Contents
Lipid nanoparticles (LNP) are nanoscale particles made of lipids that are widely used in the pharmaceutical industry. Their structure allows for the encapsulation of various types of drugs: water-soluble drugs in their aqueous core, and lipophobic drugs in the hydrophobic parts. This versatility makes them ideal for drug delivery systems (DDS), where they can transport medications directly to targeted tissues.
Modifications to the size of lipid nanoparticles or the addition of surface antibodies enable precise drug delivery. LNPs are also being utilized to create nano-gas bubbles for medical purposes, encapsulating medical gases within the particles.
Lipid nanoparticles have been instrumental in developing treatments for various medical conditions, including cancer. One of the most notable recent applications is in COVID-19 vaccines, where LNPs encapsulate mRNA, the genetic blueprint for the virus's protein, facilitating effective immune response stimulation.
The manufacturing of lipid nanoparticles requires precision to ensure a consistent and effective particle size distribution, which is crucial for drug delivery and controlled release. In pharmaceuticals, particle size significantly impacts the rate of drug absorption and release.
Traditional batch processing methods often struggle with maintaining consistent control over the synthesis process, which can result in particle agglomeration and a broad size distribution. However, microfluidic technology offers a more refined approach. Due to its low Reynolds number and diffusion-dominated characteristics, microfluidics is increasingly preferred for LNP production.
In this process, a water-soluble fluid is combined with a lipid-soluble fluid within a microfluidic channel. The interaction between these two fluids leads to the self-assembly of lipid particles. By adjusting the mixing ratio and flow velocity of the two fluids, precise control over particle size can be achieved, ensuring uniformity and effectiveness in drug delivery.
*Including some distributors, etc.
Sort by Features
Sort by Area
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Creative BioStructure, established in 2005 and based in Shirley, New York, USA, is a manufacturer and supplier of structural biology and membrane protein technologies products. The company's product range includes UniCrys Crystallization Products, MagHelix Electron Microscopy Products, Virus-like Particle Products, Liposome Products, and Exosome Products. These products support detailed studies in structural biology. These products serve industries such as academia, biotech, pharmaceutical, and research sectors. The company offers services like Structural Biology Services, Custom Protein Production, Protein Engineering and Analysis, and Virus-like Particle (VLP) Services.
CD Bioparticles, founded in Shirley, New York, is a manufacturer of biocompatible drug delivery systems. The company's product portfolio includes Liposomes, PEGylated liposomes, Polymer microspheres, Nanoparticles and Functional Biomedical Coatings. Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and healthcare. They also provide Contract services of drug delivery formulation developments, Product Selection Guidance, customer support, custom research projects and customized services.
BOC Sciences is headquartered in Shirley, New York as a brand of BOCSCI Inc. The company is a developer, manufacturer, marketer, and distributor of premium chemicals, emphasizing small molecule synthesis, biosynthesis, purification, and characterization used in academia, pharmaceuticals, biotech, CDMO, material sciences, and agriculture industries, supporting research and production. The company’s products include thousands of inhibitors, nucleotides, metabolites, and isotope-labeled products. The company offers custom synthesis and manufacturing, analytical services, antibody-drug conjugate development, and strain engineering and fermentation services.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | ABP Biosciences, LLC |
22.9%
|
| 2 | Creative BioStructure |
14.6%
|
| 3 | BOC Sciences |
13.2%
|
| 4 | CD Bioparticles |
12.5%
|
| 5 | Lonza |
11.1%
|
| 6 | Acuitas Therapeutics |
10.4%
|
| 7 | CordenPharma International |
7.6%
|
| 8 | MilliporeSigma |
7.6%
|
Derivation Method
The ranking is calculated based on the click share within the lipid nanoparticle page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
1 | 33.3% |
Germany
|
1 | 33.3% |
Canada
|
1 | 33.3% |
16 products found
16 products
Nippon Talc Co., Ltd.
70+ people viewing
Last viewed: 1 day ago
Very Fast Response
■Product overview When talc is made into fine particles using conventional technology, the plate-like particle shape is lost, making it impossible ...
Nippon Talc Co., Ltd.
70+ people viewing
Last viewed: 3 hours ago
Very Fast Response
■Product overview This is an ultrafine talc powder developed by our company ahead of Nano Ace. It is used not only in existing talc applications, b...
Nippon Talc Co., Ltd.
60+ people viewing
Last viewed: 4 hours ago
Very Fast Response
■Product overview Talc is compressed to increase its apparent density and improve its kneading ability with resin. There is less dust when charging...
Nippon Talc Co., Ltd.
60+ people viewing
Last viewed: 1 day ago
Very Fast Response
By taking advantage of talc's inherent characteristics such as high whiteness, plate-like crystals, and chemical resistance, Micro Ace® can be used...
Nippon Talc Co., Ltd.
50+ people viewing
Last viewed: 1 day ago
Very Fast Response
General-purpose talc is used as a compound filler in a wide range of fields including plastics, paper, rubber, paints, and ceramics.
Nippon Talc Co., Ltd.
20+ people viewing
Last viewed: 1 day ago
Very Fast Response
Nippon Talc Co., Ltd.
70+ people viewing
Last viewed: 1 day ago
Very Fast Response
A new grade with revolutionary luster
Nippon Talc Co., Ltd.
40+ people viewing
Last viewed: 1 day ago
Very Fast Response
■Product overview This talc meets the standards based on the Food Additives Official Standards and has obtained Halal certification. It also compli...
Nippon Talc Co., Ltd.
40+ people viewing
Last viewed: 28 minutes ago
Very Fast Response
This talc meets standards based on quasi-drug raw material standards and has acquired Halal certification.
Nippon Talc Co., Ltd.
70+ people viewing
Last viewed: 1 day ago
Very Fast Response
■Product overview This talc complies with the Japanese Pharmacopoeia and is Halal certified. Compatible with USP and EP.
Nippon Talc Co., Ltd.
30+ people viewing
Last viewed: 1 day ago
Very Fast Response
■Product overview High whiteness powder made by crushing and firing a special raw stone. Processed under strict quality control to improve electric...
Nippon Talc Co., Ltd.
40+ people viewing
Last viewed: 21 hours ago
Very Fast Response
■Product overview By chemically and physically bonding a treatment agent such as a silane coupling agent to the talc surface, it is possible to imp...
Nippon Talc Co., Ltd.
50+ people viewing
Last viewed: 1 day ago
Very Fast Response
Manufactured under strict quality control based on the laws and regulations of the Ministry of Health, Labor and Welfare, it meets the standards ba...
Nippon Talc Co., Ltd.
50+ people viewing
Last viewed: 1 day ago
Very Fast Response
Talc is purified from carefully selected raw materials based on Japanese Pharmacopoeia standards. Used as an excipient and lubricant for tablets.
Nippon Talc Co., Ltd.
50+ people viewing
Last viewed: 1 day ago
Very Fast Response
It has a high apparent density and low oil absorption, so it is used in cosmetics and paints.
Nippon Talc Co., Ltd.
50+ people viewing
Last viewed: 6 hours ago
Very Fast Response
Talc for papermaking is classified into internal filling and pitch control, and uses carefully selected raw materials that are less abrasive to pap...
