This section provides an overview for cell sorters as well as their applications and principles. Also, please take a look at the list of 10 cell sorter manufacturers and their company rankings. Here are the top-ranked cell sorter companies as of November, 2024: 1.Cytonome/ST, LLC, 2.NanoCellect Biomedical, Inc, 3.Nebula Electronics Co., Ltd..
Table of Contents
A cell sorter is a device used to isolate specific cells. In recent years, single-cell analysis, in which biological phenomena are observed at the level of a single cell, has become increasingly important in biological research.
Flow cytometry is a representative technology for high-throughput analysis of individual cells, and a cell sorter is used to separate and collect cells. A cell sorter, like a flow cytometer, allows cells labeled with a specific marker to flow through a tube. Only a specific population of cells can be aseptically sorted into a separate tube. The separated and collected cells can then be cultured for further analysis.
Cell sorters are used in a variety of fields, including cancer research, genetics, immunology, and culture engineering. Recently, the technology has also been applied in the medical field. For example, attempts are being made to use cell sorters to extract hematopoietic stem cells alone and transplant them into patients with leukemia.
In the field of regenerative medicine, plans are underway to induce differentiation of necessary cells in vitro from pluripotent stem cells, such as ES cells and iPS cells, and to use them for transplantation therapy and drug development. In this case, too, it is important to collect only the target cells, and cell sorter technology is being used to isolate and collect specific cells.
The first step in the cell sorter process is to pass the cell suspension through a very thin tube and separate the cells one by one. At this point, the cells are designed to flow from top to bottom, and the cells fall as droplets from the tip of the nozzle. Next, the falling cells are irradiated with laser light, and the scattered light from them is analyzed to read the characteristics of each cell. The instrument instantly determines whether the cells should be separated or not. When a cell to be separated is detected, the droplet containing that cell is given a + or - charge. The charged droplet then falls between two subsequent polarizers. Droplets with a + charge are attracted to the negative plate, and droplets with a - charge are attracted to the positive plate and collected in the test tubes placed under each plate. Uncharged droplets fall vertically and are usually discarded. Some instruments use microplates as collection vessels, and cells can be aliquoted into each well of the plate.
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Beckman Coulter, Inc. is a manufacturer of scientific research instruments primarily for the academia and pharmaceutical markets. The company is a merger between Beckman Instruments, Inc. and Coulter Corporation based in Indiana, United States with a history dating back to 1935. Beckman Coulter develops and manufactures instruments for the clinical research market, and applied markets including food and beverages, agriculture, oil and gas, and aerospace. The company's range of instrument and reagents include Air and Liquid Particle Counters, Centrifuges, and Genomic Solutions.
Cytonome/ST, LLC, established in 2009 and located in Bedford, Massachusetts, USA, is a manufacturer of technologies for cell purification and platform design, serving the field of cell therapy. The company is ISO 13485 certified, and its product varieties include advanced cell sorters, microfluidic chips, and cell processing platforms. These technologies offer benefits such as precise cell sorting, enhanced therapeutic development, and improved cell therapy manufacturing processes. Its solutions find applications in various industries, primarily within the cell therapy sector, supporting the development and production of cell-based therapies for a wide range of medical conditions.
NanoCellect Biomedical, Inc, founded in 2011 in San Diego, California, USA, is a manufacturer of a benchtop microfluidic cell sorter known as the WOLF Cell Sorter. Researchers can separate particular cell populations with the use of the company's advanced device, which delivers precision cell sorting. Its robust, powerful cell sorting system, which has earned ISO 9001 certification, improves research capacities. Improved cell survival, decreased sample contamination, and greater experimental flexibility are some of the advantages. It is used for everything from stem cell biology to immunology and cancer research in the living sciences, industry, pharmaceutical research, and academic institutions.
Xiamen WinAck Battery Technology Co., Ltd, founded in 2011 in Xiamen, China, is a manufacturer of battery pack assembly lines. The company specializes in spot welding machines, battery cell sorting machines, battery pack assembly lines, battery testing equipment, and battery PCM testers. Its assembly lines are ISO 9001 certified and provide consistent performance, lower labor costs, improved product quality, and increased production efficiency. Its assembly lines are vital to the development of cleaner and more efficient energy storage systems and are used in an array of industries, such as consumer electronics, industrial power solutions, renewable energy storage, and electric cars.
Fujian Nebula Electronic Co., Ltd, founded in 2005 in Xiamen, Fujian, China,is a manufacturer of battery test and ESS (Energy Storage System) solutions. The company holds ISO 9001 and ISO 14001 certifications, and its product range encompasses battery testers, ESS test equipment, battery simulators, and cloud-based battery data management systems. These solutions offer benefits such as accurate and efficient battery testing, improved ESS performance, and comprehensive data analysis for proper decision-making. Its products find applications across various industries, including renewable energy, electric vehicles, consumer electronics, and telecommunications, resulting in the growth of clean energy technologies and efficient energy storage systems.
XIAMEN TOB NEW ENERGY TECHNOLOGY Co., LTD., established in 2012, is a manufacturer based in Xiamen, China, specializing in equipment and materials for lithium-ion batteries. The company offers lithium-ion battery and lithium-ion supercapacitor materials, production and testing equipment. Other offerings include battery mixers, battery winding, sealing, and crimping machines as well as electrode coating, slitting, and staking machines. TOB NEW ENERGY serves various industries, including electric vehicles, energy storage systems, and portable electronics. They have designed over 200 lithium-ion battery and supercapacitor production lines for companies and research institutions like Mercedes-Benz AG, Bayerische Motoren Werke (BMW) AG, Massachusetts Institute of Technology (MIT).
Maestrotech Systems Private Limited, established in 2013 in Pune, Maharastra, India, is a manufacturer of turnkey solutions for Lithium Battery Pack assembly lines. The company has achieved ISO 9001 certification for the stability and robustness of its products. Its turnkey solutions offer numerous benefits, including increased production efficiency, reduced labor costs, enhanced product quality, and full traceability of battery packs. The products find application in electric vehicles, renewable energy storage, consumer electronics, and industrial energy solutions. It offers premium technologies that result in the growth of the lithium battery industry and the adoption of clean and sustainable energy solutions.
Sony Biotechnology, Inc., founded in 1995 and headquartered in San Jose, California, US, is a manufacturer of imaging and cytometry products. Its product portfolio entails spectral cell analyzers, reagents, and cell soarters used in biomedical research, drug discovery, immunology, and cancer biology.The company's reagents and instruments are used in laboratories globally to allow scientists to sort and analyze cells. The company also provides customer service, technical support, and instrument services. It has also established partnerships with researchers by offering educational resources, training programs, and technical assistance.
Miltenyi Biotec Inc. founded in 1989 in Germany is a manufacturer, designer, developer of products for biomedical research and genetic therapy. Its products include MASC cell separation, devices for unlocking isolation power, the Clini MASC platform for automated cell production on a closed and scalable platform, MACSima platform for investigating 1 sample with 100 markers, MASC antibodies and more.The Auto Masc Neo Separator sets the standard for automated cell separation, while dead cell removal reagents guarantee the elimination of dead cells, debris, endotoxins, and myelins.Biomedical science is driving changes in the treatment of cancer, autoimmune diseases, and neurodegenerative disorders.
Xiamen Acey New Energy Technology Co., Ltd, established in 2009, based in Fujian, China, is a high-tech enterprising R&D team specializing in researching and manufacturing of high-end equipment for lithium-ion batteries. The company’s products include battery raw material, lab-scale fabrication machine for coin cell, cylindrical cell and pouch cell, battery pack assembly line and super capacitor production equipment. They have a professional team strict on quality control and provide thoughtful customer services. The company designs more than 60 lithium ion battery and supercapacitor production lines located in the United States, Russia, India, Southeast Asia, and South America, among others.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Cytonome/ST, LLC |
29.0%
|
2 | NanoCellect Biomedical, Inc |
14.5%
|
3 | Nebula Electronics Co., Ltd. |
13.0%
|
4 | Sony Biotechnology, Inc. |
11.6%
|
5 | Miltenyi Biotec Inc. |
11.6%
|
6 | Beckman Coulter, Inc. |
10.1%
|
7 | XIAMEN TOB NEW ENERGY TECHNOLOGY Co., LTD. |
4.3%
|
8 | Maestrotech Systems Private Limited |
2.9%
|
9 | Xiamen WinAck Battery Technology Co., Ltd |
1.4%
|
10 | Xiamen Acey New Energy Technology Co.,Ltd. |
1.4%
|
Derivation Method
The ranking is calculated based on the click share within the cell sorter page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
China | 4 | 57.1% |
United States of America | 3 | 42.9% |
3 products are listed.
Beckman Coulter Life Sciences
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■ Cytoflex with a sorting function ・ Excellent sensitivity suitable for multi -color applications ・ Because the parameters match the Cytoflex S V...
Beckman Coulter Life Sciences
30+ people viewing
■ optical system ・ System that can set seven lasers / seven pin holes: 355 NM, 405 nm, 488 nm, 532 nm, 560 nm, 592 nm, 645 nm ・ Single Multi-Lase...