All Categories
History
This section provides an overview for xanthine as well as their applications and principles. Also, please take a look at the list of 7 xanthine manufacturers and their company rankings. Here are the top-ranked xanthine companies as of December, 2024: 1.SRL, 2.Alpha Chemika, 3.SUVCHEM.
Table of Contents
Xanthine, an organic compound with the chemical formula C5H4N4O2, is a colorless or white solid found in body fluids, tissues, urine, blood, coffee beans, and tea. It is produced in the body from a purine base and metabolized to urea by xanthine oxidase.
Xanthine is explored as a marker of tissue hypoxia. It increases in concentration due to ischemic injury, indicating potential oxygen deprivation in tissues. Derivatives like theobromine and caffeine are used in pharmaceuticals for their stimulant properties.
Xanthine sublimates partially when heated, decomposes above 300°C, and is insoluble in water and ethanol. It dissolves in mineral acids, aqueous ammonia, and aqueous sodium hydroxide, and is converted to uric acid by oxidase. It exists in multiple tautomeric forms.
Xanthine is synthesized chemically from guanine with sulfuric acid and sodium nitrite and naturally produced in vivo from adenine and hypoxanthine.
Xanthine derivatives, or xanthines, include caffeine, theobromine, theophylline, and paraxanthine. Caffeine, for instance, is 1,3,7-trimethylxanthine, known for its psychostimulant effect.
Xanthine alkaloids are used as mild stimulants and bronchodilators. However, due to their narrow therapeutic range, they are often not the first choice for long-term asthma control. Toxicity symptoms include tremors, irritability, nausea, tachycardia, and arrhythmia.
*Including some distributors, etc.
Sort by Features
Sort by Area
Alpha Chemika, founded in 1989 and based in Mumbai, India, is a manufacturer, supplier of laboratory reagents and fine chemicals. Their products are used in multiple industries, including pharmaceutical, chemical, biotechnology, and environmental. Their product portfolio ranges from chemicals such as Silver Nitrate, Perchloric Acid, and Lanthanum Acetate to laboratory tools and equipment such as Air Inlet Tubes, Air Inlet Tubes, and Optical Components. Alpha Chemika has been able to obtain ISO 9001:2000 certification.
Hefei TNJ Chemical Industry Co., Ltd, established in 2001, is headquartered in China. The company is a chemical manufacturer and supplier of chemicals to domestic Chinese and global consumers in four primary markets: chemicals, food, pharmaceuticals, and personal care. Chemicals include fine chemicals, agrochemicals, and other chemicals. Food includes agrochemicals, vitamins, amino acids, and food ingredients. Pharmaceuticals include specific chemicals such as Povidone iodine, Clotrimazole crystalline, and Lincomycin. The company also features a CAS databank for CAS-registered chemical compounds.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
SUVCHEM, established in 2004 and headquartered in Mumbai, India, is a manufacturer and exporter of laboratory chemicals and reagents. Their diverse product range includes organic and inorganic chemicals utilized in pharmaceuticals, plastics, water treatment, and more. They also offer biological stains and indicators for laboratory applications like cell culture and DNA analysis, along with culture media ingredients for growing microorganisms. SUVCHEM's products cater to schools, colleges, research laboratories, pharmaceutical and chemical companies, and other industries, supporting teaching, research, product development, and manufacturing processes across various sectors.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | SRL |
52.4%
|
| 2 | Alpha Chemika |
19.0%
|
| 3 | SUVCHEM |
14.3%
|
| 4 | Hefei TNJ Chemical Industry Co.,Ltd. |
4.8%
|
| 5 | MilliporeSigma |
4.8%
|
| 6 | nacalai |
4.8%
|
Derivation Method
The ranking is calculated based on the click share within the xanthine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
3 | 60.0% |
|
China
|
1 | 20.0% |
|
Japan
|
1 | 20.0% |
