This section provides an overview for malic acids as well as their applications and principles. Also, please take a look at the list of 16 malic acid manufacturers and their company rankings. Here are the top-ranked malic acid companies as of November, 2024: 1.Bartek Ingredients Inc., 2.Junsei Chemical Co.,Ltd., 3.POLYNT.
Table of Contents
Okayama University Graduate School, Ph.D. (Agriculture). After working as a specially appointed Assistant Professor at Tokyo Medical and Dental University, a fluid researcher at the Okayama Prefectural Institute of Biological Sciences, and a special researcher (JSPS PD) at the Japan Society for the Promotion of Japan Science, he became independent as a freelancer.
Specializes in natural product chemistry, protein engineering, fermentation engineering, and instrumental analysis of chemicals (especially mass spectrometry chemistry).
Thesis: https://pubmed.ncbi.nlm.nih.gov/?term=HIROKAZU+USUKI
linkedin: https://www.linkedin.com/in/%E5%8D%9A%E4%B8%80-%E8%87%BC%E6%9C%A8-b83827228/
Malic acid, also known as hydroxy succinic acid, is an organic acid with the chemical formula C4H6O5. It possesses one asymmetric carbon atom, leading to the existence of optical isomers.
The naturally occurring form of malic acid is the L-form, commonly found in fruits like grapes and apples. Malic acid can be produced through the reduction of L-tartaric acid with hydrogen iodide or by the action of fumarase on fumaric acid.
1. Name
English name: L-malic acid
IUPAC name: (2S)-2-hydroxybutanedioic acid
2. Molecular Formula
C4H6O5
3. Molecular Weight
134.09
4. Melting Point
100°C (L-form)
5. Solvent Solubility
Easily soluble in water and alcohol.
Malic acid, known for its refreshing sour taste, is used as an acidulant in foods and beverages. It has inherent bactericidal properties, which are enhanced when combined with other organic acids. Consequently, it's being explored as a food additive with potential bactericidal effects. In the food industry, malic acid is used as a pH adjuster, emulsifier, and is most commonly utilized in its racemic form.
In the cosmetic industry, malic acid is used in toothpaste for its plaque and tartar prevention properties and as a pH adjuster in shampoos, due to its buffering properties. Low pH shampoos containing malic acid, combined with anti-inflammatory agents, have been reported to be effective for scalp care.
Malic acid's chelating properties enable it to form complexes with metal atoms, making it useful as a metal surface cleaning agent.
Malic acid is an intermediate in the citric acid cycle, being converted to oxaloacetic acid by malate dehydrogenase. It plays a crucial role in the energy metabolism of aerobic organisms.
Fruits such as apples and grapes are rich in malic acid.
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
MUBY CHEMICALS, established in 1976, is a manufacturer and supplier of chemicals and excipients used in pharmaceuticals, cosmetics & personal care, agrochemical, and textile industries. Based in Ankleshwar, Gujarat, India, the company offers Shale gas hydraulic Fracturing Chemicals such as ammonium persulfate, diverting agents, inhibitors, ATMP phosphonate, and encapsulated gel breakers. Some food analytical reagent chemicals include benzyl alcohol, calcium oxide, boric acid, carbamide peroxide, and lithium carbonate. The company is GLP-approved, Kosher Certified, "REACH" Registered, and ISO-9001 Certified.
POLYNT, in Scanzorosciate, Bergamo, in 1955 is a manufacturer of organic anhydrides and their derivatives. The company's product portfolio includes vinyl ester resins, bonding pastes, unsaturated polyester resins, malic acid, and bonding pastes. Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and healthcare. They also provide services such as production planning and raw materials supply , Production process, and quality control and logistics.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Dubi Chem was founded in 1995 and is headquartered in the United Arab Emirates. The company is a marine chemical manufacturer based in Asia, serving marine, oilfield, water treatment, automotive, and shipping industries. The company’s product list includes hundreds of chemicals and finished products, ranging from wheel cleaners to skin care pastes to oil drilling chemicals. The company provides services such as inspections and cleaning specialists who provide dedicated tank cleanings preloading and post-delivery, logistics services, and private labeling options for OEMs and other manufacturers to self-label.
Bartek Ingredients Inc. is a manufacturer of malic and food-grade fumaric acid that is headquartered in Hamilton, Canada, and was established in 1969. The company manufactures malic and food-grade fumaric acid serving mainly the industries of food and beverage, confectionery, animal nutrition, and industrial end-user and distribution markets. The company’s product lineup apart from malic and fumaric acid, includes taste modification technology, malic solution, artisan bread technology, bread preservation technology, and pectin enhancer.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
Thirumalai Chemicals Ltd was founded in 1672, and its headquarters is in Sion East, Mumbai, India, as a producer of Phthalic Anhydride, Malic Acid, Maleic Anhydride and Fumaric Acid. TCL takes superiority in manufacturing items utilized in individuals' daily lives. The company produces and promotes various goods catering to the needs of the plastics, paints, food, cosmetics, and pharmaceutical sectors. It has also established a commendable name for its excellence and reliability, attributed to its utilization of cutting-edge production facilities that guarantee punctual delivery and efficient logistics.
Foodchem was founded in 2006 in Shanghai, China. The company is ISO 9001 certified and is a producer, distributor, R&D provider, and marketer of specialty and standard food additives and ingredients to pharmaceutical, cosmetic, nutrition, and chemical industries around the world through distributors and self-managed warehouses. The company operates through four product segments: Food Ingredients, Feed Additives, Industrial Chemicals, and Active Pharmaceutical Ingredients. Certain categories include Kosher and Halal-certified products and products meeting other dietary restrictions.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Bartek Ingredients Inc. |
16.1%
|
2 | Junsei Chemical Co.,Ltd. |
12.5%
|
3 | POLYNT |
9.9%
|
4 | KANTO CHEMICAL CO.,INC. |
9.1%
|
5 | Thirumalai Chemicals Ltd. |
8.2%
|
6 | MUBY CHEMICALS |
7.2%
|
7 | Ingreland Limited |
6.3%
|
8 | Jigs chemical |
5.8%
|
9 | Fuso chemical Co., ltd. Japan |
5.3%
|
10 | DUBI CHEM MARINE INTERNATIOAL |
4.6%
|
Derivation Method
The ranking is calculated based on the click share within the malic acid page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 5 | 45.5% |
India | 3 | 27.3% |
China | 2 | 18.2% |
Italy | 1 | 9.1% |