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This section provides an overview for l-tyrosine as well as their applications and principles. Also, please take a look at the list of 7 l-tyrosine manufacturers and their company rankings. Here are the top-ranked l-tyrosine companies as of December, 2024: 1.NutraCap Labs, 2.SUVIDHINATH LABORATORIES, 3.NATIONAL ANALYTICAL CORPORATION.
Table of Contents
L-tyrosine is an aromatic amino acid found mainly in dairy products and legumes.
L-tyrosine is a non-essential amino acid and is synthesized in the body from the essential amino acid phenylalanine by the action of enzymes in liver cells. It is a raw material for neurotransmitters (dopamine, adrenaline, noradrenaline, etc.) and melanin. In the thyroid gland, thyroxine, one of the thyroid hormones, is synthesized from L-tyrosine and iodine.
L-tyrosine is used in food applications (food additives, supplements, etc.) and medical applications.
L-tyrosine is seldom deficient in the body since it is synthesized by the body and is available through food sources. Under these circumstances, the neurotransmitter made from L-tyrosine is deficient, necessitating the need to supplement L-tyrosine externally.
By actively taking L-tyrosine supplements or consuming L-tyrosine-rich foods, the neurotransmitter can be replenished, maintaining normal brain function. In medical use, this amino acid is used as a component of infusions administered to patients undergoing surgery.
L-tyrosine's molecular formula is C9H11NO3 and its molecular weight is 181.19. It is a shiny needle-like crystal that is insoluble in water. It also contains a benzene ring, which can be detected by the "xanthoprotein reaction," a protein coloration reaction. L-tyrosine has optical isomers (L-L-tyrosine and D-L-tyrosine) with CAS numbers 60-18-4 (L-L-tyrosine) and 556-02-5 (D-L-tyrosine).
Of the optical isomers of L-tyrosine, the L-L-tyrosine is found in most living organisms. L-L-tyrosine is also used in food additives and pharmaceuticals.
L-L-tyrosine is produced by various manufacturers and sold in milligram to kilogram volumes. The D-body of the amino acid is distributed in very few organisms, and D-L-tyrosine is an amino acid produced by the bacterium Bacillus subtilis.
This reaction detects amino acids containing benzene rings (L-tyrosine, phenylalanine, tryptophan, etc.). Concentrated nitric acid is added to an aqueous solution of amino acids containing benzene rings, and the solution turns yellow when boiled. The solution is then cooled, and when ammonia water is added, the color of the solution changes to orange-yellow.
Phenylketonuria
L-tyrosine is a substance produced by the hydroxylation of phenylalanine by the enzyme phenylalanine hydroxylase. A congenital abnormality in phenylalanine hydroxylase results in a disease called phenylketonuria. In phenylketonuria, phenylalanine is not easily metabolized, resulting in L-tyrosine deficiency.
Leukoderma
L-tyrosine is the raw material for melanin. When melanin is produced, the benzene ring of L-tyrosine is hydroxylated by the enzyme tyrosinase to produce a substance called L-dopa. Mutations in the tyrosinase gene result in leukoderma. Leukoderma causes the skin and hair to become whitish because melanin is not produced as easily.
Cancer
L-tyrosine in proteins is phosphorylated by the enzyme L-tyrosine kinase, which converts the hydroxy group to a phosphate ester. L-tyrosine kinase is a substance that stimulates cell growth. If L-tyrosine kinase is constantly activated for some reason, cells increase abnormally and cancer develops.
L-tyrosine is believed to be effective in preventing gray hair because it is involved in the production of melanin. However, excessive intake may increase skin blemishes due to melanin production.
*Including some distributors, etc.
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NutraCap Labs was founded in 2016 and headquartered in Atlanta, Georgia, as a manufacturer and distributor of wellness and fitness supplements. The company specialises in manufacturing Nutraceuticals/Dietary Supplements which consist of encapsulation manufacturing, sports nutrition, raw health powders and product formulations. The company offers clients contract Manufacturing, custom formulation, private labelling, brand design and distribution to help them build their brand. NutraCap Labs is a fully certified GMP compliant and FDA registered company that has a sister company, Active Wholesale USA, through which they market and sell supplements to retail stores worldwide.
Suvidhinath Laboratories was founded in 1985 and is headquartered in Gujarat, India. The company is an ISO 9001-2008 certified exporter, manufacturer, trader, and supplier of laboratory chemicals and reagents to global customers, especially across South East Asia and the Gulf countries. The company’s client list includes Cadila Pharmaceuticals Limited, Gujarat State Fertilizers & Chemicals LTD, Deepak Nitrite Limited, and Indian OIl. The company’s product categories include food-grade chemicals, pharmaceutical chemicals, laboratory chemicals, and industrial chemicals.
Hefei Home Sunshine Pharmaceutical Technology Co., Ltd, established in 2013 and headquartered in Hefei City, China, is a manufacturer specializing in both standard and custom chemical synthesis. With manufacturing facilities in Anhui, Jiangsu, Zhejiang, and Inner Mongolia, Home Sunshine Pharma offers a range of products, including active pharmaceutical ingredients (APIs), intermediates, fine chemicals, coenzymes, and nucleotides. As an ISO 9001:2015 certified company, Home Sunshine Pharma serves research institutions, universities, and industries in Europe, America, and Southeast Asia with their chemical products.
Fengchen Group Co., LTD is based in Qingdao, China. The company is a manufacturer and supplier of speciality chemicals for several industries around the world including natural resources, hydrogeology, drilling, geophysics, and environmental & geotechnical services. The company’s chemical product categories include APIs, amino acids, micronutrients, package materials, and enzymes. The company also offers services including specialized transportation, samples of compounds, shipping documents needed for pharmaceutical products, and international customs support.
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | NutraCap Labs |
27.8%
|
| 2 | SUVIDHINATH LABORATORIES |
25.0%
|
| 3 | NATIONAL ANALYTICAL CORPORATION |
19.4%
|
| 4 | The Group |
11.1%
|
| 5 | Shree Sai Life Sciences |
8.3%
|
| 6 | Hefei Home Sunshine Pharmaceutical Technology Co., Ltd. |
8.3%
|
Derivation Method
The ranking is calculated based on the click share within the l-tyrosine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
2 | 50.0% |
|
United States of America
|
1 | 25.0% |
|
China
|
1 | 25.0% |
