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This section provides an overview for ethylamine as well as their applications and principles. Also, please take a look at the list of 14 ethylamine manufacturers and their company rankings. Here are the top-ranked ethylamine companies as of December, 2024: 1.Otto Chemie Pvt. Ltd, 2.Guangzhou TOSUN Pharmaceutical Co., Ltd, 3.Biosynth.
Table of Contents
Ethylamine, also known as monoethylamine, is an organic compound with the chemical formula C2H7N. It is a colorless gas at room temperature but can be liquified under certain conditions and has a peculiar odor similar to ammonia. Its molar mass is 45.08 g/mol, and it has a melting point of -80°C and a boiling point of 16.6°C, both under standard atmospheric pressure. The CAS number for ethylamine is 75-04-7.
Ethylamine is used as a raw material in various industries for producing pharmaceuticals, dyes, surfactants, and paints, often in an aqueous solution form.
In organic synthesis, ethylamine serves as a primary amine in the Birch reduction process, which is used to reduce unsaturated compounds like naphthalene and various alkyne compounds. The reaction involves dissolving a metal like sodium or lithium in ethylamine, generating a complex ion and facilitating the partial reduction of stable structures like benzene rings.
As a strong nucleophile, ethylamine is used in synthesizing amides and introducing nitrogen atoms into molecules. It is crucial in the synthesis of certain surfactants that feature a quaternary amine bonded to a long alkyl chain.
Ethylamine can coordinate with many metals and electron-deficient atoms due to its noncovalent electron pairs. For example, it forms a salt with boron trifluoride and is used as a curing accelerator in resin synthesis.
Ethylamine can be synthesized by various methods, including the reduction of nitroethane or acetonitrile, or by reacting hexamethylenetetramine with ethyl bromide and hydrolysis. It is classified as both flammable and toxic, necessitating careful handling and appropriate safety measures such as wearing protective gloves and eyewear.
Related compounds, diethylamine, and triethylamine, with more ethyl groups attached to the nitrogen atom, have similar uses. Diethylamine, in particular, is widely used in herbicides and is liquid at room temperature, making it easier to handle.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
Hangzhou Keying Chem Co., Ltd. (HKC) is a Chinese manufacturer of fine chemicals and polymers that was established in 2010. Based in Hangzhou, Zhejiang, the company offers various fine chemicals such as reagents and catalysts, as well as polymers, active pharmaceutical ingredients (APIs), and feed additives. It also produces specialty chemicals including pesticides and natural as well as synthetic dyes. HKC products are used by clients in the agricultural and industrial sectors, including Mitsubishi Chemical, Sanofi, and Dow AgroSciences.
Hefei Home Sunshine Pharmaceutical Technology Co., Ltd, established in 2013 and headquartered in Hefei City, China, is a manufacturer specializing in both standard and custom chemical synthesis. With manufacturing facilities in Anhui, Jiangsu, Zhejiang, and Inner Mongolia, Home Sunshine Pharma offers a range of products, including active pharmaceutical ingredients (APIs), intermediates, fine chemicals, coenzymes, and nucleotides. As an ISO 9001:2015 certified company, Home Sunshine Pharma serves research institutions, universities, and industries in Europe, America, and Southeast Asia with their chemical products.
Zhengzhou Alfa Chemical Co., Ltd. (ZACC) is a manufacturer of organic chemicals and catalysts established in 2010 and based in Jiaozuo, Henan. The company primarily produces pharmaceutical and organic intermediates as well as photoelectric materials for customers in life science, polymers, dyes, and metallurgy. The company's product lineup includes condensed ring compounds, heterocyclic compounds, COFS/MOFS, and metal catalysts. These supply client corporations such as Bayer AG, Pfizer Inc., and Sumitomo Chemical Company, Ltd. ZACC also offers gram- to ton-level contract synthesis and production services.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Kat-Chem Ltd, founded in Hungary, is a distributor of chemicals. The company's product portfolio includes Ascorbic Acid and Benzalkonium Chloride, which are vital components in multiple industries and applications and custom chemical solutions. Its products are used in drug formulation and manufacturing, the sanitation and disinfection industry, and the food and beverage sector. The company is ISO 9001 registered and is a member of an international trading network named INDISGROUP representing numerous foreign companies in Hungary.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Otto Chemie Pvt. Ltd |
33.3%
|
| 2 | Guangzhou TOSUN Pharmaceutical Co., Ltd |
16.7%
|
| 3 | Biosynth |
16.7%
|
| 4 | Spectrum Chemical Mfg. Corp. |
16.7%
|
| 5 | KANTO CHEMICAL CO.,INC. |
16.7%
|
Derivation Method
The ranking is calculated based on the click share within the ethylamine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
4 | 33.3% |
|
China
|
4 | 33.3% |
|
United States of America
|
1 | 8.3% |
|
Switzerland
|
1 | 8.3% |
|
India
|
1 | 8.3% |
|
Hungary
|
1 | 8.3% |
