This section provides an overview for butyric acid as well as their applications and principles. Also, please take a look at the list of 10 butyric acid manufacturers and their company rankings. Here are the top-ranked butyric acid companies as of November, 2024: 1.BERJÉ INC, 2.Merck, 3.Peekay Agencies Pvt. Ltd.,.
Table of Contents
Butyric acid, also known as orthobutyric acid, is a four-carbon aliphatic carboxylic acid. It is an oily, colorless liquid with an unpleasant odor reminiscent of rancid butter. Even in minimal quantities, mammals can detect its scent. It has a structural isomer known as isobutyric acid.
Butyric acid occurs naturally in animal milk fat as glycerides and in plant essential oils as esters. It is also produced through the fermentation of sugars and lactic acid and can be synthesized industrially by the oxidation of butyraldehyde and butanol.
Butyric acid serves various functions, including as a raw material for varnish production, organic synthesis (e.g., 4-heptanone), and emulsifiers. It's a precursor for biofuel production and, when esterified, is used in synthetic fragrance manufacturing. Additionally, it finds applications in food processing, flavor enhancers, animal feed to boost nutrition and prevent diseases, and pharmaceuticals for treating cancer and irritable bowel syndrome.
With a density of 0.96 g/cm3 and a molecular weight of 88.11, butyric acid has a melting point of -7.9°C and a boiling point of 164°C. It is miscible with water, ethanol, and ether, and insoluble in brine, allowing for separation by salt addition. As a weak acid, its pKa is 4.82, making it slightly more acidic than acetic acid (pKa = 4.76).
Its chemical structure is CH3(CH2)2COOH, and it is sometimes referred to as butanoic acid or n-butanoic acid.
Derived from butter (Latin butyrum), butyric acid is biosynthesized during fatty acid breakdown and is widely present in nature. It contributes to the distinctive odors of body secretions, such as sebum and sweaty feet, and is found in cheese, butter, and certain plants like ginkgo biloba.
In herbivores, butyric acid is a vital energy source, produced by the anaerobic fermentation of cellulose and hemicellulose in the digestive system. It undergoes beta-oxidation to form acetyl-CoA, fueling the citric acid cycle. In the colon, it serves as a preferred energy source for colon cells and has anti-inflammatory properties, aiding intestinal repair.
Isobutyric acid, or 2-methylpropionic acid, is a structural isomer of butyric acid, with the formula (CH3)2CHCOOH. It occurs naturally, sometimes in esterified form in certain plants.
Propionic acid (CH3CH2COOH) and pentanoic acid (CH3(CH2)3COOH), also known as yoshinoic acid, are related saturated fatty acids, containing three and five carbon atoms, respectively.
*Including some distributors, etc.
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Berjé Inc. was originally founded in 1949 and is headquartered in Carteret, New Jersey. The company is a national wholesaler of over 2000 essential oils and aromatic chemicals sourced from local farmers around the world. The company has two product categories: essential & fixed oils and aromatic chemicals. Essential & fixed oils include essential oils and fixed oils while aromatic chemicals include natural aromatics and all aromatic chemicals. The company lists chemicals by four application categories which are flavor ingredients, fragrance ingredients, functional ingredients, and fragrances.
Peekay Agencies Pvt. Ltd., established in 1981, based in West Bengal, India, is a manufacturer and supplier to chemical industries. The company’s products range from 12 Hydroxystearic Acid, 2 Ethylhexanoic Acid / 2EHA, 2-EthylHexanol / 2-EH, Acetic Acid, and Barium Sulphate, among others. Chemical industries served include dyes, glass, pharmaceutical, and ceramics, among others. It has an extensive product base of more than 150 types of chemicals. The company has a vast client base of more than 5,000 esteemed customers. The company represents more than 60 companies.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Pharmachem Research & Development Laboratories, founded in 1998 and situated in Maharashtra, India, functions as a manufacturer and supplier of Laboratory & Fine Chemicals. Among its offerings are Thiomalic acid, Chloranilic acid, Para Bromo Phenol, Homidium bromide, and Safranine. Additionally, it provides basic drugs such as Hydroxy Urea, Cyclophosphamide, and Camylofine Dihydrocloride. The company boasts modern infrastructure spanning a spacious land area of 1000 square feet, well-equipped with a variety of tools, chemicals, and facilities to support research activities.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Eastman Chemical was founded in 1920 and is headquartered in Kingsport, Tennessee. The company is a manufacturer and distributor of specialty chemicals, including coatings, adhesives, fibers, and plastics for industries such as automotive, medical, manufacturing, and construction. The company operates through four segments: Additives & Functional Products, Advanced Materials, Chemical Intermediates, and Fibers segments. Additives & Functional Products include food and fertilizer-based products. Advanced Materials include films and other chemicals used in transportation and electronics. Chemicals include phthalate plasticizers and other plastic products. Fibers include cigarette filters and other products.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
RX Chemicals was founded in Mumbai, India, in 2011. RX Chemicals sells chemical-based products for many sectors including automobile, agriculture, airline, medicine, and accessories. Automobile products include carwash shampoo, compressor cleaner, and interior cleaners. Agricultural products include fungicides, herbicides, and pesticides. Airline products include exterior products such as deicing fluid, as well as interior products such as solvent cleaner. The company also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | BERJÉ INC |
23.0%
|
2 | Merck |
13.3%
|
3 | Tokyo Chemical Industry Co., Ltd. |
12.6%
|
4 | Peekay Agencies Pvt. Ltd., |
11.9%
|
5 | nacalai |
10.4%
|
6 | Eastman Chemical Co. |
8.9%
|
7 | RXChemicals |
6.7%
|
8 | Pharmachem Research & Development Laboratories |
5.9%
|
9 | Central Drug House |
5.9%
|
10 | NATIONAL ANALYTICAL CORPORATION |
1.5%
|
Derivation Method
The ranking is calculated based on the click share within the butyric acid page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
India | 4 | 57.1% |
Japan | 2 | 28.6% |
United States of America | 1 | 14.3% |