19 Caffeine Manufacturers in 2024
This section provides an overview for caffeine as well as their applications and principles. Also, please take a look at the list of 19 caffeine manufacturers and their company rankings. Here are the top-ranked caffeine companies as of November, 2024: 1.Vigon International, 2.Protekt Products, Inc., 3.LIQUID CAFFEINE, INC..
Table of Contents
What Is Caffeine?
Caffeine is a naturally occurring stimulant alkaloid.
It is found primarily in coffee, tea, cocoa, and energy drinks, and may also be added to some drugs and dietary supplements.
Synthetic caffeine is manufactured using urea as a starting material. Natural caffeine can be obtained by extraction from coffee beans or other sources. It is also obtained from the production of decaffeinated coffee.
The effects of caffeine include its effect on the cerebral cortex to eliminate drowsiness, its effect on the heart to dilate the coronary arteries, and its diuretic effect.
Uses of Caffeine
Caffeine has stimulant, antipyretic, analgesic, cardiotonic, and diuretic effects, and is used as a central nervous system stimulant, diuretic, and inotropic agent for angina pectoris and other such ailments. It is also sometimes found in headache and cold medicines due to its cerebral vasoconstrictive effects.
Caffeine is used as a food additive for bitter taste and other uses, and is often added to some soft drinks and foods. It is also used in physiological research and as a raw material for organic synthesis.
It is also used to repel insects, and there are examples of its use in agriculture.
Properties of Caffeine
Caffeine's chemical name is 1,3,7-trimethylxanthine, and it is a white, columnar crystal in appearance. It is soluble in water, ethanol, chloroform, ether, acetone, and benzene, but is insoluble in petroleum ether and ligroin. It has no odor and has a bitter taste.
Caffeine affects the central nervous system, increasing alertness. It is also believed to improve athletic performance and reduce feelings of fatigue. However, excessive intake can cause anxiety, nervousness, and insomnia.
Health studies suggest that in moderate amounts, caffeine has a positive effect on health. However, in excess or in the presence of a pre-existing medical condition, it can have a negative impact on health. Therefore, it is important to observe moderation in the consumption of caffeine.
In particular, pregnant women, lactating women, and those with pre-existing medical conditions such as high blood pressure or irregular heartbeat may need to limit their intake of caffeine. It is important to adjust your caffeine intake according to your doctor's instructions.
Other Information on Caffeine
1. Caffeine Intoxication
Excessive intake of caffeine can cause caffeine overdose. Ingested caffeine affects the central nervous system, causing excessive arousal and excitement, which, depending on the amount consumed and individual sensitivity, such as:
Symptoms of caffeine intoxication include the following:
- Insomnia, nervousness, anxiety, unstable mood
- Increased heart rate, irregular heartbeat
- Gastrointestinal discomfort, nausea, vomiting
- Headache, dizziness, tremors in arms and legs
In severe cases, hallucinations, confusion, convulsions, and difficulty breathing may occur. Caffeine in large doses and over a long period of time can also lead to addiction and chronic health problems.
To prevent caffeine addiction, it is important to know the appropriate amount of caffeine to consume and to adhere to a maximum intake limit. If you feel ill from caffeine intake, try to reduce your intake or cut back on the amount you consume. It is also important to consult a doctor if symptoms are severe or persistent.
2. Effects on the Body
While caffeine can temporarily stop headaches, regular use can increase the likelihood of headaches. This is due to its cerebral vasoconstrictive effects.
3. Dependence and Tolerance
Repeated consumption of caffeine can lead to a mild psychological dependence, which is called caffeine dependence. In addition, the various effects of caffeine diminish with regular consumption, and tolerance develops.
List of 19 Caffeine Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Japan
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Protekt Products, Inc.
Caffeine
Manufacturer Overview
Protekt Products Inc. is a manufacturer of energy supplements and organic sunscreen based in Wyoming, USA. The company offers a range of performance supplements designed to support outdoor enthusiasts and athletes. These supplements include hydration products, energy boosters, immunity support, and other supplements. These products aim to help individuals perform during outdoor activities. Additionally, the company offers sun protection products, including zinc oxide lotions with varying levels of SPF (30 and 50 mineral sunscreen) and zinc oxide sunsticks and balms, which are essential for protecting the skin from harmful UV radiation.
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Vigon International
Caffeine
Manufacturer Overview
Vigon International is headquartered in East Stroudsburg, Pennsylvania, and is a subsidiary of Azelis. The company is a custom manufacturer of fragrances and flavor products used in cosmetics, food processing, and related industries. The company’s compounds originate from dozens of fruits, herbs, and spices grown in regions as diverse as California, Germany, Brazil, and Indonesia. The company’s custom processing capabilities include adding reaction flavors such as Maillard in batches from 1 to 5,000kg, vacuum distillations, essential oil folding and concentration, and emulsion production.
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SAE Manufacturing Specialties Corp
Caffeine
Manufacturer Overview
Based in Bayville, NY, SAE Manufacturing Specialties Corp. is an ISO-certified supplier and manufacturer of industrial equipment, chemicals, components, ordinance, electronics, and systems for industries ranging from aerospace to high tech to law enforcement. Examples of product offerings include raw materials, chemicals, and lubricants for industrial purposes to finished products such as security helmets for law enforcement, and military ordnances. SAE also provides research and development as well as technical support for other companies in similar industries.
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Gemini Pharmaceuticals
Caffeine
Manufacturer Overview
Gemini Pharmaceuticals, established in 1983, and headquartered in Commack, New York, is a manufacturer and supplier of dietary supplements and OTC pharmaceuticals. The company specializes in producing tablets, capsules, powders, and liquids in which their products cater to industries such as nutraceuticals, health and wellness, and the pharmaceutical sector. Gemini Pharmaceuticals ensures quality and compliance, holding certifications such as NSF International GMP and FDA registration and their products are used to promote health, support nutritional needs, and address various wellness concerns in consumers across different markets.
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TRInternational, Inc.
Caffeine
Company Overview
TRInternational Inc., founded in 1994 and headquartered in Edmonds, Washington, is a supplier of ingredients, raw materials, and services in North America. Its diversified product portfolio includes chemicals, rubber, and paints used in industries like metalworking, water treatment, and industrial cleaning. It has over 20 stocking and import points across the United States and offers additional services like custom manufacturing, contract packaging, and proprietary formulation. The company is SBA, WOSB, and LGBTBE certified, and in 2018, it was ranked number 70 in the Top 100 Chemical Distributors in North America.
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The Chemical Co.
Caffeine
Company Overview
The Chemical Company (TCC) was founded in 1988 in Jamestown, Rhode Island. TCC is a distributor of chemicals, composites, and plastics. TCC strategically sources materials to provide customers with secure product supply to ensure longterm supply security. TCC’s product categories include C.A.S.E. (coatings, adhesives, sealants, and elastomers) such as adipic acid and casein, flame retardants such as dicyandiamide and calcium chloride, silanes, acid such as boric acid and citric acid, water treatment such as melatonin and nicotinamide, intermediates such as acetone, fertilizer & crop nutrition such as ammonium sulfate, and polymer additives such as resorcinol and zinc borate.
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Superior Supplement Manufacturing
Caffeine
Company Overview
Superior Supplement mfg firm, established in 2014 and headquartered in California, United States, specializes in various delivery forms and provides services like formulations, research and development, component sourcing, packaging services, printing, label design, and other related offerings. The company manufactures nutritional supplements, that include soft gels, capsules, liquids, gummy tablets, lotions, powders, and different formulations. To package its products, the company utilizes several wrap formats which include sachets, bottles, bags, stick packs, pouches, folder cartons, and blister packs.
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Wego Chemical Group Inc
Caffeine
Distributor Overview
Wego Chemical Group was founded in 1978 and headquartered in Great Neck, New York. WEGO is a full-service supplier and distributor of chemicals, minerals, and other raw materials to clients around the world. Markets and segments include agriculture & animal care, chemical & material manufacturing, construction & building materials, electronics, food & beverage, “household, industrial & institutional”, mining, oil & gas, personal care & pharmaceutical, paper & packaging, surface treatment, textiles, and water treatment.
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Allan Chemical Corporation
Caffeine
Distributor Overview
Allan Chemical Corp., established in 1984, is a distributor of specialty chemicals and raw ingredients such as Acetyl Tributyl Citrate, Ammonium Carbonate, Calcium CHrolide Dihydrate, Caffeine anhydrous powder, and ferrous ammonium sulfate used in ceramics & glass, screen printing, cosmetics & personal care, laboratory industries, food & beverage, and fragrance industries. The company in Margaret King Avenue Ringwood, New Jersey, is ISO 9001 certified, and the products conform to quality standards such as Halal, EP, ACS, FCC, and Kosher.
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KANTO CHEMICAL CO.,INC.
Caffeine, anhydrous
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Junsei Chemical Co.,Ltd.
Caffeine
Manufacturer Overview
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
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Kishida Chemical Co.,Ltd.
Caffeine
Manufacturer Overview
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
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Merck
Caffeine
Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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MilliporeSigma
Caffeine
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Ebrator Biochemicals Inc.
Caffeine
Manufacturer Overview
Ebrator Biochemicals, Inc. is a manufacturer and supplier of fine chemicals and life science materials for use in the pharmaceuticals, biotech, and healthcare industries. Founded in 2018 and based in Santa Ana, California, the company provides various biological stains and dyes, analytical agents, impurities, and DNA cloning materials for applications in diagnostics and scientific research. The company’s specialized product range includes amino acids and carbohydrates, ACS reagents, plasmids and restriction enzymes. Ebrator Biochemicals, Inc. also offers custom synthesis and packaging services for its clients, which include Quest Diagnostic, Pfizer, and Thermo Fisher Scientific.
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CJ Chemicals
Caffeine
Company Overview
CJ Chemicals is headquartered in Howell, Michigan. The company is a distributor and import supplier of the chemicals industry, storing a broach repository of more than 350 different chemicals. The company operates in four segments: warehousing & storage, shipping, import/export, and lab capabilities. Warehousing is done in the company’s warehouse in Toledo, Ohio at its 50,000 square foot facility. Shipping services include LTL and full truckload shipping nationwide. Import/export services serve global customers and suppliers. Lab capabilities including reverse engineering, formulating custom tailored products, technical support, and manufacturing of custom blends.
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Caffeine Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Vigon International |
17.1%
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| 2 | Protekt Products, Inc. |
12.4%
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| 3 | LIQUID CAFFEINE, INC. |
8.2%
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| 4 | Gemini Pharmaceuticals |
7.2%
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| 5 | SAE Manufacturing Specialties Corp |
7.2%
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| 6 | TRInternational, Inc. |
5.9%
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| 7 | The Genius Brand |
5.0%
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| 8 | The Chemical Co. |
5.0%
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| 9 | Allan Chemical Corporation |
4.2%
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| 10 | Superior Supplement Manufacturing |
3.8%
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Derivation Method
The ranking is calculated based on the click share within the caffeine page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
- Kishida Chemical Co.,Ltd.: 283
- Junsei Chemical Co.,Ltd.: 171
Newly Established Company
- TRInternational, Inc.: 1994 (30 years ago)
- The Chemical Co.: 1988 (36 years ago)
- Wego Chemical Group Inc: 1978 (46 years ago)
Company with a History
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- Junsei Chemical Co.,Ltd.: 1948 (76 years ago)
- Wego Chemical Group Inc: 1978 (46 years ago)
Caffeine Manufacturers in United States
*Including some distributors, etc.
- Protekt Products, Inc.
- Vigon International
- SAE Manufacturing Specialties Corp
- Gemini Pharmaceuticals
- TRInternational, Inc.
- The Chemical Co.
- LIQUID CAFFEINE, INC.
- The Genius Brand
- Superior Supplement Manufacturing
- Wego Chemical Group Inc
- Ingredients Online
- Allan Chemical Corporation
Global Distribution of Caffeine Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
12 | 80.0% |
Japan
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3 | 20.0% |
