All Categories
History
This section provides an overview for adenosine as well as their applications and principles. Also, please take a look at the list of 11 adenosine manufacturers and their company rankings. Here are the top-ranked adenosine companies as of December, 2024: 1.Jigs chemical, 2.Spectrum Chemical Mfg. Corp., 3.Alpha Chemica.
Table of Contents
Adenosine is a substance produced by the breakdown of ATP (adenosine triphosphate), the main source of energy in muscle and brain cells.
It is said to be one of the sleep substances. During the day, adenosine is produced when ATP is burned and broken down by muscle and brain cells as they work.
Caffeine is also used to inhibit the action of adenosine. In general, this is often the reason why caffeine is excluded from products intended to make people sleepy.
The principal uses of adenosine are:
Adenosine is not found in actively ingested items because it is a substance produced by the body through degradation. However, recent research has discovered agonists and antagonists for the receptors of adenosine, and their pharmacological and other effects have been clarified.
Among those that have reached practical application are drugs that apply load induction to diagnose heart disease. This will allow people who are unable to exercise to diagnose heart disease through myocardial blood flow scintigraphy.
However, when used to diagnose heart disease, it is also essential to be aware of side effects. The use of adenosine for stress induction can cause chest discomfort and excessive hypotension. Therefore, it is important to be prepared to deal with any side effects that may occur, such as measuring blood pressure and checking electrocardiograms during use.
Adenosine has also been used in hair-growth agents in recent years. In addition to its hair-growth effects, it is also essential for hair-growth agents to regulate the hair cycle.
Adenosine is said to act on the papilla cells in human hair follicles to promote hair growth and regulate the hair cycle. For this reason, adenosine is used not only to diagnose heart disease but also in hair growth products.
Adenosine is also used in cosmetics. Cosmetics containing adenosine can reduce the appearance of skin blemishes and wrinkles. Melamine is said to be a typical cause of skin spots and wrinkles, and is more likely to occur when skin turnover is disrupted.
To suppress spots and wrinkles, it is essential to regulate skin turnover and increase skin metabolism. Adenosine has been shown to increase skin metabolism, which is necessary to promote turnover.
Adenosine is a nucleotide consisting of adenosine and ribose bound together. The chemical formula of adenosine is C10H13N5O4. Adenosine is white in color.
It is soluble in water, but almost insoluble in ether. Its melting point is about 235°C and boiling point is 676.3°C. At room temperature (20°C), adenosine is a solid.
Although adenosine is produced in the body of living organisms, it is possible to produce adenosine industrially by hydrolyzing nucleic acids.
For example, hydrolysis of ATP yields adenosine-5-phosphate (AMP) and pyrophosphate.
Precautions for handling and storage are as follows:
*Including some distributors, etc.
Sort by Features
Sort by Area
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Actylis is based in Port Washington, New York, USA, and is an ISO 13485-certified custom manufacturer of chemical compounds that was established in 1978 as a subsidiary of Aceto. The company mainly produces specialty chemical products for the pharmaceutical, biopharm, and agriscience sectors. These chemical products include cell culture ingredients, active pharmaceutical ingredients (APIs), and buffering salts. It also offers excipients, adenosine for cosmetic ingredients, and vitamins for nutritional supplements. The company operates internationally, with manufacturing facilities in Germany, the United Kingdom, and India. Some of its notable clients include Novartis, Nestlé, and Estée Lauder.
Chemodex Ltd., established in 2001 and based in St. Gallen, Switzerland, is a manufacturer of fine chemicals, covering different fields such as reagents for life sciences, bioactive molecules, and organic pollutants. The company offers a range of products including fluorescent substances derived from fluorophores such as coumarin, rhodamine, and pyrene. These products are typically used as probes, stains, and in other applications by life-science researchers in academia, biotechnology, and the pharmaceutical industry. Its customer base includes small and medium businesses, large enterprises, as well as academic institutions.
ALPHA CHEMICA, established in 1985, is an Indian manufacturer and supplier of laboratory reagents and fine chemicals, headquartered in Mumbai, Maharashtra. Their wide range of products includes high-performance liquid chromatography (HPLC), analytical reagent/guaranteed reagent (AR/GR), laboratory reagents (LRs), and fine chemicals, catering to life science and other specialty research. During the COVID-19 pandemic and its aftermath, ALPHA CHEMICA offered BactGO, a disinfectant solution with stabilized hydrogen peroxide using silver-based chemistry, and BaVi-X, a 75% alcohol-based hand sanitizer.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Joshi Agrochem Pharma, established in 1971 and based in Mumbai, India, is a manufacturer, supplier, and exporter of various chemicals, solvents, and metals. The company maintains a stock of agro fertilizers, pesticides, and pharmaceuticals. It has a readily available inventory of 2,000 products, including agrochemicals, solvents, and APIs. These products are utilized in a range of industries, such as automobile, aerospace, and agriculture. The company holds ISO 9001 and ISO 14001 certification and operates as part of the Joshi Group of companies, which is comprised of four companies that are segmented to ensure smooth business in varying domains.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Jigs chemical |
19.6%
|
| 2 | Spectrum Chemical Mfg. Corp. |
13.1%
|
| 3 | Alpha Chemica |
11.2%
|
| 4 | Fresenius Kabi USA, LLC. |
8.4%
|
| 5 | JOSHI AGROCHEM PHARMA PVT LTD |
8.4%
|
| 6 | MilliporeSigma |
8.4%
|
| 7 | Chemodex Ltd. |
6.5%
|
| 8 | Central Drug House |
6.5%
|
| 9 | Actylis |
6.5%
|
| 10 | Otto Chemie Pvt. Ltd |
6.5%
|
Derivation Method
The ranking is calculated based on the click share within the adenosine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
5 | 55.6% |
|
United States of America
|
3 | 33.3% |
|
Switzerland
|
1 | 11.1% |
