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This section provides an overview for tartaric acid as well as their applications and principles. Also, please take a look at the list of 9 tartaric acid manufacturers and their company rankings. Here are the top-ranked tartaric acid companies as of December, 2024: 1.BioCrick, 2.Shilpa Chemspec International Pvt. Ltd., 3.Vinayak Enterprise.
Table of Contents
Tartaric acid, a hydroxycarboxylic acid with the formula C4H6O6, is known for its presence in many plants, especially grapes. It has a molecular weight of 150.1 and is also referred to as 2,3-dihydroxy succinic acid due to its specific structural arrangement. This acid is unique because it contains two chiral carbon atoms, leading to the existence of three isomers: L-tartaric acid, D-tartaric acid, and meso-tartaric acid, with L-tartaric acid being the most prevalent in nature.
Racemic tartaric acid, or grape acid, is a 1:1 mixture of the L- and D-forms. The melting points vary across these forms, with the L- and D-forms melting at 170°C, the meso-form at 151°C, and the racemic form at 206°C. Their CAS numbers are specific to each form, illustrating their distinct chemical identities.
As a colorless solid, tartaric acid is soluble in polar solvents, with the racemic form being an exception in water solubility. Its production primarily involves the synthesis from potassium hydrogen tartrate, a byproduct of winemaking, through various chemical processes including the addition of calcium hydroxide or calcium carbonate, followed by extraction and acidification to yield tartaric acid.
Alternative synthetic methods involve the oxidation of maleic acid or fumaric acid, though these have not seen widespread practical application.
Commonly used as a food additive, tartaric acid imparts a refreshing sour taste to soft drinks, jellies, jams, and sauces. Its salts, potassium hydrogen tartrate and sodium tartrate, serve as leavening agents that release carbon dioxide upon heating. In cosmetics, tartaric acid adjusts pH and acts as an astringent. It plays a role in organic synthesis as a naturally occurring asymmetric catalyst, notably in Sharpless oxidation for the specific synthesis of epoxides.
The term "tartaric acid" was derived from its discovery in tartar, a sediment produced in winemaking. It is found in various natural sources, predominantly in grapes, and is characterized by a slight bitterness and sharp acidity.
In 1849, Louis Pasteur's isolation and study of tartaric acid salt crystals revealed the existence of mirror-image isomers. This discovery, illustrating that these isomers rotate polarized light in opposite directions, significantly contributed to the development of stereochemistry.
*Including some distributors, etc.
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Brenntag North America, Inc., founded in 1874 with headquarters in the USA, is a subsidiary of Brenntag SE and is a distributor of chemicals and chemical products and a provider of related services to industry in the United States. The company's products include solvents, additives, catalysts, resins, dyes, and alcohols. Brenntag North America, Inc. offers services that include chemical blending solutions, chemical application development, and environmental solutions such as non-hazardous and hazardous waste disposal, transportation, and laboratory services.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Shilpa Chemspec International Pvt. Ltd, established in 1982, is a manufacturer and wholesale trader of specialty chemicals and intermediates. This private company is based in Mumbai, India, and serves local and global clients. They distribute, import, and export specialty chemicals, papers, and boards, laminates, and coated foils. Their self-adhesive labels are used in various industries, including food and beverage, health and personal care, car, motor oil, and tyre. The company has recently ventured into contract manufacturing of intermediates used in bulk drugs, dyes, agrochemicals, and metal surface treatment chemicals.
Hema Pharmaceuticals Pvt. Ltd., established in 1988 and located in Ankleshwar, Gujarat, India, is a manufacturer, exporter, and importer of pharmaceutical ingredients, active pharmaceutical ingredients (API), and API intermediates. The company’s product line includes Ursodeoxycholic Acid, Nebivolo hydrochloride, Voriconazole, and EDC HCL (Intermediate of Gliptin Series API) exported to more than 30 countries. The company has an ISO 9001:2015 quality management system, an ISO 14001:2015 environmental management system, and a GMP certificate.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Vinayak Enterprise, established in 2010 and headquartered in Gujarat, India, is a manufacturer, supplier, distributor, and exporter of food chemicals, specialty chemicals, and instant premix vending machines. The company’s product line includes film processing, oil drilling, and pharma raw materials chemicals. It has an inspecting laboratory to ensure the accuracy of composition, preciseness, self-life, and purity. The company caters to clients in India, Europe, Australia, the USA, and South Africa.
BioCrick Co., Ltd is located in Chengdu Tianfu Life Science Park in Sichuan Province, China. The company creates a natural product library which provides small molecular compounds with potential biological and pharmacological activities for pharmaceutical, agricultural, and biotechnology companies worldwide. The company’s database includes more than 8,000 compounds collected from natural sources such as as medicinal plants, herbs, fungus, and microbes. The company also a provider of peptides and lab reagents for biological research, carrying a product line in apoptosis, epigenetic, and cancer biology.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | BioCrick |
27.3%
|
| 2 | Shilpa Chemspec International Pvt. Ltd. |
20.9%
|
| 3 | Vinayak Enterprise |
13.6%
|
| 4 | Hema Pharmaceuticals Pvt. Ltd. |
9.1%
|
| 5 | Brenntag North America, Inc. |
7.3%
|
| 6 | Merck |
6.4%
|
| 7 | Kishida Chemical Co.,Ltd. |
5.5%
|
| 8 | nacalai |
5.5%
|
| 9 | KANTO CHEMICAL CO.,INC. |
4.5%
|
Derivation Method
The ranking is calculated based on the click share within the tartaric acid page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
3 | 50.0% |
|
India
|
2 | 33.3% |
|
United States of America
|
1 | 16.7% |
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L-tape acid Organic acids (hydrapic acid, citric acid, sodium citrate, glucon acid, Sodium gluconate (sodium gluconate), gluconodertalacton, Tallic...
