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This section provides an overview for aniline hydrochloride as well as their applications and principles. Also, please take a look at the list of 20 aniline hydrochloride manufacturers and their company rankings.
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Aniline hydrochloride is an organic compound with the chemical formula C6H8ClN and is classified as an aromatic ammonium salt.
The CAS registration number is 142-04-1. Other names include aniline hydrochloride, benzeneamine hydrochloride, phenylamine hydrochloride, aniline chloride, aniline salt, and phenylammonium aniline chloride hydrochloride.
The name according to IUPAC nomenclature is anilinium chloride. Aniline hydrochloride is designated as a deleterious substance under the Poisonous and Deleterious Substances Control Law.
Aniline hydrochloride is mainly used as a raw material for dyes and organic synthesis. Aniline hydrochloride is known to oxidize to an insoluble black dye called aniline black, and this reaction is used to dye textiles.
In addition, the reaction of aniline hydrochloride with nitrous acid at temperatures below 5°C produces benzenediazonium chloride. This benzenediazonium chloride is a substance that causes diazo coupling when mixed with phenol salts.
The product of diazo coupling is a red-to-yellow dye, which is used for dyeing. Aniline hydrochloride is also a substance used as an intermediate in aniline synthesis.
Aniline hydrochloride has a molecular weight of 129.59, a melting point of 198°C, and a boiling point of 245°C (decomposition).
It turns dark when exposed to air and light. Its density is 1.22 g/mL and its solubility in water is 107 g/100 mL (at 20°C). It is soluble in ether and ethanol as well as water. It is insoluble in benzene.
Aniline hydrochloride is sold mainly as a reagent product for research and development and as an industrial chemical. Potential applications for industrial chemicals include raw materials for pharmaceuticals, flux, and organic synthesis.
R&D reagent products are available in 25g, 100g, 500g, and other capacities. Generally, they are provided in capacities that are easy to handle in the laboratory. They are stored at refrigerated or room temperature.
Aniline hydrochloride is obtained by adding concentrated hydrochloric acid to aniline. In the method of aniline synthesis in which nitrobenzene is reduced with tin and hydrochloric acid, the resulting aniline may react with excess hydrochloric acid to give aniline hydrochloride.
Since aniline hydrochloride is a weak base, the addition of a strong base, such as sodium hydroxide, liberates aniline. Another important chemical reaction of aniline is the synthesis of benzenediazonium chloride.
The reaction of aniline hydrochloride with nitrous acid at temperatures below 5°C gives benzenediazonium chloride. Benzene diazonium chloride reacts with phenol salts in a diazo coupling reaction to give various diazo compounds. In general, diazo compounds are useful as dyes and dyestuffs.
Aniline hydrochloride is stable under normal handling conditions, but is flammable and decomposes upon heating or contact with acids. It reacts vigorously, especially with oxidizing agents, producing toxic and corrosive fumes containing aniline, nitrogen oxides, and hydrogen chloride.
Aniline hydrochloride is classified by the GHS classification as having the following hazards
Due to these hazards, aniline hydrochloride is classified as a deleterious substance under the Poisonous and Deleterious Substances Control Law. It is important to handle it correctly in compliance with the law.
*Including some distributors, etc.
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Cayman Chemical Company is a manufacturer of life science research products founded in 1979 in Ann Arbor, Michigan, USA. They offer a diverse array of analytical standards, reagents, and other products for research in cancer, oxidative injury, epigenetics, neuroscience, inflammation, as well as metabolism, and other areas. The company supplies small molecules, biochemicals, assay kits, antibodies, and proteins to research scientists across academic, biotechnology, and pharmaceutical institutions. Cayman Chemical Company holds dual accreditations to ISO/IEC 17025:2017 and ISO 17034:2016 by ANAB Accreditation Services.
SIELC Technologies is a specialized manufacturer and developer of high-performance liquid chromatography (HPLC) columns, devices, and systems. The company was founded in 2001 and is based in Illinois, with a network of partner distributors in over 30 countries across six continents. The company's product portfolio is centered around various HPLC columns including chiral, normal- and reverse-phase, ion-exchange, and mixed-mode models. These supply clients in the biotech, pharmaceutical, petrochemical, and cannabis industries.
Krackeler Scientific, a company established In 1951 in Albany, New York, is a distributor of scientific products such as general laboratory supplies, tissue culture products, chromatography consumables, lab safety products, and sophisticated biological kits. It distributes products like animal cages and enclosures, counting devices, environmental glassware, grinders, and ice makers. The company sources the equipment from brands like the American National Can, DuPont Personal Protection, Edwards High Vacuum, Encon Safety Products, and Kendall Healthcare Products.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Manchester Organics Ltd., established in 1996 and headquartered in Cheshire, England, is a manufacturer of organic building blocks, intermediates & research chemicals. The company offers over 50,000 building blocks and fine organic chemicals. It specializes in fluorination technology and general organic synthesis at all scales and provides a chemically diverse range of custom synthesis services, development and scale-up projects. The company has multiple milligram to multi-kilo production facilities with high pressure capability and cGMP specialist fluorination facility.
SimSon Pharma Limited, established in 2011 and headquartered in Mumbai, India, is a manufacturer and supplier of pharmaceutical reference materials. Their product range includes drug working standards, drug impurity standards, drug metabolites, and stable isotope labeled compounds. These provide a basis for comparison and validation, enabling pharmaceutical companies to produce safe and effective medications. The company's offerings serve specific purposes, such as calibrating analytical instruments and ensuring precise analytical results, identifying and quantifying impurities in drugs, understanding drug metabolism, and developing new drug therapies.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
BLDpharm was founded in 2014 and headquartered in Shanghai, China is a manufacturer and supplier of various research chemicals. The company offers a wide range of laboratory chemicals including heterocycles, boron acids, amino acids, metal catalysts, and chiral compounds. These quality products find an array of applications as inhibitors for metabolic enzymes, pharmaceutical intermediates for antipsychotic drugs, catalysts for chiral resolving reagents, and material science for OLED material and synthesis intermediates.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Carl Roth GmbH + Co. KG, established in 1879 and headquartered in Karlsruhe, Germany, is a manufacturer, distributor, and supplier of laboratory equipment, life science products, and chemicals. Their extensive product range encompasses analytical instruments, biological safety cabinets, heating mantles, pH meters, centrifuges, thermometers, and various chemicals. Their products support and facilitate laboratory research, analysis, and experimentation across various industries such as pharmaceutical, chemical, and environmental sectors. The company is certified according to DIN EN ISO 9001:2015 and DIN EN ISO 14001:2015.
A.H.A. International Co., Ltd., established in 1982 and headquartered in Hefei, China, operates as a distributor and supplier offering fuels, dangerous chemicals, medical instruments, and more. The company's product range encompasses monosodium glutamate, citric acid anhydrous, sodium benzoate powder, monohydrate citric acid, amoxicillin trihydrate, and others. These products are used across diverse industries, including health & medicine, food & beverage, and the fine & specialty chemical sector. The company's products have achieved several certifications, including GMP, CEP, HACCP, Kosher, and Halal.
Yuanfar International Trade Company, established in 2001 and headquartered in Xi'an, Shaanxi, China, is a distributor of nonferrous metals, chemicals, and solar-photovoltaic products while providing professional foreign trade supply chain services. Its product range includes chemicals like Hydrazine hydrate, Mono-methyl hydrazine, DMF, Acetonitrile, and Fluorine products, serving diverse industries and exporting to countries such as Europe, the USA, India, and Japan. With two decades of experience, the company has cultivated strong partnerships with chemical companies in China, contributing to global trade.
HAZMAT Resource, Inc., located in Irvine, California, USA, is a distributor of hazardous materials response equipment and materials. They specialize in personal protective equipment (PPE), testing devices, and technical reference materials for hazardous materials (hazmat) response. Their product range includes PPE such as suits, gloves, boots, and respirators to safeguard hazmat responders from dangerous substances. They offer various testing devices like meters, detectors, and kits for precise identification and measurement of hazardous materials. Additionally, the company provides technical reference materials like books, manuals, and software, equipping responders with essential knowledge on hazardous material properties and safe handling procedures.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Carl Roth GmbH + Co. KG |
100.0%
|
Derivation Method
The ranking is calculated based on the click share within the aniline hydrochloride page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
5 | 31.3% |
|
India
|
3 | 18.8% |
|
China
|
3 | 18.8% |
|
Japan
|
1 | 6.3% |
|
United Kingdom
|
1 | 6.3% |
|
Canada
|
1 | 6.3% |
|
Germany
|
1 | 6.3% |
| Saudi Arabia | 1 | 6.3% |
