All Categories
This section provides an overview for triethylamine as well as their applications and principles. Also, please take a look at the list of 11 triethylamine manufacturers and their company rankings. Here are the top-ranked triethylamine companies as of December, 2024: 1.Chem-Impex International, Inc., 2.Tedia Company Inc., 3.Eurisotop.
Table of Contents
Graduated from Kyoto University, Faculty of Science, Graduate School of Science, Master (Chemistry). Joined a major general chemical manufacturer listed on the First section of the Tokyo Stock Exchange in April 2013. Engaged in analysis and scale-up of new functional polymers. Moved to another major manufacturer since May 2021. Specializes in analytical chemistry, physical chemistry, polymer chemistry, and polymer molding and processing.
https://www.linkedin.com/in/yuta-ishino-1bb143229/
Triethylamine is a tertiary amine with three ethyl groups (C2H5) attached to the nitrogen and is a clear, colorless liquid with a strong ammonia odor. Its chemical formula is (C2H5)3N, commonly abbreviated as TEA.
Triethylamine is a strong base that is easily dissolved in common organic solvents such as ethanol and acetone and is used in various industrial and laboratory applications.
It is also widely used industrially, especially in the fields of pharmaceuticals and dye intermediates.
On the other hand, triethylamine has a foul odor, is highly irritating to the skin and eyes, and is a flammable liquid classified as a hazardous material in Class 4, Petroleum No. 1. Therefore, when handling triethylamine, safety measures are required to prevent leakage, contact with the human body, fire, and explosion.
Triethylamine is a type of tertiary amine widely used in synthetic reactions because it is a soluble base in a wide range of organic solvents such as acetone, toluene, and chloroform.
Industrially, it is used as an intermediate in pharmaceuticals and dyes, polymer synthesis, and agrochemicals. It is also used as a catalyst in the gas-curing reaction of phenol resin and isocyanate resin (cold box method).
In the food industry, triethylamine is also present in squid and fish, and is added to meat products and frozen dairy products in Europe and the United States to enhance flavor.
Triethylamine is very soluble in water, ethanol, and most organic solvents. It has a boiling point of 89°C, a melting point of -114.7°C, and a density of 0.726 g/mL at 20°C. Triethylamine has a strong pungent odor, often described as similar to that of ammonia or fish.
Its chemical properties are primarily due to the presence of an amine functional group consisting of two hydrogen atoms bonded to a nitrogen atom. Because of the single pair of electrons on the nitrogen atom, Triethylamine is a strong base.
Triethylamine is also known to be a strong nucleophile, donating an electron pair to form a new chemical bond with an electrophile. For this reason, triethylamine is widely used as a reagent in organic synthesis.
Although triethylamine is not highly toxic, it can be harmful if ingested or inhaled in large quantities. Triethylamine is also flammable and should be handled with care.
Triethylamine is a tertiary amine, having three ethyl groups (-C2H5) bonded to a nitrogen atom (-N).
The nitrogen atom has a lone pair of electrons, which characterizes the properties of triethylamine. Triethylamine is a strong base because the nitrogen atom can accept a proton (H+) to form the positively charged ammonium ion (C2H5)3NH+.
Triethylamine is corrosive to the skin and eyes and is classified as Class 1 for specific target organ toxicity (single exposure) and central nervous system. In addition, as mentioned above, the substance emits a strong unpleasant odor like ammonia or rotten fish. Therefore, when using triethylamine, it is necessary to wear protective equipment and to take measures to prevent leakage.
Triethylamine is classified under various regulatory laws. Before using triethylamine, it is recommended that the hazards of the operation be assessed and that disposal procedures be clearly defined.
Triethylamine is produced primarily from ethylene, ammonia, and ethanol.
The process proceeds in the following steps
(1) Synthesis of Intermediate (Ethylenediamine)
Ethylenediamine is formed by mixing ethylene and ammonia at a temperature of approximately 200-250°C and a pressure of approximately 1-5 MPa. When this mixture is passed over a catalyst such as alumina or silica-alumina, ethylenediamine is formed.
H2C=CH2 + NH3 → H2NCH2CH2NH2
(2) Triethylamine Synthesis
Triethylamine is formed by reacting ethylenediamine with ethanol in the presence of another catalyst such as Lewis acid.
H2NCH2CH2NH2 + 2C2H5OH → (C2H5)3N + H2O + C2H4
TEA can then be separated from the reaction mixture by distillation or extraction.
*Including some distributors, etc.
Sort by Features
Sort by Area
Chem-Impex International, founded in 1981, and headquartered in Wood Dale, Illinois, is an ISO 9001:2015 certified manufacturer of laboratory chemicals. The company offers specialized quality information, technical documentation, and manufacturer audit assistance, and has invested significantly in data, fulfillment, and quality infrastructures. Orders can be processed through Electronic Data Interchange (EDI), and its warehouse is fully barcoded, ensuring fast turnaround and reduced errors. Its offerings consists of a range of products including amino acids, unnatural amino acids and its derivatives, peptide reagents, resins, nucleosides, as well as diagnostic chemicals, tissue culture reagents and antibiotics.
Oakwood Chemical is based in Estill, South Carolina. The company is a producer of a wide range of organics with particular emphasis on fluorine and sulfur compounds. The company also offers custom synthesis services and bulk quantities upon request. The company has independent operations and operations in collaboration with the University of South Carolina. The company’s suppliers include ChemCollect, Chess, KISHIDA CHEMICAL Co., Ltd., and Tetramer. The company’s featured products include boronic acids and esters, peptide coupling, fluorinated amines, and reagents for synthesis.
Tedia is a manufacturer of solvents based in Ohio where it was established in 1975. The company is involved in the processing and purifying of solvents and they also provide services for packaging these solvents in metal, glass, specialty plastics, and more along with delivery in specially designed recylcetainers to laboratories and manufacturing facilities. These products have applications for biological testing, and manufacturing along with oligonucleotide synthesis by providing chemically and optically purified Oligo Synthesis Grade Acetonitrile. The cannabis and hemp market acquires solvents for the extraction process, oil refining, material processing, and QC testing.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Sisco Research Laboratories Pvt. Ltd., established in 1975, is an Indian manufacturer and supplier of chemicals, biochemicals, and reagents, headquartered in Mumbai, Maharashtra. Supported by Food and Drug Administration (FDA)-approved manufacturing facilities, the company offers a range of products, including general laboratory chemicals and solvents, biochemical, bioreagents, and specialty fine chemicals. Their offerings also include animal cell culture, BioLit™ range of DNA and protein tools, and nanotechnology products. Additionally, SRL provides dehydrated culture media, biological ingredients, media supplements, chromogenic media, and media kits. These products serve diverse industries such as biotechnology, confectionary and food, personal care products, pharmaceuticals, and protein purification.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
BASF Corporation, established in 1986 as the North American affiliate of BASF SE, is a manufacturer of chemical products, headquarters in Florham Park, New Jersey. The company operates 11 divisions which specialize in six business segments, namely chemicals, materials (such as plastics and rubber), industrial solutions, surface technologies (including construction chemicals and coating solutions), nutrition (for human and animal), and agricultural solutions. BASF's products find extensive applications across diverse industries such as automotive and transportation, construction, consumer electronics, energy, and furniture. Additionally, the company serves the medical and pharmaceuticals, paints and coatings, power tools, pulp and paper, as well as textile industries.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Eastman Chemical was founded in 1920 and is headquartered in Kingsport, Tennessee. The company is a manufacturer and distributor of specialty chemicals, including coatings, adhesives, fibers, and plastics for industries such as automotive, medical, manufacturing, and construction. The company operates through four segments: Additives & Functional Products, Advanced Materials, Chemical Intermediates, and Fibers segments. Additives & Functional Products include food and fertilizer-based products. Advanced Materials include films and other chemicals used in transportation and electronics. Chemicals include phthalate plasticizers and other plastic products. Fibers include cigarette filters and other products.
Alkyl Amines Chemicals Limited (AAC) is an Indian supplier of amine derivatives and specialty products that was established in Navi Mumbai, Maharashtra in 1979. The company produces various aliphatic amines such as propylamines and cyclohexylamines, as well as amine derivatives (e.g. nitriles, oximes). It also offers specialty chemicals for niche applications, including tertiary and chiral amines. Aside from its products, AAC also offers contract manufacturing and custom synthesis services to its clients, which mainly consists of companies in the petrochemical, rubber, agrochemical, and textile industries.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Chem-Impex International, Inc. |
27.4%
|
| 2 | Tedia Company Inc. |
11.0%
|
| 3 | Eurisotop |
9.6%
|
| 4 | Oakwood Products, Inc |
9.6%
|
| 5 | Junsei Chemical Co.,Ltd. |
9.6%
|
| 6 | BASF |
8.2%
|
| 7 | Alkyl Amines Chemicals Limited |
6.8%
|
| 8 | nacalai |
6.8%
|
| 9 | Sisco Research Laboratories Pvt. Ltd. |
4.1%
|
| 10 | Eastman Chemical Co. |
4.1%
|
Derivation Method
The ranking is calculated based on the click share within the triethylamine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
3 | 37.5% |
|
Japan
|
2 | 25.0% |
|
India
|
2 | 25.0% |
France
|
1 | 12.5% |
