4 Uridine Manufacturers in 2024
This section provides an overview for uridine as well as their applications and principles. Also, please take a look at the list of 4 uridine manufacturers and their company rankings. Here are the top-ranked uridine companies as of April, 2024: 1.KANTO CHEMICAL CO.,INC., 2.MilliporeSigma.
Table of Contents
What Is Uridine?
Uridine is a substance having the structure of uracil attached to the ribose ring.
It is a nucleotide and a component of ribonucleic acid (RNA). It is widely found in the biological world in the form of nucleotides. Uridine is administered as a drug to patients with orotic aciduria, while its derivatives are used as raw materials for umami seasonings.
Uses of Uridine
Uridine was used in the development of an RNA vaccine against the novel coronavirus; once in the body, the RNA vaccine acts as RNA inside cells to stimulate acquired immunity.
The RNA that makes up the RNA vaccine is composed of pseudouridine, which replaces the uridine portion of the RNA that occurs naturally in the human body. Pseudouridine is an isomer of uridine.
Approved RNA vaccines include those developed by Moderna and those developed jointly by Biontec and Pfizer.
Properties of Uridine
Uridine is a colorless, long-needled crystal with a melting point of 165°C. It is soluble in water, pyridine, and DMSO.
The absorption maximum wavelength is 262 nm at pH 2. It is not easily hydrolyzed by dilute acids. However, it is hydrolyzed to uracil and furfural by concentrated acids.
Structure of Uridine
Uridine has the structure of a β-N1-glycosidic bond of uracil, one of the bases of DNA, to ribose. The chemical formula is C9H12N2O6 and the molar mass is 244.203.
Uridine has a pyrimidine skeleton. Therefore, it can be synthesized based on pyrimidine. For example, it can be synthesized from 2,6-diethoxypyrimidine and acetobromoribofuranose. It can also be obtained by hydrolysis of ribonucleic acid or enzymatic treatment of uridilic acid.
Other Information on Uridine
1. Physiological Effects of Uridine
It has been reported that the simultaneous administration of ω3 fatty acids with uridine has antidepressant effects in rats. It has also been reported that the simultaneous administration of uridine, ω3 fatty acids, and choline activates synapses and increases protein and phospholipid levels in the rat.
2. Structure of Uridine
Uridine is composed of ribose and uracil. Ribose is a type of monosaccharide. D-ribose is an aldose with a carbon chain length of 5, and its counterpart ketose is ribulose.
3. Compounds Containing Uridine
Compounds containing uridine are known as uridine diphosphate galactose and uridine 5'-diphosphoglucose. These compounds function as coenzymes in the biosynthesis of polysaccharides and glycosides.
4. Related Compounds of Uridine
Deoxyuridine is a compound in which uracil is attached to the deoxyribose ring. It is similar to the chemical structure of uridine, but deoxyuridine does not have a 2'-hydroxy group.
List of 4 Uridine Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- India
- Japan
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KANTO CHEMICAL CO.,INC.
Uridine
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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MilliporeSigma
Uridine
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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SUVCHEM
Uridine
Manufacturer Overview
SUVCHEM, established in 2004 and headquartered in Mumbai, India, is a manufacturer and exporter of laboratory chemicals and reagents. Their diverse product range includes organic and inorganic chemicals utilized in pharmaceuticals, plastics, water treatment, and more. They also offer biological stains and indicators for laboratory applications like cell culture and DNA analysis, along with culture media ingredients for growing microorganisms. SUVCHEM's products cater to schools, colleges, research laboratories, pharmaceutical and chemical companies, and other industries, supporting teaching, research, product development, and manufacturing processes across various sectors.
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Central Drug House
Uridine
Company Overview
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
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Uridine Manufacturer Ranking
*Including some distributors, etc.Ranking as of April 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | KANTO CHEMICAL CO.,INC. |
50.0%
|
| 2 | Central Drug House |
25.0%
|
| 3 | MilliporeSigma |
25.0%
|
Derivation Method
The ranking is calculated based on the click share within the uridine page as of April 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
Newly Established Company
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
Company with a History
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
Global Distribution of Uridine Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
Japan
|
1 | 50.0% |
India
|
1 | 50.0% |
