This section provides an overview for adenine as well as their applications and principles. Also, please take a look at the list of 10 adenine manufacturers and their company rankings. Here are the top-ranked adenine companies as of November, 2024: 1.Hangzhou Jeci Biochem Technology Co., Ltd., 2.Manus Aktteva Biopharma LLP, 3.Hangzhou Longshine Bio-Tech Co.,LTD.
Table of Contents
Adenine is an organic compound with a purine skeleton, also known as 6-aminopurine and 9H-Purin-6-amine in IUPAC nomenclature. It is one of the five nucleobases in nucleic acids, widely present in living organisms. Adenine is a colorless or pale yellow solid at room temperature with a molecular formula of C5H5N5, a molecular weight of 135.13, and decomposes at a melting point of 680°F. It is insoluble in water, ethanol, and acetone, but soluble in dilute hydrochloric acid, sodium hydroxide, and ammonia.
Adenine is a component of nucleic acids like DNA and RNA. It is used to treat leukopenia caused by radiation exposure or drugs, in semiconductor corrosion prevention, and sex identification of fish.
Adenine acts as a base with pKa values of 4.15 and 9.08, being part of DNA and RNA. Its corresponding nucleosides are adenosine (A) and deoxyadenosine (dA), forming hydrogen bonds with thymine in DNA and uracil in RNA. It is also a component of coenzymes A, FAD, NAD, and the energy substance ATP.
In vivo, adenine is biosynthesized by purine metabolism, converting ribose-5-phosphate to inosinic acid (IMP), then to adenylic acid (AMP) and guanosine monophosphate (GMP). Industrially, it is synthesized by heating formamide, with increased yields using phosphoryl chloride (POCl3) or phosphorus pentachloride (PcL5) as acid catalysts.
As a drug, adenine is available in 10 mg tablets for treating radiation exposure and drug-induced leukopenia. It is also sold as a research reagent, available in various purities, and packaged in quantities like 1g, 25g, 100g, and 250g. It should be stored at room temperature, away from light, and mindful of hazardous decomposition products like CO, CO2, and NOx.
*Including some distributors, etc.
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Avanschem, established in 2012, a manufacturer of a wide range of products such as cyanuric acid, pegelatinized sarch, welan gum, and more, operating from a prime location of Gurgaon, Haryana, India. The company provides products developed from of top-notch ingredients and industrial chemicals, for lab and Industrial use. These products formulated using chemical compounds under controlled temperature and pressure conditions at their sophisticated laboratory. They specialize in formulations & contract manufacturing, dossiers services, sourcing services and others, with a worldwide distribution network.
Manus Aktteva Biopharma LLP, established in 2010 and headquartered in Ahmedabad, India, is a manufacturer, supplier, and exporter of pharmaceutical APIs, intermediates, and specialty chemicals. Their wide-ranging products cater to industries such as pharmaceutical, nutraceutical, and biotechnology. They offer Active Pharmaceutical Ingredients (APIs), the fundamental components used in various drug formulations, such as antibiotics, cardiovascular drugs, and anti-inflammatory drugs. The company also supplies specialty chemicals with unique properties applicable to diverse industries, from plastics to cosmetics manufacturing. Furthermore, the company offers custom synthesis services to meet the specific needs of their customers.
Hangzhou Jeci Biochem Technology Co., Ltd., was established in 2002 and headquartered in Hangzhou, Zhejiang province, is a manufacturer of active pharmaceutical ingredients and intermediates. The company provides an extensive and diverse product portfolio, including anti-inflammatory drugs, Nirmatrelvir intermediates, anti-hyperlipidemia drugs, anti-tumor drugs, and anti-virus drugs. These active pharmaceutical ingredients and intermediates are integral in various applications, serving as pharmaceutical intermediates, industrial raw materials, chemical components, and essential substances for advanced intermediate production.
Alpha Chemika, founded in 1989 and based in Mumbai, India, is a manufacturer, supplier of laboratory reagents and fine chemicals. Their products are used in multiple industries, including pharmaceutical, chemical, biotechnology, and environmental. Their product portfolio ranges from chemicals such as Silver Nitrate, Perchloric Acid, and Lanthanum Acetate to laboratory tools and equipment such as Air Inlet Tubes, Air Inlet Tubes, and Optical Components. Alpha Chemika has been able to obtain ISO 9001:2000 certification.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
SUVCHEM, established in 2004 and headquartered in Mumbai, India, is a manufacturer and exporter of laboratory chemicals and reagents. Their diverse product range includes organic and inorganic chemicals utilized in pharmaceuticals, plastics, water treatment, and more. They also offer biological stains and indicators for laboratory applications like cell culture and DNA analysis, along with culture media ingredients for growing microorganisms. SUVCHEM's products cater to schools, colleges, research laboratories, pharmaceutical and chemical companies, and other industries, supporting teaching, research, product development, and manufacturing processes across various sectors.
Hangzhou Longshine Bio-Tech Co., Ltd., established in 2011 and headquartered in Hangzhou, Zhejiang, China, is a manufacturer and supplier of pharmaceutical and chemical goods. The company offers a wide range of products, including API and intermediates, conjugated estrogens, beta-alanine, adrenaline tartrate, and 5-bromopyridine-2-carbaldehyde. These chemical products serve various purposes, such as being potent orally active estrogen receptor antagonists with anticancer properties, regulating animal physiology, diagnosing animal diseases, and providing treatments for conditions like erectile dysfunction.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Glentham Life Sciences is based in Corsham, United Kingdom. Glentham Life Sciences is a leading supplier of fine chemicals, raw materials, reagents, and life science products. Glenthem also offers a number of services including custom packaging, call-off orders, and safety documentation. Glentham’s product offerings include chemicals such as amino acids, antibiotics, APIs, biochemicals, buffers, carbohydrates, chitin, chitosan, detergents, dyes, stains, enzymes, inorganic, peptide reagents, phytochemical, raw materials, solvents, steroids, and vitamins among others.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Hangzhou Jeci Biochem Technology Co., Ltd. |
25.0%
|
2 | Manus Aktteva Biopharma LLP |
25.0%
|
3 | Hangzhou Longshine Bio-Tech Co.,LTD |
12.5%
|
4 | Xi an Sost Biotech CO,. Ltd. |
12.5%
|
5 | SUVCHEM |
12.5%
|
6 | Central Drug House |
12.5%
|
Derivation Method
The ranking is calculated based on the click share within the adenine page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
India | 4 | 50.0% |
China | 3 | 37.5% |
United Kingdom | 1 | 12.5% |