This section provides an overview for ethyl formate as well as their applications and principles. Also, please take a look at the list of 10 ethyl formate manufacturers and their company rankings. Here are the top-ranked ethyl formate companies as of November, 2024: 1.CAMEO Chemicals, 2.Junsei Chemical Co.,Ltd., 3.ChemUniverse, Inc..
Table of Contents
Ethyl Formate is an organic compound classified as a carbonate ester.
As a natural product, it is found in fruits such as pineapple and raspberries, cabbage, vinegar, butter, and brandy, and has a sweet fruity odor.
Its chemical formula is C3H6O2 and it is a colorless liquid with a molecular weight of 74.08. Its boiling point is 54.3℃ and its flash point is -20℃. When mixed with air, ethyl formate produces explosive gases. It is synthesized by reacting ethanol and carbon monoxide in the presence of a strong base.
Ethyl Formate is used in a variety of applications, including as a flavoring agent in fruit flavors such as pineapple and in Western liquors such as whiskey, rum, and brandy. When sniffed in high concentrations, pure ethyl formate alone smells like a glue or nail polish remover.
At lower concentrations, however, the smell changes to the sweet smell characteristic of fresh fruit when first cut. It is common for the same ingredient to give a different aroma impression at higher and lower concentrations.
As a special example, it is said that ethyl formate adheres to spacesuits during spacecraft extra-vehicular activities. This is in trace amounts that has little to do with its use or manufacture on Earth, and may come from the formation of organic matter in space or from the combustion of spacecraft fuel. This rare phenomenon has led to the development of perfumes that reproduce the scent of space containing ethyl formate, as well as products themed around space activities.
There are also examples of its use as a non-electrolyte solvent in rechargeable batteries. When ethyl formate is used as a non-electrolyte solvent mixed with a compound that simultaneously has acrylic groups, the increase in battery thickness can be greatly reduced when stored at high temperatures. Even when mixed with other electrolyte additives, it has been confirmed that no offsetting or reduction in its effect occurs.
Ethyl formate, along with methyl formate, has been attracting attention as an electrolyte solvent for new high-performance rechargeable batteries.
Ethyl Formate is slightly soluble in water. The ester bond is polarized and has a carboxyl group like water molecules. Therefore, it is slightly soluble in water due to the formation of hydrogen bonds with water molecules. Containing ethyl groups that are compatible with oil, it is extremely soluble in ethanol and acetone.
In general, the boiling point of a substance increases with its molecular weight. This is because the larger the molecular weight, the greater the intermolecular forces acting between molecules. In order to shake off the large intermolecular forces and vaporize the substance, it is necessary to give it a large amount of energy.
However, when formic acid forms an ester with methanol or ethanol, the boiling point of the ester is higher than that of formic acid, even though the molecular weight has increased. This is because formic acid and ethyl formate do not form hydrogen bonds with each other, whereas formic acid and ethyl formate form hydrogen bonds with each other.
Ethyl Formate has a distinctive aroma, with a sweet smell characteristic of fresh fruit. This is because ethyl formate is naturally occurring in fruits, such as raspberries and pineapples.
Formic acid and ethanol are mixed, and when a catalyst is added, ethyl formate is formed by esterification. A strong acid such as concentrated sulfuric acid is used as a catalyst. In this reaction, H+ from sulfuric acid acts as a catalyst, and at the same time, the water produced is hydrated with concentrated sulfuric acid and eliminated from the reaction system, so the equilibrium in the figure below shifts to the right.
Ethyl formate liquid and vapor are flammable. It may also be irritating to the eyes and respiratory tract. It must be handled with care.
*Including some distributors, etc.
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Kind Chemical was established in 2019 in The Woodlands, Texas, US, as a global chemical trading company. Their product range comprises 2-ethylhexyl acetate, benzyl alcohol, acetophenone extra, acrylic acid, terpenes, mint oil, Ionone 100%, acetic acid, and basil oil, among others. The chemicals offered have broad applications: as solvents in coatings, preservatives in cosmetics, intermediates in pharmaceuticals, ingredients in adhesives, and components in aromatherapy and flavors. The company caters to the mining, agriculture, flavor and fragrance, personal care, pharmaceutical, CASE, and Oil and Gas industries.
ChemUniverse, Inc. is a privately owned and operated specialty chemical provider that was founded in 2019.They are headquartered in Des Plaines, Illinois. They sell a wide range of chemicals, including amyl benzoate, naphthalene, pyridine, anethole, isoamyl benzoate, and many others which have different purposes. For instance, Amyl benzoate is a flavoring ingredient found in foods and perfumes while Naphthalene is a moth repellent and a component of various industrial solvents. They offer their services to customers looking for specialized or unique products and offer custom synthesis services to produce items that aren't already in their inventory.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
AGROCHEMICALS is a Washingtonville, New York-based manufacturer of natural flavoring and fragrance ingredients founded in 1994. The company specializes in producing esters, alcohols, pyrazines, ketones, and terpenes. These primarily supply clients in the food and beverage, pharmaceutical and cosmetic industries. The company offers research and development services from its state-of-the-art facility, which has received Safe Quality Food (SQF) certifications from the Global Food Safety Initiative over the last six consecutive years. AGROCHEMICALS serves customers across five continents, including client corporations like Givaudan and Firmenich.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | CAMEO Chemicals |
15.7%
|
2 | ChemUniverse, Inc. |
13.7%
|
3 | Junsei Chemical Co.,Ltd. |
13.7%
|
4 | MilliporeSigma |
11.8%
|
5 | AUROCHEMICALS |
9.8%
|
6 | Kind Chemical |
9.8%
|
7 | KANTO CHEMICAL CO.,INC. |
7.8%
|
8 | FooDB |
5.9%
|
9 | Tokyo Chemical Industry Co., Ltd. |
5.9%
|
10 | nacalai |
5.9%
|
Derivation Method
The ranking is calculated based on the click share within the ethyl formate page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 4 | 66.7% |
United States of America | 2 | 33.3% |