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This section provides an overview for nitrobenzene as well as their applications and principles. Also, please take a look at the list of 15 nitrobenzene manufacturers and their company rankings. Here are the top-ranked nitrobenzene companies as of December, 2024: 1.Shiv Chemicals, 2.KANTO CHEMICAL CO.,INC., 3.Redox Industries Limited.
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Graduated from Hokkaido University Graduate School in 2013, Ph.D. (Science), postdoctoral researcher, foreign-affiliated chemical company, pharmaceutical manufacturing research and development, and currently freelancer.
Specializes in organic chemistry, synthetic chemistry, and pharmaceutical process chemistry.
linkedin: www.linkedin.com/in/naoto-kinashi-61209a172
Thesis
https://doi.org/10.1016/j.tetlet.2013.06.085
https://doi.org/10.1021/acs.orglett.7b03695
https://doi.org/10.1016/j.tetlet.2015.11.079
Nitrobenzene, an aromatic nitro compound with the chemical formula C6H5NO2, is also known as nitrobenzole. It is a pale yellow liquid with an almond-like aroma, a melting point of 5.7°C, a boiling point of 210.8°C, and a specific gravity of 1.20. Soluble in organic solvents but insoluble in water, nitrobenzene is classified as a deleterious substance under various laws and regulations.
Nitrobenzene is synthesized through nitration, reacting benzene with a mixed acid of concentrated sulfuric and nitric acids. This exothermic reaction produces nitronium ions (NO2+), which react with benzene to form nitrobenzene, and are considered highly hazardous.
Nitrobenzene undergoes further nitration to form meta-dinitrobenzene and can be reduced to aniline. It participates in the Skraup quinoline synthesis, reacting with glycerin, aniline, and sulfuric acid to form quinoline.
Nitrobenzene is used as a synthetic intermediate in pharmaceuticals, agrochemicals, dyes, fragrances, and rubber production. It is a precursor to aniline, azoxybenzene, azobenzene, and hydrazobenzene, and is used as a polar solvent and mild oxidizing agent.
While not highly toxic, nitrobenzene is harmful and can cause nervous system, liver damage, and anemia upon exposure. Symptoms from prolonged occupational exposure include headache, nausea, dizziness, limb numbness, cyanosis, hypotension, splenomegaly, hepatomegaly, jaundice, and methemoglobinemia.
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Chemieorganic Chemicals, established in 1979, based in Gujarat, India, is a manufacturer of chlorobenzene, chloroanilines, and dinitrochlorobenzene. The company’s product portfolio includes chlorination, nitration, hydrogenation, and calcium chloride. The company’s capabilities include manufacturing products either based on its own end products or developed specifically for customers’ needs. It started as a partnership firm with a manufacturing facility to manufacture various isomers of chlorobenzenes at the Gujarat Industrial Development Corporation (GIDC) industrial estate. The company’s objective is to leverage talent, technologies and its years of expertise to deliver quality products and services.
Aarti Industries Limited (AIL) is a global manufacturer of speciality chemicals and pharmaceuticals based in India. They were founded in 1984 and provide services to the chemical industry's 700+ domestic clients as well as 400+ international clients. Chemical products produced by Aarti Industries are used in the production of pharmaceuticals, agrochemicals, polymers, additives, and dyes. They started out as an Indian company serving international markets and now they are a worldwide organization with manufacturing facilities in India.
Redox Industries Limited, established in 2008, based in Gujarat, India, is a manufacturer of plant growth promoters, biostimulants, flowering stimulants, insecticides, plant nutrients, and pesticides. The company’s product portfolio includes Receptone (Biostimulant), Reshot Super, RDX Bio Pesticide, Sodium Ortho Nitrophenolate, and Recure Bio Fungicide, among others. It also supplies Humic Acid, Amino Acid, Seaweed extract, and Fulvic acid. The company’s objective is to produce profitable bio-pesticides, bio fertilizers, plant growth promoters, and bio stimulants. Customer service is provided by staff who apply the proper techniques and inputs to provide satisfactory outcomes.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Agrocare, established in 2019 and located in is a manufacturer, importer, trader, supplier, distributor, and wholesaler of a range of products, including Seaweed Extract, Micronutrient Powder, and Liquid Humic Acid. The company prioritizes ethical business practices and maintains utmost transparency in all its transactions, fostering strong and healthy customer relations. The company’s success story is attributed to the leadership of CEO Ganapathy Sivarama Krishnan, whose support and guidance have propelled the company towards exponential growth in the current market.
AKSHAR GROUP, founded in 2013, and located in Mumbai, Maharashtra, India is a manufacturer, distributor, and exporter of Industrial and Agro chemicals. The company's product range encompasses detergent raw materials and chemicals, benzene & solvent chemicals, water treatment chemicals, food & beverage chemicals, and fertilizer chemicals. The company has a complete team comprising technically proficient Sales & Marketing professionals, skilled handling personnel, back office support, and in-house logistics capabilities. It maintains its own warehouses, accommodating both hazardous and non-hazardous cargo, strategically situated near the Mumbai seaport.
Shiv Chemicals was founded in 2013, and its headquarters is in Gorwa, Vadodara, Gujarat, India, as a manufacturer and supplier of various industrial chemicals like acetate, acetone, benzene, chloroform, cyclohexane, dimethylformamide, ethyl cellulose, and ethylene dichloride. Chemicals are manufactured by chemical engineers manipulating atoms and molecules through fusion processes. The execution of experimental procedures determines the quantification of each chemical constituent. As a consequence of this, Shiv Chemicals possesses the capability to deliver the appropriate chemical to any location conveniently.
RX Chemicals was founded in Mumbai, India, in 2011. RX Chemicals sells chemical-based products for many sectors including automobile, agriculture, airline, detergents, drain cleaning products, electrical gear, floor care, fuel treatment, gasses, personal care, laundry chemicals, medicine, oil spill chemicals, and accessories, as well as tools. RX Chemicals also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning. The company sells to customers both in India and customers internationally.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Par Industries, established in 2003 and situated in Gujarat, India, operates as a distributor and supplier of a diverse range of industrial acids and chemicals. The company's products range includes metanilic acid, diethyl meta amino phenol, meta uredo aniline, nitrobenzene, resist salt, as well as G salt, sodium bisulphite, beta naphthol, and more. The company extends its distribution network across prominent industries within India, providing these chemicals to numerous factories and industrial settings. These chemicals play vital roles in different sectors, including textiles, pharmaceuticals, and chemical manufacturing, in the creation of various products such as cosmetics and colorants.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Shiv Chemicals |
17.3%
|
| 2 | KANTO CHEMICAL CO.,INC. |
11.8%
|
| 3 | Chemieorganic Chemicals |
11.0%
|
| 4 | Redox Industries Limited |
11.0%
|
| 5 | Merck |
6.3%
|
| 6 | AKSHAR GROUP |
5.5%
|
| 7 | Aarti Industries Limited |
5.5%
|
| 8 | Central Drug House |
5.5%
|
| 9 | Agrocare |
4.7%
|
| 10 | RX Chemicals |
4.7%
|
Derivation Method
The ranking is calculated based on the click share within the nitrobenzene page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
8 | 66.7% |
|
Japan
|
4 | 33.3% |
