This section provides an overview for gastight syringes as well as their applications and principles. Also, please take a look at the list of 3 gastight syringe manufacturers and their company rankings.
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A gastight syringe is a hermetically sealed syringe that can handle not only liquids but also gases.
The basic structure of the syringe is the same as that of a general glass syringe for micro-dosing (microsyringe), but the PTFE tip on the plunger tip improves the airtightness of the syringe. Gas-tight syringes are usually sold as a set consisting of a syringe (outer cylinder) part and a plunger part.
Most products have the syringe part made of glass, but the plunger part is available in various materials such as glass, metal, and resin lining, depending on the capacity and application. It is necessary to select an appropriate material according to the condition of the sample to be used.
Gastight syringes are widely used for general sample handling in laboratories as well as for quantitative weighing in analysis.
They can handle sample solutions in automatic dilution systems, automated pipetting systems, and manual samplers/autosamplers such as HPLC. The ability to handle gases is also used to handle samples in gas analysis such as GCMS, and for soil gas testing..
The gastight syringes are the same as a normal micro syringe in that it consists of an outer cylinder, a plunger, and a needle.
PTFE (tetrafluoroethylene) is a fluoropolymer and has excellent heat resistance, abrasion resistance, corrosion resistance, and sliding properties.
Precautions for handling include the following:
These are because the gastight syringes are equivalent to glassware for metering.
The types of gastight syringes can be classified in terms of capacity, shape, etc.
Gastight syringes are generally small in volume (a few µL to a few hundred µL), similar to those of ordinary micro syringes, but some of the larger syringes have a maximum volume of up to 100 mL. Exact volume can be measured and injected.
Gastight syringes are available in two types: the fixed-needle type, in which the needle is fixed to the syringe, and the interchangeable-needle type. The fixed needle type is inexpensive and versatile. On the other hand, the replaceable needle type is suitable for sampling samples with a lot of contamination or where salts, etc. tend to precipitate. In addition, needles with different shapes (needle outer diameter/length, needle tip shape) can be used depending on the application.
Interchangeable needles are further classified into the following two types:
Some gastight syringes can be disassembled and autoclaved. This is ideal for handling biological samples in biochemistry and other fields. When autoclaving, it is generally recommended to set the temperature to 110°C for about 20 minutes.
Some manufacturers sell syringes for autosamplers/instruments separately from manual syringes.
As mentioned above, gastight syringes have PTFE tip attached to the plunger, but there are also products in which the entire plunger is coated with PTFE in addition to the PTFE tip. Such products can be used for corrosive samples. Replacement plungers are also available for various products.
*Including some distributors, etc.
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Hamilton Company is a US-based manufacturer of automation and laboratory equipment including process sensors, precision measuring devices, automated liquid handling workstations, and sample management systems. Hamilton's automation solutions include flexible automated liquid handling platforms and pre-configured Assay Ready workstations that are designed for specialized methods. They also offer small liquid handling devices for temperature control, plate sealing to protect microplate-based samples during critical stop points, and barcode reading. The company is also a supplier of laboratory products such as syringes and needles.
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