This section provides an overview for diethyl ether as well as their applications and principles. Also, please take a look at the list of 8 diethyl ether manufacturers and their company rankings. Here are the top-ranked diethyl ether companies as of November, 2024: 1.Shri Rajaram Chemicals & Engg, 2.Junsei Chemical Co.,Ltd., 3.Kishida Chemical Co.,Ltd..
Table of Contents
Diethyl Ether is a compound consisting of two ethyl groups joined by oxygen. It is sometimes called ethyl ether or simply ether. In its IUPAC name, it is also called ethoxyethane.
Diethyl Ether is a light, volatile liquid with a specific odor. It is gradually oxidized in air to form dangerous peroxides. It has an extremely low flash point, so care must be taken when handling it.
Diethyl Ether is used as an analytical reagent, a raw material for organic synthesis, an organic solvent for resins, rubber, fats, oils, and fragrances, and as a fuel. It has a low boiling point among organic solvents, so it can be easily removed from reaction systems when used in organic synthesis.
Diethyl Ether is also used in many other pharmaceutical applications, primarily in inhalation anesthetics. It is also used in the extraction separation of certain metal chlorides from hydrochloric acid solutions.
Diethyl Ether has a low flash point of 160°C. It has a high cetane number of 85-96 and can be used as a combustion aid in diesel engines.
Diethyl Ether has a melting point of -116.3°C and a boiling point of 34.6°C. It is extremely soluble in ethanol, benzene, and chloroform, and somewhat soluble in water.
Diethyl Ether is oxidized by atmospheric oxygen and direct sunlight to form the explosive peroxide diethyl ether peroxides. Therefore, a small amount of dibutyl hydroxytoluene (BHT) may be added as an antioxidant.
Diethyl Ether is an organic compound with a molecular structure consisting of two ethyl groups connected by an ether bond. The specific formula is CH3CH2OCH2CH3 or (CH3CH2)2O. It has a molecular weight of 74.12 and a density of 0.708 g/cm3.
Industrially, diethyl ether is obtained as a byproduct of the synthesis of ethanol from ethene. It can also be synthesized by vapor phase dehydration of ethanol using alumina as a catalyst.
Diethyl Ether can also be synthesized by dehydration-condensation of ethanol using an acid as a catalyst. First, ethanol is mixed with a strong acid such as sulfuric acid, which dissociates to form hydronium ions. The hydronium ion protonates the oxygen atom of ethanol, giving the ethanol molecule a positive charge. The oxygen atom of the unprotonated ethanol molecule is replaced by the water molecule of the protonated ethanol molecule, and diethyl ether can be formed.
However, since the reaction is reversible, diethyl ether must be distilled from the reaction system to increase the yield of diethyl ether. In addition, if the temperature is high, ethanol will dehydrate to ethylene, so the reaction is usually carried out at 150°C or lower.
The metabolism of diethyl ether is thought to involve cytochrome P450, a general term for oxidoreductase. Diethyl ether is O-deethylated by cytochrome P450, yielding ethanol and acetaldehyde.
Diethyl Ether has been used in the past as an alternative to ethanol for drinking. However, it is several times more orally toxic than ethanol, with a minimum lethal dose in humans of 260 mg/kg.
Diethyl Ether has a flash point of -45°C and is extremely flammable. Because of its high insulating properties, it is prone to static electricity, which can cause it to ignite by spark discharge. Note that because diethyl ether has a low flash point, it can be easily ignited by hot utensils even in the absence of flames or sparks.
*Including some distributors, etc.
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Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Shri Rajaram Chemicals & Engg, founded in Pune, Maharashtra, in 2011 is a manufacturer and supplier of Pharmaceutical Chemicals, Fine Chemicals, Laboratory Chemicals & Agricultural Goods. The company's product portfolio includes Fresh Ginger, Dry Ginger Dimethyl Isosorbide, Anthrone, Thiomalic Acid and N-(1-Naphthyl)-Ethylenediamine Dihydrochloride. Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and healthcare. They export to Europe, America, Africa, the Middle East and Australia.
Standard Reagents Pvt. Ltd., founded in 2000, is an Indian chemical manufacturer based in Hyderabad, Telangana. The company offers a wide range of chemicals, encompassing analytical reagents (AR) grade and laboratory reagent (LR) grade chemicals, excipients, gas chromatography (GC) solvents, high-performance liquid chromatography (HPLC) and spectroscopy grade solvents, as well as HPLC gradient solvents. Additional offerings include buffer salts, dry solvents, high-purity acids, HPLC grade acids, and ion-pair reagents. Karl-Fischer reagents (KFR) (pyridine-free single solution) and liquid chromatography (LC) with mass spectrometry (MS) are also available. These chemical products find applications in various industries, such as cosmetics, environment, food, biopharmaceuticals, and pharmaceuticals.
RX Chemicals was founded in Mumbai, India, in 2011. RX Chemicals sells chemical-based products for many sectors including automobile, agriculture, airline, detergents, drain cleaning products, electrical gear, floor care, fuel treatment, gasses, personal care, laundry chemicals, medicine, oil spill chemicals, and accessories, as well as tools. RX Chemicals also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning. The company sells to customers both in India and customers internationally.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Shri Rajaram Chemicals & Engg |
24.5%
|
2 | Junsei Chemical Co.,Ltd. |
24.5%
|
3 | Kishida Chemical Co.,Ltd. |
17.6%
|
4 | RX Chemicals |
12.7%
|
5 | Standard Reagents Pvt. Ltd. |
8.8%
|
6 | Otto Chemie Pvt. Ltd |
5.9%
|
7 | Central Drug House |
3.9%
|
8 | NATIONAL ANALYTICAL CORPORATION |
2.0%
|
Derivation Method
The ranking is calculated based on the click share within the diethyl ether page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
India | 5 | 71.4% |
Japan | 2 | 28.6% |