24 Diphenylmethane Manufacturers in 2024
This section provides an overview for diphenylmethane as well as their applications and principles. Also, please take a look at the list of 24 diphenylmethane manufacturers and their company rankings. Here are the top-ranked diphenylmethane companies as of November, 2024: 1.VWR International, LLC, 2.Sarchem Laboratories Inc., 3.Glentham Life Sciences Limited.
Table of Contents
What Is Diphenylmethane?
Diphenylmethane, also known as methylenedibenzene or benzylphenyl, is an organic compound with the chemical formula C13H12. It's an aromatic hydrocarbon characterized by two phenyl groups replacing two hydrogen atoms of methane. Its CAS registration number is 101-81-5, and the univalent substituent with one hydrogen removed is specifically called the benzhydryl group.
Uses of Diphenylmethane
Diphenylmethane and its derivatives serve as substructures in various substances, particularly dyes. These derivatives are employed as raw materials for inks and dyes, with dyes made from them assigned numbers in the 41,000 range in the Color Index. Additionally, certain diphenylmethane derivatives are utilized in diabetes treatment due to their reported inhibitory effects on human SGLT2 activity and reduction of urinary glucose excretion in animals.
Properties of Diphenylmethane
Diphenylmethane has a molecular weight of 168.23, a melting point of 22-25.9°C, and a boiling point of 264°C. It appears as white needle-like crystals with an orange odor at room temperature, having a density of 1.006 g/mL. While nearly insoluble in water, it dissolves readily in ethanol and non-polar organic solvents.
Types of Diphenylmethane
Diphenylmethane is primarily sold as a reagent for research and development, available in volumes ranging from 25g to 500g. Reagent-grade products are stored below 25°C by various manufacturers.
Other Information on Diphenylmethane
1. Diphenylmethane Synthesis
Diphenylmethane is synthesized via the Friedel-Crafts reaction of benzyl chloride with benzene in the presence of a Lewis acid like aluminum chloride.
2. Reactivity of Diphenylmethane
The methylene group of diphenylmethane has an acid dissociation constant pKa of 33, making it deprotonatable by sodium amide and alkylatable with alkyl halides. This reaction proceeds with a high yield regardless of the halide's primary or secondary nature.
Diphenylmethane is photosensitive and decomposes upon contact with strong oxidizers, producing carbon monoxide and dioxide gases. Hence, it should be stored away from strong oxidizers, high temperatures, and direct sunlight, ideally in a light-shielded container in a cool, well-ventilated area below 25°C (77°F).
3. Safety and Regulations
While not subject to specific designation under certain safety laws, proper handling of diphenylmethane is essential. It requires appropriate personal protective equipment, including gloves, protective glasses, and long-sleeved clothing, along with local exhaust ventilation. Regulations regarding its transport and storage as hazardous materials should also be followed.
List of 24 Diphenylmethane Manufacturers
*Including some distributors, etc.
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VWR International, LLC
Diphenylmethane-4-carboxylic acid ≥98%
Manufacturer Overview
VWR International, LLC., founded in 1852 and based in Radnor, Pennsylvania, is a global supplier of laboratory items that have applications in life sciences and other regulated industries. In 2017, VWR was acquired by Avantor, providing critical products and services to customers in the healthcare, education, government, high technologies and applied materials industries. Its products include research equipment, chemicals, laboratory furniture, and protective clothing. The company has more than 300,000 customer locations in more than 180 countries, providing product access to scientists and research laboratories.
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Sarchem Laboratories Inc.
N,N’-(4,4′-diphenylmethane bismaleimide) | 13676-54-5
Manufacturer Overview
Sarchem Laboratories Inc., established in 1984 and based in New Jersey, United States, is a manufacturer of anti-viral drugs. The company produces products such as 4-Acetamidobenzenesulfonyl azide, β-D-Glucosamine Pentaacetate, 2-Acetyl-4-methyl pyridine, and N-Acetylprocainamide. All these products are utilized in biomedical, engineering, electronics, and energy applications. Each product is analytically tested, and the company adapts to the changing demands of the pharmaceutical, medicinal, and nutraceutical industries. The modern laboratory facilities meet the customer needs in the pre-clinical early development process from milligrams to hundreds of grams.
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Santa Cruz Biotechnology, Inc.
Diphenylmethane
Company Overview
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
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Pharmaffiliates
Benzylbenzene
Manufacturer Overview
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
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Sisco Research Laboratories Pvt. Ltd.
Diphenylmethane pure
Manufacturer Overview
Sisco Research Laboratories Pvt. Ltd., established in 1975, is an Indian manufacturer and supplier of chemicals, biochemicals, and reagents, headquartered in Mumbai, Maharashtra. Supported by Food and Drug Administration (FDA)-approved manufacturing facilities, the company offers a range of products, including general laboratory chemicals and solvents, biochemical, bioreagents, and specialty fine chemicals. Their offerings also include animal cell culture, BioLit™ range of DNA and protein tools, and nanotechnology products. Additionally, SRL provides dehydrated culture media, biological ingredients, media supplements, chromogenic media, and media kits. These products serve diverse industries such as biotechnology, confectionary and food, personal care products, pharmaceuticals, and protein purification.
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LGC Standards
Diphenylmethane
Manufacturer Overview
LGC Standards Ltd., established in 1842, is a global British manufacturer and supplier of reference standards, headquartered in Teddington, Middlesex, with offices in 20 countries worldwide. As a subsidiary of LGC Group, the United Kingdom’s National Measurement Institute, LGC Standards also serves as the Government Chemist, providing expert opinions based on independent chemical and bioanalytical measurements. Under the business unit LGC Industrial, the company offers industrial measurement tools. Additionally, their subsidiaries, including Toronto Research Chemicals Inc (TRC) of Canada, LGC Mikromol™, and Dr. Ehrenstorfer™ of Germany, develop research tools, standards for pharmaceutical quality control, and reference materials for food and environmental analysis.
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LobaChemie Pct.Ltd.
DIPHENYLMETHANE
Manufacturer Overview
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
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Alfa Chemistry
Diphenylmethane
Manufacturer Overview
Alfa Chemistry, founded in the year 2015 is based in New York, USA as a biotechnology company and manufacturer of graphene materials. Their product portfolio includes graphene oxide, CVD graphene film, graphene modification services, graphene series, graphene-like material, carbon nanomaterials, quantum dots, upcoming nanoparticles, and graphene transfer services. The company also provides services in custom manufacturing, and graphene analysis with quality assurance. The products are used in various industries which include energy, digital electronics, environment, textile, coating, and biomedical science.
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Toronto Research Chemicals
Diphenylmethane-4,4'-dicarboxylic Acid
Manufacturer Overview
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
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SimSon Pharma Limited
Diphenylmethane
Manufacturer Overview
SimSon Pharma Limited, established in 2011 and headquartered in Mumbai, India, is a manufacturer and supplier of pharmaceutical reference materials. Their product range includes drug working standards, drug impurity standards, drug metabolites, and stable isotope labeled compounds. These provide a basis for comparison and validation, enabling pharmaceutical companies to produce safe and effective medications. The company's offerings serve specific purposes, such as calibrating analytical instruments and ensuring precise analytical results, identifying and quantifying impurities in drugs, understanding drug metabolism, and developing new drug therapies.
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FUJIFILM Wako Pure Chemical Corporation
Diphenylmethane
Manufacturer Overview
FujiFilm Wako Pure Chemical Corporation, founded in 1922 and headquartered in Osaka, Japan, is a manufacturer of laboratory chemicals, specialty chemicals, and clinical diagnostic reagents. The company has three business domains, namely laboratory chemicals, specialty chemicals, and clinical diagnostic reagents, and some of its products include biochemistry reagents, blood transfusion test drugs, battery materials, polymer-related materials, and general reagents. The products are useful in various fields, including electronic, cosmetic, polymeric, pharmaceutical, and medical care. It acquired Sibayagi Co. Ltd. in 2015 and provides custom manufacturing to meet customer requirements.
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Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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MilliporeSigma
Diphenylmethane
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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HPC Standards GmbH
Diphenylmethane
Company Overview
HPC Standards GmbH, established in 1996, is a manufacturer and distributor of high-purity analytical standards for residue analysis, located in Germany. The company specializes in the manufacture of reference materials for pesticides, veterinary products, and their metabolites and stable isotope-labelled derivatives. They are ISO 9001 certified and accredited according to ISO 17034. Their products are tested according to international quality requirements and meet the highest industrial standards. They serve as a competent partner in the fields of food and environmental analysis with a wide range of products, including dyes, food-related chemicals, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and polymer additives.
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Alfa Chemical Co., Ltd.
Diphenylmethane
Company Overview
Alfa Chemical Co., Ltd., founded in 1973 and headquartered in Zhengzhou, India, is a manufacturer and supplier of organic chemicals for researching, development and manufacturing. The company provides scientific analytical chemicals, material science and life science chemicals, and catalysts from grams to kilograms. These chemicals include building blocks, reagents, pharmaceutical intermediates, dyes & indicators, produced by standards and analytical methods such as NMR, HPLC and MS. The company has a production facility, test laboratories and research centers, and provides packaging and delivery services.
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Jigs chemical
Diphenylmethane
Company Overview
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
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Central Drug House
Diphenyl methane
Company Overview
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
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Company Overview
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
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Otto Chemie Pvt. Ltd
Diphenyl methane
Distributor Overview
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
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Glentham Life Sciences Limited
Diphenylmethane
Distributor Overview
Glentham Life Sciences is based in Corsham, United Kingdom. Glentham Life Sciences is a leading supplier of fine chemicals, raw materials, reagents, and life science products. Glenthem also offers a number of services including custom packaging, call-off orders, and safety documentation. Glentham’s product offerings include chemicals such as amino acids, antibiotics, APIs, biochemicals, buffers, carbohydrates, chitin, chitosan, detergents, dyes, stains, enzymes, inorganic, peptide reagents, phytochemical, raw materials, solvents, steroids, and vitamins among others.
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Fisher Scientific
Diphenylmethane, 99%, Thermo Scientific Chemicals
Distributor Overview
Fisher Scientific UK Ltd is a supplier of laboratory chemicals, equipment, and services based in Loughborough, United Kingdom, operating as a subsidiary of Thermo Fisher Scientific, a merger of Fisher Scientific International, Inc. and Thermo Electron in 2006. With a portfolio of over 2 million products, Fisher Scientific offers chemicals, reagents, equipment and instruments, consumables, and safety products. These products cater to various sectors, including clinical diagnostic and research laboratories, pharmaceutical and biotech industries, healthcare, and government agencies. Fisher Scientific also provides business solutions like the New-Lab Start-Up program, as well as SureTRACE and SureTRACE+ for product knowledge and supply chain management.
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ChemSrc
Diphenylmethane
Distributor Overview
ChemSrc, established in 2014, is a supplier of pharmaceutical products, a chemical database platform, and a search engine. This platform serves as a gateway to an extensive repository of chemical knowledge, offering access to unique CAS-encoded product records including synthesis routes, literature references, physical and chemical properties, and supplier information. The chemical catalog spans various categories, including organic raw materials, dyes and pigments, chemical pesticides, catalysts, additives, and more. The repository information plays a vital role in supporting research and development efforts across diverse industries by fostering scientific advancements and serving as a valuable resource.
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The Good Scents Company
phenylmethylbenzene
Distributor Overview
The Good Scents Company was founded in 1980 and is headquartered in Wisconsin, United States as a supplier of fragrance and flavor manufacturing quality products. The Lermond family has been procuring raw materials for the taste and fragrance sector for nearly seven decades. Presently, the good scents company is segmented into three distinct domains. The initial source of interest is the "home page" of the good scents company, a platform designed to disseminate information about the flavor, food, and fragrance business. The second website, known as "Perflavory," has become obsolete.
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Diphenylmethane Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | VWR International, LLC |
20.7%
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| 2 | Sarchem Laboratories Inc. |
10.3%
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| 3 | Glentham Life Sciences Limited |
6.9%
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| 4 | Otto Chemie Pvt. Ltd |
6.9%
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| 5 | MilliporeSigma |
6.9%
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| 6 | ChemSrc |
3.4%
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| 7 | Matrix Fine Chemicals GmbH |
3.4%
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| 8 | LobaChemie Pct.Ltd. |
3.4%
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| 9 | The Good Scents Company |
3.4%
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| 10 | SimSon Pharma Limited |
3.4%
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Derivation Method
The ranking is calculated based on the click share within the diphenylmethane page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
- Pharmaffiliates: 2001 (23 years ago)
- Matrix Fine Chemicals GmbH: 2001 (23 years ago)
- Jigs chemical: 1998 (26 years ago)
Company with a History
- FUJIFILM Wako Pure Chemical Corporation: 1922 (102 years ago)
- SRL: 1975 (49 years ago)
- Sisco Research Laboratories Pvt. Ltd.: 1975 (49 years ago)
Diphenylmethane Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Diphenylmethane Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
India
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7 | 36.8% |
United States of America
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3 | 15.8% |
United Kingdom
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3 | 15.8% |
| United States | 1 | 5.3% |
Canada
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1 | 5.3% |
Japan
|
1 | 5.3% |
Germany
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1 | 5.3% |
China
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1 | 5.3% |
Switzerland
|
1 | 5.3% |
