8 Adrenaline Manufacturers in 2024
This section provides an overview for adrenaline as well as their applications and principles. Also, please take a look at the list of 8 adrenaline manufacturers and their company rankings. Here are the top-ranked adrenaline companies as of April, 2024: 1.MilliporeSigma, 2.AdvaCare Pharma USA.
Table of Contents
What Is Adrenaline?
Adrenaline, also known as epinephrine, is a catecholamine with the molecular formula C9H13NO3. It is a hormone secreted by the adrenal glands and a neurotransmitter in the nervous system. Adrenaline is the term used in American English, while epinephrine is often used in medical contexts and the European Pharmacopoeia. It is a white to brown powdery solid at room temperature, turning brown when exposed to air and light. It is soluble in diluted hydrochloric acid but extremely insoluble in water and organic solvents like ethanol, diethyl ether, and chloroform. Adrenaline is a chiral compound, typically referring to the R (-) form.
Adrenaline is secreted in response to stress or excitement in living organisms.
Uses of Adrenaline
Adrenaline is used clinically for the treatment of anaphylactic reactions, bronchospasm in asthma and whooping cough, acute hypotension or shock, cardiac arrest, prolonging the action of local anesthetics, preventing and treating local bleeding during surgery, and dental treatments. It is also a research reagent in synthetic organic chemistry and biochemistry.
Properties of Adrenaline
1. Adrenaline Synthesis
Adrenaline is synthesized biosynthetically from L-tyrosine, progressing through L-dopa, dopamine, noradrenaline, and finally to adrenaline.
2. Physiological Effects of Adrenaline
Adrenaline stimulates sympathetic alpha and beta-adrenergic receptors, affecting heart rate, blood vessel constriction, and bronchial relaxation. It should not be used with alpha-blocking drugs like butyrophenones, phenothiazines, iminodibenzyls, zotepine, serotonin and dopamine antagonists, and dopamine receptor partial agonists due to potential adverse reactions.
Types of Adrenaline
Adrenaline products include clinical injectables and inhalants for treating asthma and other conditions, and research reagents. Available in various doses and concentrations, typical products are Epista, Bosmin, and EpiPen, which require a prescription. For R&D, adrenaline is available in various capacities like 1 g, 5 g, and 10 g, usually as R-body compounds or hydrochloride salts, requiring refrigerated storage.
List of 8 Adrenaline Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- India
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AdvaCare Pharma USA
Adrenaline
Manufacturer Overview
AdvaCare Pharma USA LLC, founded in 2014, is an American pharmaceutical manufacturer and supplier based in Cheyenne, Wyoming. The company specializes in a wide range of products, including over-the-counter (OTC) medicines, supplements, antimalarial tablets, injections, and oral suspensions. They also offer oncology tablets, injections, and powder for injections, as well as veterinary products and medical devices like injection instruments, diagnostic detection instruments, and skin and wound care products. AdvaCare's products are available under various brands, such as AmoxiCare™ for amoxicillin capsules and AdvaLife™ for supplements.
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Pace Biotech
Adrenaline
Manufacturer Overview
Pace Biotech, established in 2010 and headquartered in Himachal Pradesh, India, is a pharmaceutical manufacturer specializing in pharmaceutical injections, ear drops, and eye drops. The company's product portfolio includes a range of offerings such as dry injections, dry powder non-beta lactum block, hormonal injections, ophthalmic drops, and various other ophthalmic products. The company serves various segments of the life science industry, including biotech, clinical research, and pharmaceutical sectors. It is one of the WHO GMP injection manufacturers in India.
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MilliporeSigma
−-Epinephrine
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Pharma Cure Laboratories
Adrenaline
Company Overview
Pharma Cure Laboratories, established in 1987 and headquartered in Jalandhar, India, operates as a manufacturer and supplier of pharmaceutical and veterinary products, including injections, tinctures, and anabolic steroids. The company's product portfolio includes a range of offerings, such as sodium bicarbonate injection, tranexamic acid injection, hyoscine butylbromide injection, folic acid and niacinamide injection, vitamin B12 injection, and more. The company serves various sectors in the life science industry, including biotech, clinical research, and pharmaceutical enterprises.
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Wellona Pharma
Adrenaline
Company Overview
Wellona Pharma, founded in 2016 and headquartered in Surat, Gujarat, India, is a manufacturer and a distributor of pharmaceutical finished formulations. Its extensive product line comprises tablets, capsules, injections, creams, and ointments, offering diverse medication delivery methods. Wellona Pharma caters to an array of therapeutic areas, spanning antibiotics, antivirals, antifungals, vitamins, and more. The company operates state-of-the-art manufacturing facilities with accreditations such as WHO-GMP and ISO 9001:2015. These facilities are equipped with advanced, ultramodern technology.
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Central Drug House
Adrenaline
Company Overview
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
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Adrenaline Manufacturer Ranking
*Including some distributors, etc.Ranking as of April 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | MilliporeSigma |
62.5%
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| 2 | AdvaCare Pharma USA |
37.5%
|
Derivation Method
The ranking is calculated based on the click share within the adrenaline page as of April 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- Pharma Cure Laboratories: 60
Newly Established Company
- Pharma Cure Laboratories: 1987 (37 years ago)
Company with a History
- Pharma Cure Laboratories: 1987 (37 years ago)
Adrenaline Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Adrenaline Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
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India
|
6 | 85.7% |
United States of America
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1 | 14.3% |
