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This section provides an overview for diisopropanolamine as well as their applications and principles. Also, please take a look at the list of 7 diisopropanolamine manufacturers and their company rankings. Here are the top-ranked diisopropanolamine companies as of December, 2024: 1.Jigs chemical, 2.KANTO CHEMICAL CO.,INC., 3.Labdhi Chemicals.
Table of Contents
Diisopropanolamine is an organic compound classified as a secondary amine.
It is a clear colorless liquid with an amine or ammonia-like odor at room temperature.
Diisopropanolamine is widely used as an organic synthetic raw material for pharmaceuticals, dye intermediates, rubber chemicals, herbicides, and surfactants.
As a rubber chemical, it is added as an anti-aging agent in the rubber molding process. This prevents the deterioration of rubber caused by chemical reactions induced by heat, light, and ozone.
As a herbicide, it is used as a hormone-type selective herbicide with auxin-like action. However, it is only used for herbicidal purposes in non-farming areas.
Diisopropylamine has the chemical formula C6H15N. It has a melting point of -61°C, boiling point of 84°C, and is a clear, colorless liquid at room temperature. It has an amine or ammonia-like odor. Its molecular weight is 101.193, density 0.722 g/mL, a base dissociation constant pKb of 3.43, and an acid dissociation constant pKa of 11.07 (in water) for conjugated acids.
It is soluble in ethanol, acetone, and other organic solvents, specifically methanol, ether, ethyl acetate, aromatic and aliphatic hydrocarbons, fatty acids, mineral oils, and solid oils. It is also soluble in water.
Diisopropanolamine is usually sold to the public as a reagent product for research and development. Capacity types include 25mL, 100mL, 500mL, and 2.5L, with different manufacturers offering different volume standards.
They are usually treated as reagent products that can be handled at room temperature. Reagent products are not intended for use other than for research and development purposes..
Diisopropanolamine is a stable substance under normal handling conditions, but reacts violently with oxidizing agents, posing a risk of fire or explosion. It reacts with many compounds, including organic chlorides, nitriles, and oxides.
It is corrosive to copper and zinc and their alloys, galvanized steel, and aluminum, and produces hydrogen gas. When heated or burned, it produces toxic and corrosive fumes and gases such as carbon monoxide, carbon dioxide, and nitrogen oxides.
Diisopropanolamine can be synthesized by reductive amination of acetone. Ammonia is used as a reactant against the raw material acetone in a hydrogen gas atmosphere, and a catalyst such as copper chromite is used.
It is distilled and purified in the presence of potassium hydroxide and can be stored in an inert gas atmosphere in the presence of sodium.
One of the most important organic synthetic applications of diisopropanolamine is the preparation of lithium diisopropylamide (LDA). Lithium diisopropylamide (LDA) is a substance often used in organic synthesis as a strong base.
It has an acid dissociation constant pKa of about 34 in THF and can withdraw most acidic protons, including alcohols and carbonyl compounds.
Common methods of using LDA in reactions include:
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
A.B. Enterprises was established in 1984 and is headquartered in Maharashtra, India. The company is a manufacturer and supplier of general chemicals, specialties, and industrial chemicals to a broad range of industries including food, textile, plastic, rubber, and other industries. The company exports primarily to Canada, Bahrain, and Dubai. The company’s five major product segments include petrochemicals, food chemicals, laboratory chemicals, water treatment chemicals, and fine chemicals. In addition, the company manufactures dentistry materials, pesticides, and chemical supplies.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Labdhi Chemicals was established in 2007 in Maharashtra, India, as a manufacturer and supplier of chemicals. The company offers organic chemicals, inorganic chemicals, agrochemicals, specialty chemicals, and pharmaceutical chemicals, among others. These products serve as crucial components in the formulation of medications and find utility in pharmaceutical formulation, cosmetic creation, and plastics production. They play a pivotal role in manufacturing processes and construction materials, improve agricultural practices through fertilizers, pesticides, and herbicides, and offer specialized functionalities in industries such as textiles and adhesives. The products meet the requirements of many industrial sectors, such as pharmaceutical companies, cosmetic industries, and agricultural sectors.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
Shanghai Theorem Chemical Technology Co., Ltd., established in 1997, is a company located in Shanghai, China, is a manufacturing company specializing in researching and manufacturing chemical new materials and fine chemicals. The company offers new functional materials, surfactants, polyurethane chemicals, special isocyanates, extractants, and more. They have a product chain advantage and offer professional technical support, and stable production supply with authorized ISO9001 quality management system, ISO14001 environmental management system, as well as related certifications. Their manufacturing factory with a land area of 80,000 m2, has over 300 workers, 30 engineers, 7 production workshops.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Jigs chemical |
31.6%
|
| 2 | KANTO CHEMICAL CO.,INC. |
21.1%
|
| 3 | Labdhi Chemicals |
15.8%
|
| 4 | Shanghai Theorem Chemical Technology Co., Ltd. |
10.5%
|
| 5 | MilliporeSigma |
10.5%
|
| 6 | A. B. Enterprises |
5.3%
|
| 7 | Kishida Chemical Co.,Ltd. |
5.3%
|
Derivation Method
The ranking is calculated based on the click share within the diisopropanolamine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
2 | 50.0% |
|
India
|
1 | 25.0% |
|
China
|
1 | 25.0% |
