13 Formamide Manufacturers in 2024
This section provides an overview for formamide as well as their applications and principles. Also, please take a look at the list of 13 formamide manufacturers and their company rankings. Here are the top-ranked formamide companies as of November, 2024: 1.Alfa Aesar, Thermo Fisher Scientific., 2.Santa Cruz Biotechnology, Inc., 3.Junsei Chemical Co.,Ltd..
Table of Contents
What Is Formamide?
Formamide is an amide derived from formic acid with the chemical formula HCONH2. It is also known as methanamide and carbamaldehyde.
The 50% lethal dose (LD50) of formamide is a few grams per kilogram, indicating low acute toxicity and low mutagenicity.
Uses of Formamide
Formamide is used as an anti-freezing agent, and in cryopreservation of biological samples, such as mouse sperm. It acts as a "vitrification compound" that solidifies and supercools the object.
Additionally, formamide is utilized in the industrial production of hydrogen cyanide (HCN), a highly toxic substance used as an insecticide and rat poison.
Formamide is also employed in RNA stabilization in gel electrophoresis, stabilization of denatured DNA strands in capillary electrophoresis, synthesis of vitamins, production of sulfa drugs, and as a paper and fiber softener.
Properties of Formamide
Formamide is a colorless liquid with an ammoniacal odor. It has a melting point of 2-3 °C and a boiling point of 210 °C. It is miscible with alcohol and ether but insoluble in benzene and chloroform.
As a solvent, formamide can mix with water in any proportion and dissolve ionic compounds insoluble in water, including alkali metal salts of acetic acid and chlorides of lead, copper, and iron, as well as polymer compounds like glucose, casein, starch, and tannin.
Structure of Formamide
Formamide, with the differential formula HCONH2, is an amide of formic acid. It has a molecular weight of 45.04 g/mol and a density of 1.133 g/cm3.
Formamide is hypothesized as an alternative solvent to water in biochemistry due to its ability to sustain life and its production through the hydrolysis of hydrogen cyanide. Its large dipole moment gives it solvation properties similar to water.
Other Information on Formamide
1. Synthesis of Formamide
Formamide can be synthesized industrially by treating formic acid with ammonia to produce ammonium formate, which is then dehydrated. It can also be produced by aminolysis of methyl or ethyl formate with ammonia, or by carbonylation of ammonia.
Another method involves ammonolysis of methyl formate produced from carbon monoxide and methanol.
2. Reaction of Formamide
At 180 °C, formamide decomposes into carbon monoxide and ammonia. In the presence of a solid acid catalyst, it decomposes into hydrogen cyanide and water.
When heated under ultraviolet light, formamide can convert to trace amounts of guanine.
List of 13 Formamide Manufacturers
*Including some distributors, etc.
Sort by Features
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- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Japan
- United Kingdom
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Promega Corporation
Formamide, Molecular Grade
Manufacturer Overview
Promega Corporation, founded in 1978 and headquartered in Madison, Wisconsin, operates as a manufacturer of enzymes and products catering to biotechnology and molecular biology. Its extensive product range covers genomics, protein analysis, cellular analysis, drug discovery, and genetic identity products, which are utilized in various fields of scientific research. Additionally, the company offers custom solutions, including a wide range of capabilities in manufacturing, technology development, assay automation, and inventory management. The company has obtained certification to international standards for quality management systems in 1998.
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Santa Cruz Biotechnology, Inc.
Formamide
Company Overview
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
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Thermo Fisher Scientific Inc.
Formamide
Company Overview
Thermo Fisher Scientific Inc., founded in 1956 and headquartered in Waltham, Massachusetts, is a manufacturer and supplier of life science solutions, analytical instruments, specialty diagnostics, laboratory products, and biopharma services. Through its brand names, including Invitrogen, Fisher Scientific, Patheon, Applied Biosystems, and Gibco, among others, the company provides a wide range of products, which include chromatography systems, thermal cyclers, automated cell counters, fermenters, and DNA polymerases. The company’s annual revenue is over 40 billion USD, and it serves several fields, including customers working in clinical diagnostic labs, research institutions, hospitals, government agencies, and pharmaceutical/biotech companies.
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Amerigo Scientific.
Formamide
Distributor Overview
Amerigo Scientific., founded in New York, US, is a distributor of Automated Nucleic Acid Extraction Systems, biomedical and chemical products. The company's product portfolio includes 3D Bioprinters, Biomaterials & Bioinks, Cells, Cell Media & reagents, Lab Equipment and Electrophoresis Systems. Their products are used in industries such as Food and Beverage , Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and healthcare. The company also provides services including national distribution, product selection, customized services, technical support and customer service.
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KANTO CHEMICAL CO.,INC.
Formamide
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Junsei Chemical Co.,Ltd.
Formamide
Manufacturer Overview
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
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Kishida Chemical Co.,Ltd.
Formamide
Manufacturer Overview
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
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FUJIFILM Wako Pure Chemical Corporation
Formamide
Manufacturer Overview
FujiFilm Wako Pure Chemical Corporation, founded in 1922 and headquartered in Osaka, Japan, is a manufacturer of laboratory chemicals, specialty chemicals, and clinical diagnostic reagents. The company has three business domains, namely laboratory chemicals, specialty chemicals, and clinical diagnostic reagents, and some of its products include biochemistry reagents, blood transfusion test drugs, battery materials, polymer-related materials, and general reagents. The products are useful in various fields, including electronic, cosmetic, polymeric, pharmaceutical, and medical care. It acquired Sibayagi Co. Ltd. in 2015 and provides custom manufacturing to meet customer requirements.
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Merck
Formamide
Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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Honeywell
Formamide
Manufacturer Overview
Honeywell, founded in 1906, in Wabash, Indiana is manufacturer of automotive parts, building technologies, and performance and safety materials for aerospace, The company's product portfolio includes electronic guidance systems, cockpit instrumentation, lighting, automotive parts, and primary propulsion and secondary power turbine engines. The company serves industries such as Oil and Gas, Aerospace and Defense, Automotive and Transportation, Construction, and Power Generation. Their headquartere is located in Carolina and they have global sales offices and distributions channels.
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MilliporeSigma
Formamide
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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nacalai
Formamide
Company Overview
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
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Alfa Aesar, Thermo Fisher Scientific.
Formamide
Company Overview
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
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Formamide Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Alfa Aesar, Thermo Fisher Scientific. |
33.3%
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| 2 | Santa Cruz Biotechnology, Inc. |
22.2%
|
| 3 | MilliporeSigma |
22.2%
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| 4 | Junsei Chemical Co.,Ltd. |
11.1%
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| 5 | Thermo Fisher Scientific Inc. |
11.1%
|
Derivation Method
The ranking is calculated based on the click share within the formamide page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
- Kishida Chemical Co.,Ltd.: 283
- Junsei Chemical Co.,Ltd.: 171
Newly Established Company
- Junsei Chemical Co.,Ltd.: 1948 (76 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- nacalai: 1934 (90 years ago)
Company with a History
- FUJIFILM Wako Pure Chemical Corporation: 1922 (102 years ago)
- nacalai: 1934 (90 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
Formamide Manufacturers in United States
*Including some distributors, etc.
- Promega Corporation
- Santa Cruz Biotechnology, Inc.
- Thermo Fisher Scientific Inc.
- Amerigo Scientific.
Global Distribution of Formamide Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
Japan
|
5 | 50.0% |
United States of America
|
4 | 40.0% |
United Kingdom
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1 | 10.0% |
