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This section provides an overview for methyl iodide as well as their applications and principles. Also, please take a look at the list of 12 methyl iodide manufacturers and their company rankings. Here are the top-ranked methyl iodide companies as of December, 2024: 1.Ajay North America, LLC, 2.PSR-LA, 3.Sensidyne, LP.
Table of Contents
Figure 1. Basic Information on Methyl Iodide
Methyl iodide, a monoiodide of methane, is known for its CAS number 74-88-4 and MITI number 2-42. Classified as a "deleterious substance" under various laws, it is recognized for its mutagenic properties and requires careful handling due to its designation under safety laws with a controlled concentration of 2 ppm.
Primarily used as a fumigant and in controlling bacterial and fungal diseases in agriculture, methyl iodide's applications extend to medical treatments for iodine deficiency and as a scintillation detector in radiation detection. Its role in livestock feed highlights its importance as an essential nutrient.
It addresses iodine deficiency, preventing goiter and hypothyroidism, and acts as a thyroid-blocking agent during nuclear incidents.
Methyl iodide serves as a scintillator material, fluorescing upon radiation exposure to detect gamma rays.
As a crucial feed supplement, it supports thyroid function and health in livestock.
This colorless to brown liquid is noted for its high toxicity and characteristic odor, with a melting point of -66.45°C and a boiling point of 42.43°C. It shows excellent solubility in organic solvents and water, but decomposes in light, requiring storage in dark, sealed containers.
Figure 2. Reaction Using Methyl Iodide
As a precursor in Grignard reactions and a methylating agent in SN2 reactions, methyl iodide's versatility is showcased in the synthesis of various organic compounds.
Despite its comparative expense, methyl iodide's ease of handling and superior methylation capacity make it a preferred choice over other halides in organic synthesis.
Figure 3. Synthesis of Methyl Iodide
Produced through the reaction of methanol with iodine and red phosphorus, methyl iodide can be purified by column chromatography using silica gel or alumina or synthesized in high yield through the reaction of potassium iodide with dimethyl sulfate and calcium carbonate.
*Including some distributors, etc.
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Zefon International was established in 1990 and is a manufacturer and supplier of air sampling equipment used to monitor indoor environmental, occupational health, and safety conditions. Based in Florida, USA, the company offers product categories such as contaminants and pollutants, air sampling equipment, industrial hygiene equipment, sampling media, and cassettes. Its popular products include air sampling pumps, cassettes, filters, and accessories. It also offers multiple services, such as technical support, training, and custom sampling programs. Zefon International's products are used by many organizations, including environmental consulting firms, industrial hygienists, and government agencies.
Ajay North America LLC, founded in 1972, is a manufacturer, supplier, and distributor of industrial chemicals. To secure a dependable source of iodine, Ajay Chemicals joint-ventured with Sociedad Química y Minera de Chile S.A. (SQM), a supplier of raw iodine. The company produces more than 70 iodine and selenium derivatives, including methyl iodide, potassium iodide, potassium iodate, calcium iodate, and many others. The Ajay-SQM Group serves a diverse range of industries, including pharmaceuticals and biotechnology, agriculture and animal feed, water treatment, and other industries that require specialty chemicals and related products.
Sensidyne is an American manufacturer and distributor of industrial air monitoring and safety equipment founded in 1983 and acquired by the German company Schauenburg International GmbH in 2008. Based in St. Petersburg, Florida, the company offers various products including aerosol and heat stress monitors, sound and vibration measurement equipment, air sampling instrumentation, and gas detector tube systems. Sensidyne also provides additional OEM, in-house calibration, and maintenance services for clients requiring additional support.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Guangzhou Reullei Pharmaceutical Technology Co., Ltd., established in 1996 and based in Guangzhou, Guangdong, China, is a manufacturer of organic chemicals. The company also does R&D and has an R&D centre, a micro reaction production laboratory and two production units in China with a capacity to produce small tests, pilot tests and mass production of chemicals. The company holds ISO 9001 quality management certification, and the department is equipped with NRM, LCMS and HPLC testing equipment. The company has applied for 53 patents, of which 28 are authorized.
Proto Chemicals Industries, since 1983, has operated as a manufacturer, exporter, and importer of iodine chemicals, feed supplements, disinfectants, antiseptic chemicals, and active pharmaceutical ingredients based in Tarapur, India. The industrial chemical product segment includes potassium hydroxide powder, potassium bromide, potassium iodide, potassium iodide, iodine crystals, and calcium iodate. Their feed supplements include sodium selenite, potassium iodate, and calcium iodate. The ingredients used in processing the chemicals are quality-tested, and the products are used in various industries such as rubber, pharmaceutical, battery manufacturing, food, and beverage.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Calibre Chemicals Pvt. Ltd. was founded in 1984 in Mumbai, Maharashtra, India, as a manufacturer of specialty chemical products. The company specializes in the production of products including ammonium perchlorate, sodium persulfate, copper iodide, perchloric acid, potassium bromide, sodium iodate, and trimethylsulfoxonium iodide (TMSI), among others. These products serve as catalysts in chemical reactions, strong acids, and components in laboratory reagents. They also act as antiseptics in wound disinfection, provide iodine in nutritional supplements, and serve as reagents in chemical synthesis. Their adaptable applications span across industries such as pharmaceuticals, chemicals, materials synthesis, and research and development.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Frontiers Media, SA, founded in the year 2007, based in Lausanne, Switzerland is a publishing media house company. Their portfolio includes scientific articles and journals which are in the form of peer review to make science open, rigorous, transparent, and efficient, and harness the power of technology for researchers. The publishing company has a diverse range of scientific articles in many academic disciplines with innovations, the latest advancements, and artificial intelligence updates.
CATO Research Chemicals Inc. is headquartered in Guangzhou City, Guangdong Province, in China. The company performs research and development and production of more than 32000 standard products and 48000 analytical reference material products for manufacturing, agriculture, pharmaceutical, and chemical markets. The company distributes a range of chemicals from raw materials to intermediates to analytical testing and customized synthetic compounds. The categories of chemicals that the company sells include plant growth regulators, polychlorinated biphenyls, volatile organic compounds, ketones, and fatty alcohols.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Ajay North America, LLC |
33.3%
|
| 2 | PSR-LA |
22.2%
|
| 3 | Sensidyne, LP |
22.2%
|
| 4 | Guangzhou Reullei Pharmaceutical Technology Co., Ltd. |
11.1%
|
| 5 | nacalai |
11.1%
|
Derivation Method
The ranking is calculated based on the click share within the methyl iodide page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
4 | 44.4% |
|
Japan
|
2 | 22.2% |
|
China
|
1 | 11.1% |
|
India
|
1 | 11.1% |
|
Switzerland
|
1 | 11.1% |
