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This section provides an overview for succinic acid as well as their applications and principles. Also, please take a look at the list of 15 succinic acid manufacturers and their company rankings. Here are the top-ranked succinic acid companies as of December, 2024: 1.RPI, Corp., 2.Vigon International, 3.Guangzhou ZIO Chemical Co..
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Okayama University Graduate School, Ph.D. (Agriculture). After working as a specially appointed Assistant Professor at Tokyo Medical and Dental University, a fluid researcher at the Okayama Prefectural Institute of Biological Sciences, and a special researcher (JSPS PD) at the Japan Society for the Promotion of Japan Science, he became independent as a freelancer.
Specializes in natural product chemistry, protein engineering, fermentation engineering, and instrumental analysis of chemicals (especially mass spectrometry chemistry).
Thesis: https://pubmed.ncbi.nlm.nih.gov/?term=HIROKAZU+USUKI
linkedin: https://www.linkedin.com/in/%E5%8D%9A%E4%B8%80-%E8%87%BC%E6%9C%A8-b83827228/
Succinic Acid is classified as a dicarboxylic acid because it has two carboxyl groups in its molecule. The name succinic acid is derived from its discovery in the dry distillation of amber.
This compound is widely used in the synthesis of various compounds, and its demand is increasing as an important raw material for the chemical industry.
Industrially, it is produced by hydrogenation of maleic anhydride, which is derived from petroleum.
Succinic acid is also produced in living organisms as a metabolite of the citric acid cycle. This has led to widespread attempts to produce petroleum-derived bio-succinic acid using bacteria and cyanobacteria.
Succinic Acid (IUPAC name: butanedioic acid) has the molecular formula C4H6O4, and molecular weight 118.09. It has a melting point of 185-187°C.
It is soluble in water and ethanol, and insoluble in diethyl ether. The taste is umami, and it is also bitter and acidic.
Succinic acid is used in a wide range of applications.
In the food industry, it is used as an umami additive, flavoring agent, and acidity regulator.
In industry and pharmaceutical manufacturing, succinic acid is used as an intermediate in the production of polymers such as polyester and polyurethane, resins, dyes, and in the synthesis of various pharmaceuticals.
Succinic acid is a well-known umami component found in shellfish such as clams. Its sodium salt, sodium succinic acid, exhibits a stronger umami taste than free carboxylic acid. It is also produced by alcoholic fermentation and is a component of the flavor of wine and beer.
Succinic acid is industrially used as a raw material for synthesizing various compounds. Polybutylene succinate, a biodegradable plastic, is a typical example of a compound synthesized from succinic acid.
Succinic acid is also used as a pH adjuster in pharmaceuticals, plating agents, and bath salts.
Succinic acid is a type of organic acid, and its mixture with conjugate base has a buffering effect and is used as a pH adjuster in cosmetics.
Succinic acid is an important intermediate in the TCA circuit and is deeply involved in the energy metabolism of many oxygen-breathing organisms; in the TCA circuit, succinic acid catalyzes succinate dehydrogenase to give fumaric acid, during which the coenzyme FAD is reduced to produce FADH2.
Succinic Acid is a dicarboxylic acid compound with two carboxylic acids in its structure. It has the molecular formula C4H6O4, molecular weight 118.09, and is designated butanedioic acid in IUPAC nomenclature.
Succinic acid is a four-carbon linear molecule with two carboxyl groups (-COOH). The two carboxyl groups make it highly acidic and soluble in water.
Succinic acid also behaves as a strong acid because the carboxyl groups release a proton.
In industrial production, succinic acid is prepared by contact hydrogenation of maleic anhydride, which is maleic acid or its dehydrated cyclide.
Succinic acid is an intermediate in the TCA circuit, so it can also be produced by fermentation using microorganisms. However, its productivity is low and it has not yet been put to practical use.
*Including some distributors, etc.
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RPI, Corp. is a manufacturer of scientific research products that was established in 1970 and is headquartered in Mount Prospect, Illinois, USA. The company’s products include antibiotics, biochemicals, buffers, growth media, laboratory supplies, and molecular biology. Its products are used by several industries, as diverse as life science research, biotechnology, and pharmaceutical. RPI, Corp. has five major product lines which as more than 7,000 items for plant and life science research laboratories. The company also offers a wide range of services, including custom antibody development, assay development, and training.
Vigon International is headquartered in East Stroudsburg, Pennsylvania, and is a subsidiary of Azelis. The company is a custom manufacturer of fragrances and flavor products used in cosmetics, food processing, and related industries. The company’s compounds originate from dozens of fruits, herbs, and spices grown in regions as diverse as California, Germany, Brazil, and Indonesia. The company’s custom processing capabilities include adding reaction flavors such as Maillard in batches from 1 to 5,000kg, vacuum distillations, essential oil folding and concentration, and emulsion production.
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
ChemCeed, founded in 2009 and headquartered in Chippewa Falls, Wisconsin, is a worldwide chemical supplier that is ISO 9001 certified. It provides chemicals like base oils, corrosion inhibitors, and specialty esters used in several industries, including construction, paper manufacturing, and water treatment. It also provides a broad selection of support services, including labeling, repackaging, and logistical support. The company stocks its products in several locations around the United States, including Chicago (IL), Philadelphia (PA, and Piscataway (NJ). In 2016, it received WBE certification and was NACD verified in 2023.
The Chemical Company (TCC) was founded in 1988 in Jamestown, Rhode Island. TCC is a distributor of chemicals, composites, and plastics. TCC strategically sources materials to provide customers with secure product supply to ensure longterm supply security. TCC’s product categories include C.A.S.E. (coatings, adhesives, sealants, and elastomers) such as adipic acid and casein, flame retardants such as dicyandiamide and calcium chloride, silanes, acid such as boric acid and citric acid, water treatment such as melatonin and nicotinamide, intermediates such as acetone, fertilizer & crop nutrition such as ammonium sulfate, and polymer additives such as resorcinol and zinc borate.
Allan Chemical Corp., established in 1984, is a distributor of specialty chemicals and raw ingredients such as Acetyl Tributyl Citrate, Ammonium Carbonate, Calcium CHrolide Dihydrate, Caffeine anhydrous powder, and ferrous ammonium sulfate used in ceramics & glass, screen printing, cosmetics & personal care, laboratory industries, food & beverage, and fragrance industries. The company in Margaret King Avenue Ringwood, New Jersey, is ISO 9001 certified, and the products conform to quality standards such as Halal, EP, ACS, FCC, and Kosher.
Wego Chemical Group was founded in 1978 and headquartered in Great Neck, New York. WEGO is a full-service supplier and distributor of chemicals, minerals, and other raw materials to clients around the world. Markets and segments include agriculture & animal care, chemical & material manufacturing, construction & building materials, electronics, food & beverage, “household, industrial & institutional”, mining, oil & gas, personal care & pharmaceutical, paper & packaging, surface treatment, textiles, and water treatment.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Guangzhou ZIO Chemical Co. is a manufacturer and supplier of specialty chemicals and food additives that was established in 2005 and is headquartered in Guangzhou, China. The company specializes in the production of food additives, cosmetic chemicals and specialty chemicals. Its products include preservatives, acidity regulators, sweeteners, antioxidants, and thickeners, as well as emulsifiers, flavors, and nutrition enhancers. Its products are used by several industries, as diverse as food, beverage, and pharmaceutical industries. The company also offers a wide range of services, including custom formulation development, and technical support.
Anhui Sunsing Chemicals Co.,Ltd., founded in 2001 in China, is a manufacturer of organic pigments and succinic acid. Dinatrium succinate belongs to the class of organic compounds and contains two carboxylic acid groups. It is a weakly acidic compound with no odor and can be found in shells, shrimp, crabs, and other seafood. Succinic acid is a colorless crystal with a sour taste and relatively high density that serves as an important raw material for pharmaceutical production. Through the fermentation process, succinic acid is used in food production and various other industrial sectors, including paper manufacturing, textiles, seasonings, plastics, and more.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nippon Shokubai Co. LTD., established in 1941 and headquartered in Osaka, Japan, is a chemical manufacturer providing diverse chemical materials. Some of its products include detergents, curing agents, heat-resistant resins, adhesives, and coatings for metal, and the products are used in various industries, including life science, ICT, consumer products, environment remediation, and energy. In 1941, the company started the first commercial production of Phthalic Anhydride, which led to the development of the vinyl chloride industry. It commercialized Ethylene Oxide in 1959 using domestic technologies and began mass-producing superabsorbent polymers in 1985.
GFS Chemicals was founded in 1928 and is based in Columbus, Ohio. GFS Chemicals is an ISO 9001:2015 certified manufacturer as well as a supplier of specialty and fine chemicals, serving customers worldwide. GFS serves an array of industries including pharmaceutical, electronics, energy, fragrances, agrichemical, and specialty polymers. GFS Chemicals supplies over 8,600 chemicals in the United States, available in both small and large quantities. GFS Chemicals also offers Karl Fischer reagents, PPT/PPB trace analysis grade acids, turbidity standards, and other high-quality materials.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | RPI, Corp. |
19.0%
|
| 2 | Vigon International |
12.0%
|
| 3 | Guangzhou ZIO Chemical Co. |
9.9%
|
| 4 | Anhui Sunsing Chemicals Co.,Ltd. |
9.2%
|
| 5 | GFS Chemicals, Inc. |
7.7%
|
| 6 | KANTO CHEMICAL CO.,INC. |
6.3%
|
| 7 | Allan Chemical Corporation |
5.6%
|
| 8 | Merck |
5.6%
|
| 9 | ChemCeed LLC |
4.9%
|
| 10 | Spectrum Chemical Mfg. Corp. |
4.2%
|
Derivation Method
The ranking is calculated based on the click share within the succinic acid page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
7 | 58.3% |
|
Japan
|
3 | 25.0% |
|
China
|
2 | 16.7% |
