All Categories
History
This section provides an overview for thermal cyclers as well as their applications and principles. Also, please take a look at the list of 44 thermal cycler manufacturers and their company rankings. Here are the top-ranked thermal cycler companies as of December, 2024: 1.Chai Inc., 2.Siemens Medical Solutions USA, Inc., 3.Manta PC Tools USA Inc.
Table of Contents
A thermal cycler is a laboratory device used to perform the polymerase chain reaction (PCR) method, essential for DNA amplification. It meticulously controls the temperature cycle between approximately 50°C and 100°C, necessary for each step of the PCR process, thereby acting as both a temperature regulator and an incubator.
Thermal cyclers are pivotal for temperature regulation in PCR applications, primarily in molecular biology and medical research fields. The device has transformed PCR into a more efficient process by eliminating the need for manual temperature adjustments and timing measurements that were required before its development.
The core of a thermal cycler is a metal plate with wells, known as a thermal block, designed to hold tubes filled with reaction mixtures. Temperature control programs cause the plate’s temperature to fluctuate, heating or cooling the reaction mixture as needed. Modern thermal cyclers often utilize peltier elements, which offer more efficient temperature regulation by changing the electric current's direction.
Selection of a thermal cycler should consider accuracy in temperature control and uniformity across thermal blocks. Features vary across models:
These allow for independent temperature settings for each block, catering to diverse experimental needs.
Integrating a fluorescence detector, this type facilitates real-time PCR by enabling DNA amplification and quantitative analysis through fluorescence intensity measurement.
Equipped with a heated lid to prevent sample evaporation at high temperatures, thus eliminating the need for mineral oil and streamlining the PCR process.
Modern thermal cyclers feature user-friendly interfaces for program setup and control, accessible via PC or touchscreen, simplifying the automation of temperature control and timing for sample reactions.
PCR is a technique for the amplification of specific DNA sequences, involving cycles of heating and cooling to separate DNA strands, bind primers, and synthesize DNA through enzymatic reactions. Thermal cyclers automate this process, enhancing the efficiency and precision of PCR analysis.
*Including some distributors, etc.
Sort by Features
Sort by Area
Benchmark Scientific, founded in the US in 2004, is a manufacturer and supplier of laboratory equipment used for life scientific research. It provides research laboratories with cost-effective products to enhance efficiency, safety, and results. Company’s product line includes a range of buffet laboratory equipment, such as orbital/rocking, incubated shakers, hotplates-stirrers/magnetic stirrers/overhead stirrers, and more. It also offers incubators, scales/balances, thermal cyclers, cell counters, and other instruments. With an emphasis on technology, Benchmark Scientific aims to support scientific advancements and improve laboratory practices.
SPEX SamplePrep, established in 1954 and headquartered in Metuchen, NJ, USA, is a manufacturer of certified reference materials (CRMs) and calibration standards. The company offers a comprehensive range of products, such as a Geno/grinder, MiniG, and freezer/mill for various applications, including geology, forensics, and pharmaceuticals. Its equipment is utilized for sample preparation in analytical technologies like XRF, ICP, and PCR. It has been employed in significant studies such as NASA's moon rock analysis and identifying Czar Nicholas II's remains. The company's cryogenic mills, homogenizers, and presses are practical and are supported by service and expertise.
Siemens Healthineers USA (formerly known as Siemens Medical Solutions USA, Inc.), founded in 1847 and a subsidiary of Siemens Healthineers, is a manufacturer based in Malvern, Pennsylvania, specializing in healthcare solutions and services. The company’s portfolio includes a range of medical and diagnostic imaging equipment and machinery. It also provides products and services for laboratory diagnostics, including assays, automation, testing systems, and educational resources. Moreover, the company offers therapeutic concepts and minimally invasive procedures for clinical conditions. The company also offers value partnerships, aiding enterprises in enhancing performance and achieving healthcare targets, along with consulting services facilitated by ECG Management Consultants.
Chai Inc. is a not-for-profit American manufacturer of polymerase chain reaction (PCR) and real-time PCR (qPCR) instruments that was established in 2013 in Santa Clara, California. The company’s specialized product lineup includes PCR master mixes for producing repeatable PCR test results, qPCR thermocyclers for detecting DNA, COVID saliva-based testing kits, and DNA as well as RNA extraction buffers. It also offers beer spoilage testing kits, along with selective and differential media for identifying beer spoilage microorganisms. The company’s products are commonly used in biotech, life sciences, and private security, as well as in micro-, craft, and large beer breweries.
Corning Incorporated, founded in 1851 and headquartered in Corning, New York, is a manufacturer and supplier of specialty glass, ceramics, and optical fiber. Their offerings include optical fiber for long-distance light signal transmission, specialty glass for applications like displays and lighting, ceramics for various uses, such as cookware and medical implants, and advanced materials like 3D printing powders and ceramic matrix composites. Additionally, Corning provides products for the life sciences industry, such as labware, consumables, and analytical instruments.
Eppendorf, founded in 1945 with headquarters in Germany, is a manufacturer and supplier of laboratory equipment, instruments, and consumables. The company's product line includes pipettes, pipette tips, centrifuges, mixers, and ultra-low-temperature equipment. Eppendorf's products are used in academic and commercial research laboratories as well as in the pharmaceutical, biotechnical, chemical, and food industries to perform clinical, environmental, process analysis, and production quality assurance. The company also offers services for liquid, sample, and cell handling in laboratories worldwide.
Bio-Rad Laboratories, Inc., founded in 1952, is an American manufacturer headquartered in Hercules, California, specialized in technological products for the life science research and clinical diagnostics markets. The company's portfolio includes life science products such as chromatography, polymerase chain reaction (PCR), and flow cytometry antibodies. In the clinical diagnostics domain, the company provides liquid chromatography (HPLC) solutions for diabetes testing, along with automation tools for hospitals and clinical core laboratories. The company also offers quality control products for laboratory quality management system as well as food and beverage testing. Notably, services offered include laboratory setup, instrument maintenance, and educational programs.
Bulldog-Bio, started in 2009 and based in Portsmouth, New Hampshire, is a distributor of reagents, instruments, and tools to life science researchers in North America. It stocks antibody reagents, benchtop shakers, cellular analysis tools, cell culture reagents, and electrophoresis products. However, it has some products that it considers to be essential, including TaqDog Polymerases and Master Mixes, BamBanker Cell Freezing Media, GeneExplorer Thermal Cyclers, Electroporation Cuvettes, and Midori Green Nucleic Acid Staining Solution. The company works with several manufacturers and suppliers worldwide, including Q Instruments, N-Zyme Scientific, iNtRON Biotechnology, Nippon Genetics Europe, and CleanNA.
Thermo Fisher Scientific Inc., founded in 1956 and headquartered in Waltham, Massachusetts, is a manufacturer and supplier of life science solutions, analytical instruments, specialty diagnostics, laboratory products, and biopharma services. Through its brand names, including Invitrogen, Fisher Scientific, Patheon, Applied Biosystems, and Gibco, among others, the company provides a wide range of products, which include chromatography systems, thermal cyclers, automated cell counters, fermenters, and DNA polymerases. The company’s annual revenue is over 40 billion USD, and it serves several fields, including customers working in clinical diagnostic labs, research institutions, hospitals, government agencies, and pharmaceutical/biotech companies.
LGC Biosearch Technology, established in 1993 and is based in Middlesex, UK, is a manufacturer of oligonucleotide-based tools. The company's product portfolio includes isothermal amplification, RNA FISH, oligos, probes and primers that are applied in health care and applied market segments. It also offers a vast portfolio of services like biobanking, sequencing, genotyping and OEM kit assembly. The company's reagents and other components were used in COVID-19 test kits worldwide during the pandemic.
Shenyang Yu Shuo Da Science And Technology Ltd., established in 2016, is a Chinese manufacturer based in Shenyang, Liaoning, providing laboratory equipment and consumables. The company’s laboratory equipment lineup includes autoclave sterilization equipment, centrifuges, and embedding centers. The company also offers laboratory consumables, including pathology histology and biological cytology products. Medical refrigerators are also available, ranging from 50 liters up to 1,000 liters, commonly used in laboratories, pharmacies, hospitals, and blood banks. The company further expands its offerings to include stainless steel veterinary equipment, such as animal cages and surgical tables, along with mortuary products like autopsy tables and mortuary freezers.
OLABO, established in 2012, is a manufacturer and supplier specializing in laboratory and scientific equipment based in Shandong, China. The company offers a wide range of laboratory equipment, including cleaning and disinfection equipment, safety protection products, medical equipment, and analytical tools. Their product portfolio also includes cold chain products and some industry research equipment. OLABO adheres to ISO13485, ISO9001, and CE certifications and maintains research, quality control, sales, and after-sales service teams to serve their clients across the globe.
RWD Life Science Co., Ltd., established in 2002 in Shenzhen, China, is a manufacturer of unique laboratory and life science research equipment. The company’s product line includes laboratory instruments, imaging systems, and analysis software for applications in the fields of cell biology, molecular biology, and drug discovery. These products offer advanced features, optimal accuracy, and user-friendly interfaces, enhancing research productivity and enabling scientists to achieve precise results. These tools find applications in academic research, pharmaceutical companies, and biotechnology laboratories. These solutions assist researchers and scientists looking to advance their understanding of biological processes and develop new therapies.
Esco Micro Pte. Ltd., founded in 1978 and based in Singapore, is a manufacturer and service provider of life science tools. Its products include air showers, animal research workstations, anti-vibration tables, bioreactors, cell harvesting systems and more. As a manufacturer of biopharma and laboratory equipment, and IVF medical devices, the company provides solutions to laboratories in various industries. Esco has direct sales and service outlets in more than 21 countries. It owns eight manufacturing and R&D centers in China, the US, Europe, and the UK. It delivers its products to more than100 countries.
Xi'an TianLong Science and Technology Co., Ltd. is a Chinese manufacturer of nucleic acid testing reagents and instruments established in 1997 and based in Wuxi, Jiangsu. The company produces various PCR thermal cyclers, nucleic acid extractors, automatic nucleic acid workstations, and all-in-one molecular diagnosis systems. Its products are used for pathogen detection, life science research, medical diagnostics, and food safety testing. Aside from its own products, the company also offers OEM/ODM services for clients with unique project requirements.
Blue-Ray Biotech Corp. is a Taiwanese manufacturer of life science equipment and instruments established in 1981 and based in New Taipei City. The company produces various UV–visible (UV/Vis) spectrophotometers, PCR thermal cyclers, live cell imaging devices, microcentrifuges, and PCR reagents. These are primarily used in biotechnology research done in laboratories and educational institutions, but also have applications in clinical diagnostic procedures, food safety testing, pharmaceutical development, and environmental testing. The company also offers additional technical support, as well as an Extended Care Program which includes on-site qualification services, calibration, and an extended warranty.
Analytik Jena GmbH, established in 1990 and headquartered in Jena, Germany, is a manufacturer and supplier of analytical and scientific instruments. They offer a range of products, including spectrophotometers, liquid handling systems, PCR devices, thermal cyclers, and laboratory automation solutions. Analytik Jena serves diverse industries, such as life sciences, pharmaceuticals, biotechnology, environmental analysis, and food testing, utilized for research, quality control, diagnostics, and monitoring applications. Analytik Jena GmbH+Co. KG operates in compliance with the DIN EN ISO 9001 standard.
LabGeni is a manufacturer and supplier of laboratory equipment and consumables that was established in 2004 and is headquartered in Wuhan, China. LabGeni's main activity is the design, development, and manufacturing of laboratory equipment, including microplate readers, centrifuges, and incubators. The company also offers a wide range of laboratory consumables, such as pipette tips, microcentrifuge tubes, and cell culture media. Its products are used by a wide range of customers, including academic institutions, research laboratories, and pharmaceutical companies. LabGeni has over 200 employees and operates in more than 20 countries.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Industrial Heating & Cooling GmbH, founded in Germany, is a supplier of automated liquid handling platforms. The company's customers include major manufacturers, integrators, and end-users in big pharma, biotech, diagnostics research, and academia. The company is ISO 9001:2015 certified for consulting, development, manufacturing, sales, and support of lab automation products. Its product portfolio includes thermal cycling, cell incubation, incubating and shaking, adapter plates, and custom adapters and it also offers rental options for equipment.
Ningbo Scientz Biotechnology Co.,Ltd, founded in 1989 and based in Zhejiang, China is a manufacturer and supplier of ultrasonic apparatus and laboratory & scientific instruments. The company’s product portfolio is composed of melting furnaces, multi-block thermal cyclers, ultrasonic homogenizers, high-speed dispersator, and laboratory equipment such as spectrophotometers, centrifuges, microscopes, dry bath incubators, and rotary evaporators. They have completed the ISO 9001 certification and their products are used in industrial, pharmaceutical, environmental protection, research institutes, and hospital applications.
Nanbei Instrument Limited, started in 2008 in Zhengzhou, China, is a manufacturer and supplier of chemical, laboratory, geological, agricultural and test instruments used in these industries: metallurgical mines, roads and bridges, research institutes, and agriculture. The research products the company makes includes rotary evaporators, atomic absorption spectrophotometers, seed quality analyzers, chemical analysis equipment and laboratory thermostats. It has received the SO 9001:2015 quality management system, CE of Trademark, CE of EU Trademark, Medical Type-2 Reports and EU of CE certifications.
Ajanta Export Industries, established in 1957 and based in Haryana, India, is a manufacturer, supplier, and distributor of scientific laboratory equipment. The company offers other products such as soil equipment, survey equipment, surgical microscope, slit lamp, and laboratory glassware. All of them are manufactured with high-grade components and used in physics, chemistry, and biology labs worldwide. The company abides by the quality standards and produces the products that meet these standards. Every product made is tested in the equipped testing facilities.
Takara Bio Inc., established in 1925, is a manufacturer and distributor of life science reagents based in Shiga, Japan. The company's service portfolio includes sequencing, stem cell research, gene function, cloning and PCR applied in vaccine development, reproductive health, molecular diagnostics, cancer research and pathogen detection. Takara Bio’s products fall under three brands, namely Takara, Clontech and Cellartis, each with its area of expertise. The company also offers research classes through webinars, technical notes and other informational resources and has business operations in the USA, China, Korea, Europe and India.
Kalstein France, founded in 1944 and located in Paris, France, is a manufacturer and supplier of laboratory equipment. The company offers products such as spectrophotometers, thermal cyclers, and vacuum drying ovens. It mainly manufactures these products for the dental, industrial, and medical sectors, and also offers professional advice in these fields. The company also provides customized solutions, serving the pharmaceutical and veterinary industries. It provides post-sales technical support, online training, and quality control services.
Axiva Sichem Biotech, established in 2000 and based in Delhi, India, is a manufacturer and supplier of lab filtration products. The company's product range includes Lab Filtration, Lab Plasticware, Lab Glassware, Safety Products, and Chromatography Consumables. These products are essential for various laboratory processes and experiments. They primarily serve industries and research facilities focused on precision and quality in laboratory settings. Axiva Sichem Biotech provides services such as technical application support, after-sales service, equipment maintenance, and product development.
BIOBASE, established in 1999, is a high-tech manufacturing enterprise whose business covers biomedical, e-commerce, intelligent manufacturing, scientific equipment In Vitro Diagnosis (IVD) instrument and reagent based in China. Specialized in research, development, and manufacturing of laboratory and medical equipment, catering to life sciences, healthcare, and environmental protection industries. Their product range includes biological safety cabinets, incubators, centrifuges, and more. The company has branch offices in 24 provinces in China, with overseas establishment in USA, Dubai, India, Algeria, Singapore, and business partners in 130 countries.
QIAGEN, founded in 1986 with its headquarters in Venlo, the Netherlands, is a provider and supplier of molecular testing and insight solutions. The company's assay and sample technologies help clients gain valuable insights into the building blocks of life. Its sample technologies process and separate DNA and RNA from tissue, blood, and other substances. Its assay technologies prepare these biomolecules for analysis. Its bioinformatics software analyzes and interprets molecular data, giving actionable insights while automation solutions integrate them together for seamless execution of workflows. The company's clients are those involved in human healthcare, academia, food safety, pharmaceutical, and biotechnology research.
Labnet, since 1984, is a supplier of laboratory and constant temperature equipment and accessories such as centrifuges, liquid handling equipment, lab shakers & rockers, incubators, and plasticware. The company headquarters are in Edison, NJ, USA offers OEM applications to clients in Clinical Diagnostics, Industrial Testing, Molecular Biology, and Pharmaceuticals. Brands they work with include Spectrafuge, MultiGene BioPette, AccuBlock, and Enduro. The liquid handling equipment includes pipet tips & controllers, manual & electric pipettors, and repeating pipettors with Combi-syringes.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Chai Inc. |
5.8%
|
| 2 | Siemens Medical Solutions USA, Inc. |
5.8%
|
| 3 | Manta PC Tools USA Inc |
5.2%
|
| 4 | Benchmark scientific |
5.2%
|
| 5 | Corning Incorporated |
5.2%
|
| 6 | Eden |
4.5%
|
| 7 | Cole-Parmer |
3.9%
|
| 8 | Bulldog-Bio inc. |
3.9%
|
| 9 | MAXFLO |
3.2%
|
| 10 | Foregene Co., Ltd. |
3.2%
|
Derivation Method
The ranking is calculated based on the click share within the thermal cycler page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
12 | 33.3% |
|
China
|
12 | 33.3% |
|
India
|
5 | 13.9% |
|
Germany
|
2 | 5.6% |
|
United Kingdom
|
1 | 2.8% |
|
Singapore
|
1 | 2.8% |
|
Taiwan
|
1 | 2.8% |
|
Japan
|
1 | 2.8% |
|
France
|
1 | 2.8% |
35 products found
35 products
Ibic Research Co., Ltd.
30+ people viewing
Last viewed: 1 day ago
Standard Response
On-deck thermal cycler Equipped with excellent thermal properties and new VCM technology. The most compact endpoint PCR cycler for automated liquid...
Yagyu Shokai Co., Ltd.
50+ people viewing
Very Fast Response
■New compact and easy-to-install high-performance real-time PCR thermal cycler 1.Small, lightweight and stylish design that can be placed anywhere....
Yagyu Shokai Co., Ltd.
30+ people viewing
Last viewed: 10 hours ago
Very Fast Response
■High-end thermal cycler equipped with 2D gradient function is now available Equipped with 1.2D gradient function, greatly reducing experiment time...
Yagyu Shokai Co., Ltd.
30+ people viewing
Last viewed: 9 hours ago
Very Fast Response
-Equipped with an easy-to-read 7-inch color touch panel for intuitive operation. - Programs can be easily set by following the on-screen instructio...
Yagyu Shokai Co., Ltd.
20+ people viewing
Last viewed: 22 hours ago
Very Fast Response
・It is a small, lightweight product that achieves accurate and fast temperature control. - Equipped with a 5-inch color touch panel for intuitive ...
Yagyu Shokai Co., Ltd.
30+ people viewing
Last viewed: 9 hours ago
Very Fast Response
■Features ・A compact thermal cycler that makes PCR experiments easy. - USB connection allows you to create and save protocols and monitor operatin...
10+ people viewing
Last viewed: 1 day ago
■New compact thermal cycler with stable temperature control function and high operability Takara Bio's Clontech PCR Thermal Cycler GP is a compact ...
10+ people viewing
Last viewed: 2 hours ago
■High performance at a reasonable price Biometra TOne 96/96G is a reasonably priced 96well x 0.2mL thermal cycler. High heating rate of 4℃/s provid...
10+ people viewing
Last viewed: 8 hours ago
■New twin block model released from Biometra. Two blocks can be operated separately. Ideal for laboratories with a large number of users. The Biome...
10+ people viewing
■Premium quality next-generation thermal cycler that leverages 25 years of experience and know-how Biometra TAdvanced Thermal Cycler is available i...
20+ people viewing
■3-block multi-model thermal cycler that can be operated independently The BiometraTRIO thermal cycler is the only device with three separate block...
10+ people viewing
■The latest model that inherits the technology of the qTOWER3 series and is even more advanced. The qTOWER3 iris series is a 96well or 384well form...
20+ people viewing
Last viewed: 3 hours ago
■High-performance multicolor real-time PCR device This multicolor real-time PCR device is equipped with an excellent temperature control system and...
Astec Co., Ltd.
450+ people viewing
Last viewed: 40 minutes ago
■ Product points Thermal Cycla GENEATLAS is a domestic machine with excellent performance ・ Accurate temperature control ・ High operability and v...
4 models listed
Astec Co., Ltd.
160+ people viewing
Last viewed: 7 hours ago
■ Fixed block type with excellent cost performance Renewed while maintaining excellent operability, performance and function ■ Features -The heati...
2 models listed
Astec Co., Ltd.
170+ people viewing
Last viewed: 1 day ago
Fixed block type optimal for small volume samples ■ Features ・ Provided at reasonable prices ・ 5.5 inch wide LCD screen ・ Heating block cover ...
2 models listed
Astec Co., Ltd.
210+ people viewing
Last viewed: 22 hours ago
The Thermal Cycle E Series is a standard model that supports the 96WELL plate that emphasizes cost performance and the 0.5ml tube. ■ Product point...
2 models listed
Eppendorf North America
70+ people viewing
Last viewed: 7 hours ago
■Product features ・Heating rate: 10℃/sec (Silver block model) ・Easy programming with touch panel operation ・Excellent temperature control accura...
Eppendorf North America
70+ people viewing
Last viewed: 7 hours ago
■Product features ・Heating rate: 10℃/sec (Silver block model) ・Easy programming with touch panel operation ・Excellent temperature control accura...
Eppendorf North America
60+ people viewing
Last viewed: 5 hours ago
■Product features ・Heating rate: 10℃/sec (Silver block model) ・Easy programming with touch panel operation ・Excellent temperature control accura...
Eppendorf North America
90+ people viewing
Last viewed: 7 hours ago
■Product features ・Precise temperature control: ±0.2℃ ・You can select a model with 12-step gradient function ・Expansion-only models are also ava...
Eppendorf North America
70+ people viewing
Last viewed: 1 hour ago
■Product features ・Heating rate: 10℃/sec (Silver block model) ・Easy programming with touch panel operation ・Excellent temperature control accura...
Eppendorf North America
70+ people viewing
Last viewed: 14 hours ago
■Product features ・Precise temperature control: ±0.2℃ ・You can select a model with 12-step gradient function ・Expansion-only models are also ava...
Eppendorf North America
80+ people viewing
Last viewed: 11 minutes ago
■Product features ・Precise temperature control: ±0.2℃ ・You can select a model with 12-step gradient function ・Expansion-only models are also ava...
Eppendorf North America
80+ people viewing
Last viewed: 14 hours ago
■Product features ・Precise temperature control: ±0.2℃ ・You can select a model with 12-step gradient function ・Expansion-only models are also ava...
Eppendorf North America
60+ people viewing
Last viewed: 11 minutes ago
■Product features ・Precise temperature control: ±0.2℃ ・You can select a model with 12-step gradient function ・Expansion-only models are also ava...
Eppendorf North America
60+ people viewing
Last viewed: 6 hours ago
■Product features ・Precise temperature control: ±0.2℃ ・You can select a model with 12-step gradient function ・Expansion-only models are also ava...
Eppendorf North America
90+ people viewing
Last viewed: 6 hours ago
■Product features ・Precise temperature control: ±0.2℃ ・You can select a model with 12-step gradient function ・Expansion-only models are also ava...
