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This section provides an overview for cytidine as well as their applications and principles. Also, please take a look at the list of 18 cytidine manufacturers and their company rankings. Here are the top-ranked cytidine companies as of December, 2024: 1.SUVCHEM, 2.ChemScence, 3.Central Drug House.
Table of Contents
Cytidine is a nucleoside composed of the pyrimidine base cytosine bonded glycosidically to the 5th carbon of ribose. Cytosine is one of the four bases in DNA, and when bonded to ribose, it forms a nucleoside. These nucleosides join with phosphate and other compounds to construct DNA. In RNA, cytidine corresponds to uracil and is involved in processes like transcription, translation, cell division, and proliferation. It has been reported to inhibit the growth of cancer cells. When nitrite is applied to cytidine, uridine is produced.
Cytidine is soluble in water, alcohol, and organic solvents like acetone, dimethyl sulfoxide (DMSO), diethyl ether, and chloroform. It is stable under normal conditions but more susceptible to degradation in acidic environments due to its basic nature.
Cytidine is a nucleoside with a nitrogen-containing pyrimidine base, cytosine, attached to the 5-position carbon of ribose. It exhibits weak basicity due to a negative charge on the nitrogen atom and can be hydrolyzed by acids.
Cytidine is synthesized intracellularly but industrially produced mainly through chemical synthesis, where cytosine reacts with ribose under basic conditions. Biochemical methods using microorganisms like yeast and bacteria exist but are more common in research than industrial applications due to the complex mixture produced.
*Including some distributors, etc.
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MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
ChemScence, LLC., established in 2006, is an American manufacturer based in Monmouth Junction, New Jersey, specializing in building blocks and fine research chemicals. The company offers approximately 45,000 building blocks and intermediates, as well as thin layer chromatography, screening libraries, bioactive small molecules, and isotope compounds. ChemScence also provides dye and biochemical assay reagents, peptides, and natural products like glycosides, and steroids. Catering to a diverse clientele including universities, research institutions, as well as pharmaceutical and biotechnology companies, ChemScence extends its services to include custom chemistry solutions. Furthermore, the company offers technical expertise in the domain of new drug development.
GlpBio Technology, established in 2016 and headquartered in Montclair, California, is a supplier of life science products covering 20 popular research fields, including epigenetics, neuroscience, and cancer. Its product portfolio has over 20,000 life science reagents, including biochemicals, tag peptides, bioactive peptides, amino acids, and nature products. Its main clients include clinical diagnostic laboratories, government agencies, research institutes, universities, and pharmaceutical companies. The company regularly increases its products to meet the latest research needs and provides custom organic synthesis and analytical services.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Cymetech Corporation was founded in 2000, and its headquarters is in Calvert City, Kentucky in the United States, as a producer and supplier of ultra-high purity Dicyclopentadiene (DCPD) and Methylcyclopentadiene Dimer (MCPDD). Cymetech Corporation is extensively acknowledged for its remarkable product quality and consistency, exemplary customer service, and robust supply chain security. The products provided by the company cater to a diverse range of applications and markets, encompassing electronics and electrical, transportation, fuels, automotive, defence, energy, and various other sectors.
Hangzhou Jeci Biochem Technology Co., Ltd., was established in 2002 and headquartered in Hangzhou, Zhejiang province, is a manufacturer of active pharmaceutical ingredients and intermediates. The company provides an extensive and diverse product portfolio, including anti-inflammatory drugs, Nirmatrelvir intermediates, anti-hyperlipidemia drugs, anti-tumor drugs, and anti-virus drugs. These active pharmaceutical ingredients and intermediates are integral in various applications, serving as pharmaceutical intermediates, industrial raw materials, chemical components, and essential substances for advanced intermediate production.
ALPHA CHEMICA, established in 1985, is an Indian manufacturer and supplier of laboratory reagents and fine chemicals, headquartered in Mumbai, Maharashtra. Their wide range of products includes high-performance liquid chromatography (HPLC), analytical reagent/guaranteed reagent (AR/GR), laboratory reagents (LRs), and fine chemicals, catering to life science and other specialty research. During the COVID-19 pandemic and its aftermath, ALPHA CHEMICA offered BactGO, a disinfectant solution with stabilized hydrogen peroxide using silver-based chemistry, and BaVi-X, a 75% alcohol-based hand sanitizer.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
SUVCHEM, established in 2004 and headquartered in Mumbai, India, is a manufacturer and exporter of laboratory chemicals and reagents. Their diverse product range includes organic and inorganic chemicals utilized in pharmaceuticals, plastics, water treatment, and more. They also offer biological stains and indicators for laboratory applications like cell culture and DNA analysis, along with culture media ingredients for growing microorganisms. SUVCHEM's products cater to schools, colleges, research laboratories, pharmaceutical and chemical companies, and other industries, supporting teaching, research, product development, and manufacturing processes across various sectors.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
BioCrick Co., Ltd is located in Chengdu Tianfu Life Science Park in Sichuan Province, China. The company creates a natural product library which provides small molecular compounds with potential biological and pharmacological activities for pharmaceutical, agricultural, and biotechnology companies worldwide. The company’s database includes more than 8,000 compounds collected from natural sources such as as medicinal plants, herbs, fungus, and microbes. The company also a provider of peptides and lab reagents for biological research, carrying a product line in apoptosis, epigenetic, and cancer biology.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | SUVCHEM |
16.7%
|
| 2 | MilliporeSigma |
16.7%
|
| 3 | ChemScence |
8.3%
|
| 4 | Central Drug House |
8.3%
|
| 5 | Otto Chemie Pvt. Ltd |
8.3%
|
| 6 | Hangzhou Jeci Biochem Technology Co., Ltd. |
4.2%
|
| 7 | Alpha Chemica |
4.2%
|
| 8 | MP Biomedicals |
4.2%
|
| 9 | BioCrick |
4.2%
|
| 10 | Cymetech Corporation |
4.2%
|
Derivation Method
The ranking is calculated based on the click share within the cytidine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
9 | 60.0% |
|
India
|
3 | 20.0% |
|
China
|
1 | 6.7% |
|
Japan
|
1 | 6.7% |
|
United Kingdom
|
1 | 6.7% |
