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This section provides an overview for microfluidics as well as their applications and principles. Also, please take a look at the list of 26 microfluidics manufacturers and their company rankings. Here are the top-ranked microfluidics companies as of December, 2024: 1.PerkinElmer Inc., 2.CPS Fluidics, 3.LabSmith.
Table of Contents
Microfluidics involves manipulating fluid flow within channels that typically range from 1 micrometer to 1 millimeter in width. In these microscale environments, surface tension and viscosity play more significant roles than gravity and inertial forces, which are predominant in larger-scale fluid mechanics.
Microfluidic channels are created using semiconductor microfabrication technology. This miniaturization allows for reduced reagent usage and improved reaction efficiency by leveraging the unique properties of micro-spaces.
Microfluidic devices find applications in various fields, combining engineering technologies like miniaturization, reduced reaction temperature energy, electrochemistry in micro-spaces, sensor integration, and automation. These devices facilitate faster and more efficient chemical reactions due to the significant effect of molecular diffusion in a large specific surface area, especially when two fluids are mixed.
Microfluidics is crucial in producing monodisperse droplets for pharmaceutical and cosmetic applications, encapsulating cells in droplets for culture in tiny test tubes or petri dishes, and performing high-throughput analysis. This analysis is often enhanced by integrating cell-encapsulated droplets with Fluorescence-Activated Cell Sorting (FACS) and sequencers.
Diverse microfluidic channel designs have been developed for specific applications, using materials like PDMS, glass, and plastic. Droplet formation typically occurs in cross-shaped microfluidic channels. Here, two immiscible fluids – the dispersed and continuous phases – are pumped into the channels.
At the junction, the continuous phase flows through the upper and lower channels, while the droplet-forming solution is introduced from the side. Micro-droplets are created by the shear force at the junction, effectively pinching and cutting the solution in the droplet phase.
The size of these droplets can be controlled by the flow rate ratio of the two fluids. While increasing the flow rates can boost droplet production, excessively high velocities may prevent proper droplet formation and result in jet flow instead.
*Including some distributors, etc.
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ALine Provides Microfluidic Solutions for the Pharmaceutical, Biotech, IVD, Diagnostic and Point of care markets. We engineer single use consumables that integrate sample prep and detection using biosensors, optical or electroactive sensors. We are experts at the integration of membranes, microfluidic valves, microfluidic pumps and microfluidic mixers located in 13,000 sq.ft., we do rapid prototyping, engineering and manufacture all under one roof. our expert support has lead to over $3.1 billion in follow on funding.
PerkinElmer Inc., founded in 1937, is an American manufacturer headquartered in Waltham, Massachusetts, specializing in laboratory technology and management. The company's product offerings include analysis and characterization instruments, software, and consumables. Such offerings cover chromatography, mass spectrometry, molecular and atomic spectroscopy. They also provide immunoassay and food quality analyzers, as well as the simultaneous thermal analyzer (STA). These products find applications in various industries, such as biopharmaceuticals, food safety, lithium battery, and water resource management. PerkinElmer also offers OneSource Laboratory Services, providing knowledge, application, and service solutions for scientific laboratories. Additionally, their LABStartUp program supports new laboratories with instrumentation, consumables, and funding.
CPS Fluidics., founded in Connecticut, United States in 2021, is a manufacturer of a range of custom fluidic products from large scale flow cells to microfluidic devices. The company's product portfolio includes flow cells that enable selective detection and measurement of a wide range of physical, chemical, or biological properties, microfluidics miniaturized assay workflow to decrease assay volumes, and process solutions to support the science behind the flow cells and microfluidic systems, including interfaces/connections, machining hard materials, and diverse combinations of materials and bonding techniques.
Hudson Medical Innovations, based in Hudson, Wisconsin, U.S.A., is a manufacturer of healthcare devices for various applications in the medical industry. The company provides microfluidics, advanced wound care devices, and wearable biosensors as well as offers COVID test, high-density micro-perforating laser cutting & ablation, rotary & flatbed die cutting, automated robotic multi-layer lamination, and, packaging & turnkey assembly services for the medical sector. The company has ISO 9001:2015, ISO 13485:2016, and, ISO 14644 certifications, and the products are made of silicone & acrylic pressure-sensitive adhesives, polyester films, and, cyclic olefin copolymer.
Unchained Labs Inc., founded in 2015, is a life science tool manufacturer headquartered in Pleasanton, California, United States. The company develops various products for the biology field, such as systems for nucleic acid and protein quantification, as well as tools for lentivirus and exosome characterization. It also provides solutions for cell and gene therapy, genomics quantification and quality control, and lipid nanoparticle (LNP) formulation screening. These products are utilized in the academic, biotechnology, and pharmaceutical sectors.
LabSmith, Inc., established in 1995 and based in Livermore, California, is a manufacturer of laboratory equipment for research and product development. Its product range includes microfluidics for fluid flow control, microfluidic chipShop chips, programmable high-voltage sequencers, research-grade microscopes, and precision timing and synchronization products. Its video microscopes capture elusive events in microfluidic or microbiology experiments, with triggering and timing based on real-world feedback. Its products are used around the world, from university teaching labs to global biotechnology companies.
Suzhou Wenhao Microfluidic Technology Co., Ltd , established in 2012 in Suzhou, Jiangsu, China, is a manufacturer of microfluidic technology products and devices. The company manufactures a diverse range of products, including microfluidic chips, microfluidic devices, and lab-on-a-chip systems for precise sample manipulation, optimal-throughput analysis, and reduced reagent consumption, supporting efficient and accurate lab processes. Industries spanning from life sciences and biotechnology to pharmaceuticals and diagnostics use the products for advanced microfluidic applications. Its specialization in microfluidics offers advantages in miniaturization, automation, and genuine-throughput analysis, making advanced lab processes and scientific discoveries possible.
ALPS ALPINE CO., established in 1948, is a manufacturer and supplier of sensors＆communication, modules＆systems, and components based in Tokyo, Japan. The company serves the energy, healthcare, automotive, mobile, and consumer electronics domains, where they combine and build on core device technology, including human-machine interfaces, SENSORING™, and connectivity. For example, in the healthcare industry, they supply components for medical equipment, including control switches, sensors, lenses, and joysticks, and the Senclear™ Microfluidic Devices for drug discovery and development. Their power conversion modules, current sensors inverters, and converters are used in the energy industry in storage batteries, solar power systems, and electric vehicle charging systems.
Fluigent, founded in 2005 and located in Le Kremlin-Bicêtre, France, is a developer and manufacturer of fluid control systems. The company offers a broad range of products that include microfluidic devices, modular OEM microfluidic flow controllers, microfluidic OEM pressure controllers, and OEM microfluidic pressure sources. These products find general use in the field of microfluidics, allowing for the precise manipulation and control of small fluid volumes. The company’s products cater to industries, including life sciences for genomics and cell analysis, drug discovery, biotechnology, chemical analysis, and diagnostics.
Alfa Chemistry, founded in the year 2015 is based in New York, USA as a biotechnology company and manufacturer of graphene materials. Their product portfolio includes graphene oxide, CVD graphene film, graphene modification services, graphene series, graphene-like material, carbon nanomaterials, quantum dots, upcoming nanoparticles, and graphene transfer services. The company also provides services in custom manufacturing, and graphene analysis with quality assurance. The products are used in various industries which include energy, digital electronics, environment, textile, coating, and biomedical science.
AGC Inc., founded in Amagasaki, Japan, in 1907 is a supplier of flat, automotive, display glass, chemicals, ceramics and other high-tech materials and components. The company's product portfolio includes Architectural glasses, Automotive glasses, Architectural Materials, performance chemicals and Biopharmaceuticals. Their products are used in markets such as Automotive and Transportation, Telecommunications, Industrial Automation, Healthcare and Medical Devices and Aerospace and Defense. They also offer custom packaging, warehousing, customer service and distribution services.
Enplas Corporation, established in 1962 and headquartered in Tokyo, Japan, is a manufacturer of Plastic Processing, Optical and Electronic, and Life Science. The company offers a wide range of products, including custom injection molded plastic, in-vitro diagnostics, thermoplastic elastomer fluid seals, bioprocessing, and PCR. It also offers microfluidic chips and flowcells, cleanroom consumables, and NGS. Its product offers complex channels with dense nanowell structures, high aspect ratios, and more. The company is ISO 14001 and IATF 16949:2016 certified. It serves various industries such as manufacturing, medical and life sciences, automotive, communication, and more.
Philips Engineering Solutions, established in 2011 and headquartered in Eindhoven, Netherlands, is a manufacturer of custom systems and devices, including microelectromechanical systems (MEMS), assembled microdevices, connectivity solutions, and more. The company's key areas of expertise revolve around medical device design & engineering, high-precision engineering, electronic systems & IoT, Philips MEMS & microdevices, manufacturing systems & Industry 4.0, and more. The company serves diverse industries, including healthcare, high-tech, and semiconductors. It has established partnerships with organizations such as Signify, Gilbert Technologies, Thales, ASML, ABIOMED, and numerous others.
Kyodo International, Inc. established in 1970 and based in Kawasaki-shi, Japan, is a manufacturer and distributor of microfabrication tools and equipment. The company's product range includes deposition tools, photolithography equipment, etching machines, CMP processing units, and nanoimprinting tools. These products are used for the development and manufacturing of electronic components and systems. The company serves industries such as electronics manufacturing, microelectromechanical systems (MEMS) production, and life sciences, it ensures the delivery of high-precision tools for intricate manufacturing processes. Its services span the sale, repair, and overhaul of consumable parts.
IDEX Health & Science, established in 1971 and headquartered in Rohnert Park, California, USA, is a manufacturer and supplier of fluidics and optics products and solutions. The company’s fluidics product range includes valves, connectors, filters, and other components vital for precise fluid control. In optics, they offer microscopes, imaging systems, and optical instruments. These products find applications in various fields, including medical diagnostics, pharmaceutical research, industrial manufacturing, environmental monitoring, and food/beverage testing. Devoted to quality and sustainability, the company serves its global customers with over 7,000 employees under the umbrella of IDEX Corporation.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | PerkinElmer Inc. |
10.9%
|
| 2 | CPS Fluidics |
9.5%
|
| 3 | LabSmith |
7.7%
|
| 4 | Hudson Medical Innovations |
7.6%
|
| 5 | Alfa Chemistry |
5.1%
|
| 6 | Philips Engineering Solutions |
4.7%
|
| 7 | Unchained Labs |
4.6%
|
| 8 | ALine, Inc. |
4.1%
|
| 9 | Plastic Design Company |
4.1%
|
| 10 | Fivephoton Biochemicals |
3.8%
|
Derivation Method
The ranking is calculated based on the click share within the microfluidics page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
10 | 47.6% |
|
Japan
|
3 | 14.3% |
|
China
|
2 | 9.5% |
United Kingdom
|
2 | 9.5% |
|
France
|
1 | 4.8% |
| United States | 1 | 4.8% |
Netherlands
|
1 | 4.8% |
Singapore
|
1 | 4.8% |
