10 Tablet Hardness Tester Manufacturers in 2023
This section provides an overview for tablet hardness testers as well as their applications and principles. Also, please take a look at the list of 10 tablet hardness tester manufacturers and their company rankings.
What Is Tablet Hardness Testers?
Tablet Hardness Testers are tools used to measure the hardness of tablets of pharmaceuticals and other products.
Tablet hardness is correlated with the physical properties of the drug product and it is generally believed that the higher the hardness, the lower the solubility in the body. On the other hand, if the hardness is low, the tablet may be crushed during transportation, which not only impairs the stability and uniformity of the product, but also may change the composition depending on the material. Therefore, it becomes necessary to control the tablet hardness.
Other tests to confirm sufficient solubility in the body include the disintegration test. It has been said that tablets with low hardness tend to disintegrate more easily. Recently, however, a new type of tablet has been developed and marketed: orally fast-disintegrating tablets, which have high disintegrating ability despite their low hardness.
Applications of Tablet Hardness Testers
Tablet Hardness Testers are commonly used for research and development and quality control of tablets, especially for pharmaceutical products.
Pharmaceutical manufacturers need to check various output items during the design and improvement stages of pharmaceutical products. quality are checked during validation, which evaluates the adequacy of the manufacturing process on the production line.
After confirming that there are no problems at the design stage, manufacturing is started. Some manufacturers also test hardness at a set frequency as a control item. Even when there is a complaint, we sometimes measure the hardness with a tablet hardness tester for quality confirmation.
Principle of Tablet Hardness Testers
Tablet Hardness Testers are basically designed to measure the hardness of tablets by placing a tablet between two plates, applying pressure at a constant rate in one direction, and measuring the force just before the tablet is broken. The hardness value reflects either or both of the breaking strength, in which the cross section of the tablet is broken, and the crushing strength , in which the shape itself is destroyed and the structure is lost.
In addition, there are several factors that influence the results of the measurement. The pressure plate, which is the plate that clamps the tablet, must have a smooth, frictionless contact surface with the tablet and must be parallel to it. The load application rate during pressurization must also be constant. This is because unpredictable crushing may occur and sudden loads may be applied. In order to obtain reproducible results, the orientation of the tablets must also be consistent. For example, in the case of a tablet with a scored line, the scored line must be placed parallel or perpendicular to the pressure plate.
There are various types of Tablet Hardness Testers, depending on such factors as the structure of the tablet holding section and the mechanism by which the pressure plate moves. Manual tablet hardness testers with a relatively simple structure include the Monsanto type that applies pressure with a spring and screw, the Pfizer type that uses pliers as a tool, and the Strong Cobb type that applies a load using compressed air.
List of 10 Tablet Hardness Tester Manufacturers
*Including some distributors, etc.
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LABINDIA ANALYTICAL INSTRUMENTS PVT. LTD.
Tablet Hardness Tester - (TH 12 SMART)
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CCS GROUP
TABLET HARDNESS TESTER
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Fison Instruments Ltd.
Tablet Hardness Tester FM-THT-A102
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Charles Ischi AG
p5-all-parameter-testing
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Copley Scientific Limited
Tablet Hardness Testing (Breaking Force)
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Labtron Equipment Ltd.
Tablet Hardness tester LTHT-A11
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SOTAX
Tablet Hardness Testers
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ERWEKA GmbH
Tablet Hardness Testers
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Tablet Hardness Tester Manufacturer Ranking
*Including some distributors, etc.Number of Employees
Newly Established Company
- BIOEVOPEAK INC.: 2010 (13 years ago)
- Natoli Engineering Company, Inc: 1973 (50 years ago)
Company with a History
- Natoli Engineering Company, Inc: 1973 (50 years ago)
- BIOEVOPEAK INC.: 2010 (13 years ago)
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