This section provides an overview for cycloheptanes as well as their applications and principles. Also, please take a look at the list of 7 cycloheptane manufacturers and their company rankings. Here are the top-ranked cycloheptane companies as of November, 2024: 1.Merck.
Table of Contents
Cycloheptane is a cycloalkane (alicyclic organic compound) with the chemical formula C7H14.
It has a seven-membered ring structure. It is also known as heptamethylene, and its CAS number is 291-64-5. It has a molecular weight of 98.2, a melting point of -12°C, and a boiling point of 118°C. It is a colorless, oily liquid at room temperature.
The odor is described as mildly aromatic. It has a density of 0.8110 g/cm3 and is often used as a non-polar solvent. It is readily soluble in ethanol and diethyl ether, and soluble in benzene and chloroform. It is insoluble in water.
Cycloheptane is mainly used as a laboratory chemical for organic chemical analysis and as a raw material for organic synthesis. Due to its structural characteristics as a seven-membered cycloalkane without functional group substitutions, it is used as a nonpolar solvent or as a building block.
In the chemical industry, it is used as a nonpolar solvent and as a synthetic intermediate in the manufacture of chemicals and pharmaceuticals.
Cycloheptane is a seven-membered ring, but it does not have a planar structure, so it has a three-dimensional structure with several conformations. There are two stable conformations: twisted chair and twisted boat, with the twisted chair being the most stable.
The other conformations are chair, boat, and T3, which take on these structures in the transition state between stable conformations. The ring contraction reaction under the action of aluminum chloride leads to isomerization and the formation of methylcyclohexane.
It has a low flash point of 6°C and is highly flammable. Exposure to heat or flame poses a high risk of fire. It is highly reactive with oxygen-rich substances, such as strong oxidizers, and must be avoided in storage.
Cycloheptane is generally sold as a reagent product for research and development. It is available in 1g, 5g, 25g, 25mL, etc., and is supplied in small and compact volumes that are easy to handle in the laboratory. It is handled as a reagent product that can be stored and transported at room temperature.
Cycloheptane is highly flammable, combustible, and toxic to the human body.
Methods for synthesizing cycloheptane include the reduction of the carbonyl group by clemencene reduction of cycloheptanone and cyclization using 1,6-dibromohexane and malonic acid diesters.
Cycloheptane is highly flammable, combustible, and highly hazardous. It is also toxic to the human body, causing drowsiness and dizziness. The vapors can cause eye irritation, and inhalation of large quantities may cause reduced ventilation.
When handling, it is important to keep the material away from ignition sources, such as heat, sparks, open flames, and hot objects, and to provide ventilation when in use. It is also necessary to use appropriate protective equipment, avoid inhalation of mists, vapors, and sprays, and avoid direct contact.
If contact with the human body occurs, the liquid should be removed promptly by removing clothing or running water. If inhaled, medical attention is required. In addition, when disposing of the product, it is required to outsource the work to a specialized waste disposal company licensed by the prefectural governor and dispose of the product appropriately.
*Including some distributors, etc.
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Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Vizag Chemical International was founded in Andhra Pradesh, India, in 2011. Vizag Chemical International sells chemical-based products for many sectors including automotive, agriculture, airline, deodorizers, construction chemicals, boat maintenance, degreasers, detergents, drain clean products, greases, personal hygiene, lab chemicals and equipment, fuel treatment, metal treatment, tank cleaners, swimming pool and spa chemicals, scale removers, sewage chemical treatment, as well as raw chemicals. Vizag Chemical International also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
SLS Scientific Laboratory Supplies Limited, founded in 1991 and headquartered in Dublin, Ireland, operates as a distributor of laboratory products and services. Its extensive product range includes chemicals for experiments, consumables like pipettes and gloves, diverse laboratory equipment for tasks such as measuring and mixing, as well as essential furniture pieces like cabinets and benches. Furthermore, the company provides supplementary services, including calibration, repair, maintenance, and training, to facilitate laboratory operations. The company also holds several certifications, such as ISO 9001 / ISO 14001 and REGO certification.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Merck |
100.0%
|
Derivation Method
The ranking is calculated based on the click share within the cycloheptane page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 3 | 60.0% |
United States of America | 1 | 20.0% |
United Kingdom | 1 | 20.0% |