10 Guanosine Manufacturers in 2024
This section provides an overview for guanosine as well as their applications and principles. Also, please take a look at the list of 10 guanosine manufacturers and their company rankings. Here are the top-ranked guanosine companies as of April, 2024: 1.Chemodex Ltd., 2.Manus Aktteva Biopharma LLP, 3.Hefei Home Sunshine Pharmaceutical Technology Co., Ltd..
Table of Contents
What Is Guanosine?
Guanosine is a nucleoside formed by the combination of guanine and ribose, a monosaccharide, connected via a β-N9-glycosidic bond.
Nucleosides, such as guanosine, encompass compounds comprising a base and sugar, including adenosine, uridine, thymidine, and cytidine, among others. Guanosine, with the IUPAC name 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-one, is also known as guanine riboside, with abbreviations G or Guo.
Uses of Guanosine
Guanosine derivatives serve as crucial nucleic acid-related reagents. Through multiple phosphorylation steps, guanosine transforms into guanylic acid (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP).
These phosphorylated guanosines play pivotal roles in various biochemical processes, including nucleic acid and protein synthesis, photosynthesis, muscle contraction, and intracellular signal transduction. Notably, GTP interacts with diverse proteins, regulating biochemical reactions; proteins binding to GTP are termed GTP-binding proteins.
For instance, GTP-binding proteins influence cell division initiation: activation prompts cell division, while inactivation halts it. Dysregulation, where abnormal GTP-binding proteins remain activated, can lead to uncontrolled cell division, known as "oncogenesis".
Properties of Guanosine
With a chemical formula of C10H13N5O5 and a molecular weight of 283.24, guanosine, registered under CAS number 118-00-3, appears as a white, odorless, crystalline powder at room temperature, forming needle-like crystals.
It exhibits solubility in acetic acid but remains insoluble in organic solvents like ethanol, diethyl ether, benzene, and chloroform. Solubility in water reaches approximately 700 mg/L at 18°C.
Guanosine undergoes hydrolysis under acidic conditions, yielding guanine and ribose. Additionally, treating guanosine with nitrite produces xanthosine.
Other Information on Guanosine
1. Production of Guanosine
Guanosine naturally occurs in the pancreas, clover, coffee trees, and pine pollen. Alternatively, enzymatic dephosphorylation of guanylic acid, derived from RNA hydrolysis under basic conditions, synthesizes guanosine.
2. Handling and Storage Precautions
Handling Precautions
Exercise caution to avoid contact with oxidants during handling and storage. Utilize appropriate protective gear, including gloves, goggles with side shields, and long-sleeved clothing, while working in a well-ventilated area. Wear a dust mask if necessary and wash hands thoroughly after use.
In Case of Fire
In the event of combustion, carbon monoxide (CO) and nitrogen oxides (NOx) may form. Move the chemical to a safe location if feasible; otherwise, cool it with water while wearing protective gear. Employ water spray, powder, carbon dioxide, dry sand, or foam to extinguish the fire.
In Case of Skin Contact
Upon skin contact, remove contaminated clothing and rinse the affected area with copious amounts of water and soap. Seek medical attention if irritation persists.
In Case of Eye Contact
If guanosine enters the eyes, flush with water for at least 15 minutes, avoiding eye injury, and seek immediate medical assistance.
Storage Guidelines
Store guanosine in a cool, dark location in a sealed glass, fluoroplastic, or polyethylene container. Secure the storage area.
List of 10 Guanosine Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- China
- India
- Japan
- Switzerland
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Santa Cruz Biotechnology, Inc.
Guanosine
Company Overview
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
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KANTO CHEMICAL CO.,INC.
Guanosine
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Hefei Home Sunshine Pharmaceutical Technology Co., Ltd.
Guanosine
Manufacturer Overview
Hefei Home Sunshine Pharmaceutical Technology Co., Ltd, established in 2013 and headquartered in Hefei City, China, is a manufacturer specializing in both standard and custom chemical synthesis. With manufacturing facilities in Anhui, Jiangsu, Zhejiang, and Inner Mongolia, Home Sunshine Pharma offers a range of products, including active pharmaceutical ingredients (APIs), intermediates, fine chemicals, coenzymes, and nucleotides. As an ISO 9001:2015 certified company, Home Sunshine Pharma serves research institutions, universities, and industries in Europe, America, and Southeast Asia with their chemical products.
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Manus Aktteva Biopharma LLP
Guanosine
Manufacturer Overview
Manus Aktteva Biopharma LLP, established in 2010 and headquartered in Ahmedabad, India, is a manufacturer, supplier, and exporter of pharmaceutical APIs, intermediates, and specialty chemicals. Their wide-ranging products cater to industries such as pharmaceutical, nutraceutical, and biotechnology. They offer Active Pharmaceutical Ingredients (APIs), the fundamental components used in various drug formulations, such as antibiotics, cardiovascular drugs, and anti-inflammatory drugs. The company also supplies specialty chemicals with unique properties applicable to diverse industries, from plastics to cosmetics manufacturing. Furthermore, the company offers custom synthesis services to meet the specific needs of their customers.
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Chemodex Ltd.
Guanosine
Manufacturer Overview
Chemodex Ltd., established in 2001 and based in St. Gallen, Switzerland, is a manufacturer of fine chemicals, covering different fields such as reagents for life sciences, bioactive molecules, and organic pollutants. The company offers a range of products including fluorescent substances derived from fluorophores such as coumarin, rhodamine, and pyrene. These products are typically used as probes, stains, and in other applications by life-science researchers in academia, biotechnology, and the pharmaceutical industry. Its customer base includes small and medium businesses, large enterprises, as well as academic institutions.
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MilliporeSigma
Guanosine
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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SUVCHEM
Guanosine
Manufacturer Overview
SUVCHEM, established in 2004 and headquartered in Mumbai, India, is a manufacturer and exporter of laboratory chemicals and reagents. Their diverse product range includes organic and inorganic chemicals utilized in pharmaceuticals, plastics, water treatment, and more. They also offer biological stains and indicators for laboratory applications like cell culture and DNA analysis, along with culture media ingredients for growing microorganisms. SUVCHEM's products cater to schools, colleges, research laboratories, pharmaceutical and chemical companies, and other industries, supporting teaching, research, product development, and manufacturing processes across various sectors.
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Fengchen Group Co.,Ltd
Guanosine
Manufacturer Overview
Fengchen Group Co., LTD is based in Qingdao, China. The company is a manufacturer and supplier of speciality chemicals for several industries around the world including natural resources, hydrogeology, drilling, geophysics, and environmental & geotechnical services. The company’s chemical product categories include APIs, amino acids, micronutrients, package materials, and enzymes. The company also offers services including specialized transportation, samples of compounds, shipping documents needed for pharmaceutical products, and international customs support.
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Central Drug House
Guanosine
Company Overview
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
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Vizag Chemical International
Guanosine
Company Overview
Vizag Chemical International was founded in Andhra Pradesh, India, in 2011. Vizag Chemical International sells chemical-based products for many sectors including automotive, agriculture, airline, deodorizers, construction chemicals, boat maintenance, degreasers, detergents, drain clean products, greases, personal hygiene, lab chemicals and equipment, fuel treatment, metal treatment, tank cleaners, swimming pool and spa chemicals, scale removers, sewage chemical treatment, as well as raw chemicals. Vizag Chemical International also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
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Guanosine Manufacturer Ranking
*Including some distributors, etc.Ranking as of April 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Chemodex Ltd. |
18.2%
|
| 2 | Manus Aktteva Biopharma LLP |
18.2%
|
| 3 | Hefei Home Sunshine Pharmaceutical Technology Co., Ltd. |
18.2%
|
| 4 | SUVCHEM |
9.1%
|
| 5 | Fengchen Group Co.,Ltd |
9.1%
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| 6 | Vizag Chemical International |
9.1%
|
| 7 | Central Drug House |
9.1%
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| 8 | KANTO CHEMICAL CO.,INC. |
9.1%
|
Derivation Method
The ranking is calculated based on the click share within the guanosine page as of April 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
Newly Established Company
- Hefei Home Sunshine Pharmaceutical Technology Co., Ltd.: 2013 (11 years ago)
- Fengchen Group Co.,Ltd: 2009 (15 years ago)
- Chemodex Ltd.: 2001 (23 years ago)
Company with a History
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- Chemodex Ltd.: 2001 (23 years ago)
- Fengchen Group Co.,Ltd: 2009 (15 years ago)
Guanosine Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Guanosine Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
India
|
2 | 33.3% |
United States of America
|
1 | 16.7% |
Japan
|
1 | 16.7% |
China
|
1 | 16.7% |
Switzerland
|
1 | 16.7% |
