All Categories

History

  1. Metoree
  2. Bio
  3. Incubator Apparatuses
  4. High Productivity Harvest (HPH) (Repligen Japan LLC)
High Productivity Harvest (HPH)-High Productivity Harvest (HPH)
High Productivity Harvest (HPH)-Repligen Japan LLC

High Productivity Harvest (HPH)
Repligen Japan LLC

About This Product

■Achieve high productivity

High Productivity Harvest (HPH) is a new application developed by Repligen. Fed-batch bioreactors can be harvested in completely sterile conditions for processing in collection columns. It also eliminates both centrifugation and depth filtration.

■Improvement of productivity

Increased throughput by taking the same number of days to collect the same titer

■Process improvement

・Suppress process-related impurities to achieve healthier culture ・Reduced number of unit operations and raw materials ・Collection of materials that can be immediately processed downstream

■Improvement of VCD and survival rate by HPH

・Compared to fed-batch, HPH fed-batch achieves 4 times the viable cell density ・Survival rate maintained close to 100%

■Improvement of product titer with HPH

・Twice the productivity compared to conventional fed-batch ・Collection in the same number of days (or less) as fed batch

■Mechanism

It consists of three main steps: starting the fed-batch process, installing the cell retention device for High Productivity Harvest, and drawing down the bioreactor. HPH start dates are flexible and vary by process. Harvesting can be completed in the same time frame as traditional fed-batch, or bioreactor runs can be extended to further increase yields depending on process and equipment constraints. ・Step A: Start the process Start the fed batch process as usual. ・Step B: CRD attachment and High Productivity Harvest Once peak cell density is achieved, attach the cell retention device (CRD) and pump in fresh medium at a low flow rate. Product collection begins slowly as fresh medium begins to be injected. ・Step C: Drawdown On the final day of the run, finish adding fresh medium and begin drawing down the bioreactor capacity. ・Step D: End of process HPH fed-batch can be completed in the same time frame as traditional fed-batch or can extend production time to further increase yields.

  • Product

    High Productivity Harvest (HPH)

Share this product


30+ people viewing

Free
Get started with our free quotation service - no cost, no obligation.

No Phone Required
We respect your privacy. You can receive quotes without sharing your phone number.

1 Models of High Productivity Harvest (HPH)

Image Part Number Price (excluding tax)
High Productivity Harvest (HPH)-Part Number-High Productivity Harvest (HPH)

High Productivity Harvest (HPH)

Available upon quote

Customers who viewed this product also viewed

Reviews shown here are reviews of companies.

Gas pressure cell stimulation device-Strex

Gas pressure cell stimulation device

Strex

480+ people viewing

Last viewed: 1 hour ago

Response time: 0.85 hours

Incubator Apparatuses

2 models listed

Cultural cell extension system Automatic extension device ST-1400 (10 cc) / ST-1440 (4 CC)-Strex

Cultural cell extension system Automatic extension device ST-1400 (10 cc) / ST-1440 (4 CC)

Strex

300+ people viewing

Last viewed: 2 minutes ago

Response time: 0.85 hours

Incubator Apparatuses

4 models listed

Fresh Nanno (refrigerated raw Nanno)-Eibis Algae Industry Research Institute Co., Ltd.

Fresh Nanno (refrigerated raw Nanno)

Eibis Algae Industry Research Institute Co., Ltd.

50+ people viewing

Last viewed: 18 minutes ago

Response time: 0.19 hours

Incubator Apparatuses

3 models listed

Large incubator Forma Stericycle CO2 incubator-

Large incubator Forma Stericycle CO2 incubator

20+ people viewing

Last viewed: 7 hours ago

Incubator Apparatuses

3 models listed

Cell extension system automatic extension device & electric stimulus model ST-1410-Strex

Cell extension system automatic extension device & electric stimulus model ST-1410

Strex

210+ people viewing

Last viewed: 1 hour ago

Response time: 0.85 hours

Incubator Apparatuses

2 models listed

Large incubator Forma Stericycle CO2 incubator CR CTS series-

Large incubator Forma Stericycle CO2 incubator CR CTS series

10+ people viewing

Last viewed: 7 hours ago

Incubator Apparatuses

3 models listed

Simultaneous extension device for microscope (for microscopic regions) ST-1500-Strex

Simultaneous extension device for microscope (for microscopic regions) ST-1500

Strex

290+ people viewing

Last viewed: 11 hours ago

Response time: 0.85 hours

Incubator Apparatuses

3 models listed

Large incubator HERAcell CO2 incubator-

Large incubator HERAcell CO2 incubator

20+ people viewing

Last viewed: 3 hours ago

Incubator Apparatuses

3 models listed

Next-generation mass culture device AchieVa-CS-Full Stem

Next-generation mass culture device AchieVa-CS

Full Stem

370+ people viewing

Last viewed: 23 hours ago

Incubator Apparatuses
Visualize cell culture Hypoxia incubator SH-140A-Blast Co., Ltd.

Visualize cell culture Hypoxia incubator SH-140A

Blast Co., Ltd.

$15,600.00

30+ people viewing

Last viewed: 5 hours ago

Incubator Apparatuses

2 models listed

XY extension device for microscope ST-1900-Strex

XY extension device for microscope ST-1900

Strex

200+ people viewing

Last viewed: 1 hour ago

Response time: 0.85 hours

Incubator Apparatuses

2 models listed

N-1 Perfusion-Repligen Japan LLC

N-1 Perfusion

Repligen Japan LLC

40+ people viewing

Last viewed: 1 hour ago

Incubator Apparatuses

2 models listed

See More Incubator Apparatuses Products

Other products of Repligen Japan LLC

Reviews shown here are reviews of companies.

N-1 Perfusion-Repligen Japan LLC

N-1 Perfusion

Repligen Japan LLC

40+ people viewing

Last viewed: 1 hour ago

Incubator Apparatuses

2 models listed

KrosFlo® FS TFF Systems KrosFlo® FS-15-Repligen Japan LLC

KrosFlo® FS TFF Systems KrosFlo® FS-15

Repligen Japan LLC

30+ people viewing

Filtration Equipment
KrosFlo® FS TFF Systems KrosFlo® FS-500-Repligen Japan LLC

KrosFlo® FS TFF Systems KrosFlo® FS-500

Repligen Japan LLC

40+ people viewing

Filtration Equipment
KrosFlo® KMPi TFF System KrosFlo® KR2i-Repligen Japan LLC

KrosFlo® KMPi TFF System KrosFlo® KR2i

Repligen Japan LLC

40+ people viewing

Filtration Equipment
KrosFlo® KMPi TFF System KrosFlo® KMPi-Repligen Japan LLC

KrosFlo® KMPi TFF System KrosFlo® KMPi

Repligen Japan LLC

50+ people viewing

Filtration Equipment
KrosFlo® KMPi TFF System KrosFlo® KTF-Repligen Japan LLC

KrosFlo® KMPi TFF System KrosFlo® KTF

Repligen Japan LLC

30+ people viewing

Last viewed: 12 hours ago

Filtration Equipment
Hollow fiber filter-Repligen Japan LLC

Hollow fiber filter

Repligen Japan LLC

30+ people viewing

Last viewed: 20 hours ago

Membrane Filters

2 models listed

TangenX® Flat Sheet Cassette TangenX® SIUS® Gamma TFF Devices-Repligen Japan LLC

TangenX® Flat Sheet Cassette TangenX® SIUS® Gamma TFF Devices

Repligen Japan LLC

50+ people viewing

Last viewed: 12 hours ago

TangenX® Flat Sheet Cassettes TangenX® PRO Cassettes-Repligen Japan LLC

TangenX® Flat Sheet Cassettes TangenX® PRO Cassettes

Repligen Japan LLC

20+ people viewing

Filtration Equipment
Fluid Management KrosFlo® KR2i RPM™ System-Repligen Japan LLC

Fluid Management KrosFlo® KR2i RPM™ System

Repligen Japan LLC

30+ people viewing

Densitometers
SpectraPor® tube closure with weight-Repligen Japan LLC

SpectraPor® tube closure with weight

Repligen Japan LLC

40+ people viewing

Last viewed: 20 hours ago

LONG® EGF Cell Culture Supplement-Repligen Japan LLC

LONG® EGF Cell Culture Supplement

Repligen Japan LLC

30+ people viewing


View more products of Repligen Japan LLC

About Company Handling This Product

Repligen Japan LLC

  • Japan

Related search keywords

Incubator Apparatuses
Incubator Apparatuses　Repligen Japan LLC
Repligen Japan LLC

This is the version of our website addressed to speakers of English in the United States. If you are a resident of another country, please select the appropriate version of Metoree for your country in the drop-down menu.

Copyright © 2024 Metoree