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This section provides an overview for creatinine as well as their applications and principles. Also, please take a look at the list of 11 creatinine manufacturers and their company rankings. Here are the top-ranked creatinine companies as of December, 2024: 1.KANTO CHEMICAL CO.,INC., 2.Ennore India Chemicals, 3.Atlas Medical GmbH.
Table of Contents
Creatinine, with the chemical formula C4H7N3O and a molecular weight of 113.1179, is a metabolite from muscle creatine phosphate metabolism. It is produced in the liver, kidneys, and pancreas, and then transported to the muscles for conversion.
Creatinine serves as a biomarker in biochemical tests to assess muscle mass and renal function. Its concentration correlates with muscle mass. Variations in creatinine levels can indicate muscle mass changes or kidney dysfunction.
This non-protein nitrogen compound is highly soluble in water, not bound to plasma proteins, and has a half-life of approximately 2 hours. It's a key biological indicator for evaluating kidney function.
Creatinine has a five-membered ring structure, produced from creatine through a non-enzymatic dehydration reaction. It shares chemical similarities with guanine.
Industrial production of creatinine is limited. It involves synthesizing creatine from amino acids like glycine, followed by a dehydration reaction using acids to produce creatinine, which is then purified through chromatography or recrystallization.
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Ennore India Chemicals, established in 1995, and based in Tamil Nadu, India, is a manufacturer and supplier of industrial chemicals and cleaning solutions. The company serves various industries, including wastewater treatment, marine, power generation, and oil and gas. Ennore India Chemicals also provides fuel additives, corrosion inhibitors, descaling chemicals, chemicals for boiler water treatment, as well as chemicals for cooling towers. Their ISO 9001:2015 certification guarantees quality goods and environmentally friendly practices.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Westindiachemical, established in 1995, and headquartered in Gandhidham, India, is a manufacturer and supplier of marine chemicals, water treatment chemicals, and industrial chemicals. Its marine chemicals safeguard vessels and equipment, water treatment solutions purify water for safe use, and industrial chemicals facilitate processes in manufacturing, textiles, and more. Among their products, Corrosion Inhibitor for Central Air Chiller shields heat exchangers, Polish Preparation for Metal readies surfaces for coating, and Hold Solution aids in paint drying. Additionally, they offer Sodium Perborate Tetrahydrate for bleaching and Potassium Chloride for water softening and de-icing.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
naugraexport was established in 1951 and is a distributor and supplier of lab equipments based in Ambala Cantt, Haryana, India. The company's product portofolio offers various products such as zoom stereo binocular microscope, human anatomy models, flask erlenmeyer narrow neck glass, laser theodolite, and precision engineered cube mould. The products are used in various industries such as petrochemical, agriculture, semiconductor manufacture, pharmaceutical, and energy. The company has obtained the certificate of ISO 9001:2008 certification standards.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Anant Pharmaceuticals Pvt. Ltd., established in 2005, is a supplier of pharmaceutical impurity reference samples and custom synthesis and analytical services, based in India. The company delivers novel solutions to research and development teams. Their organic synthesis labs are equipped with modern equipment, designed with energy saving concept. Over the years, they have developed into a one-stop service provider for bespoke chemical synthesis and analytical services for a wide range of industries in India and abroad.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | KANTO CHEMICAL CO.,INC. |
40.0%
|
| 2 | Ennore India Chemicals |
20.0%
|
| 3 | Atlas Medical GmbH |
13.3%
|
| 4 | nacalai |
13.3%
|
| 5 | Vizag Chemical Internacional |
6.7%
|
| 6 | MilliporeSigma |
6.7%
|
Derivation Method
The ranking is calculated based on the click share within the creatinine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
6 | 66.7% |
|
Japan
|
2 | 22.2% |
Germany
|
1 | 11.1% |
