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This section provides an overview for valeric acid as well as their applications and principles. Also, please take a look at the list of 15 valeric acid manufacturers and their company rankings. Here are the top-ranked valeric acid companies as of December, 2024: 1.SRL, 2.BERJÉ INC, 3.KANTO CHEMICAL CO.,INC..
Table of Contents
Figure 1. Basic information on valeric acid
Valeric acid is a 5-carbon saturated chain carboxylic acid.
Also known as pentanoic acid, it has an unpleasant odor and was first discovered in the European herb Valerian. The dried root of Valerian has been used medicinally for centuries.
Foot odor is caused by isovaleric acid, which is an isomer of valeric acid.
Valeric acid is widely used in food flavoring, particularly in the form of esters like butyl valeric acid and pentyl valeric acid.
Although valeric acid itself has an unpleasant aroma, in small quantities it can contribute a fruity flavor and is used in fruit essences and essential oils.
It is used as a flavoring agent in various flavors, such as apple, peach, and apricot, at concentrations ranging from 4.2 to 15 ppm, and in chewing gum at about 260 ppm.
Valeric acid is well soluble in ethanol and ether, but only slightly soluble in water. It represents the lowest molecular weight carboxylic acid that is soluble in non-polar solvents. It is weakly acidic, with a pKa of 4.82, and dissolves in alkali carbonate and alkali hydroxide solutions to form salts. It is corrosive to human tissue.
Valeric acid has a melting point of -30 °F (-34.5 °C) and a boiling point of 366.8-368.6 °F (186-187 °C). Its odor is often likened to steaming socks.
The chemical formula of valeric acid is C5H10O2, with a molecular weight of 102.13 g/mol. Its structure is CH3(CH2)3COOH, and it has a density of 0.94 g/cm3. At physiological pH, it forms C4H9COO-, the conjugate base of valeric acid.
As a carboxylic acid, valeric acid reacts with alcohols to form esters and can also be used to synthesize amides, anhydrides, and acid chlorides. Pentanoyl chloride, a commonly used acid chloride, is often used as an intermediate in synthesis.
Figure 2. Synthesis of valeric acid
Valeric acid can be produced by the hydrolysis of valeronitrile and is also synthesized via the oxidation of n-amyl alcohol (1-pentanol).
In industrial processes, butyraldehyde is formed from 1-butene and syngas through hydroformylation, followed by oxidation to produce valeric acid.
Biomass-derived sugars can be converted to valeric acid via levulinic acid, a method gaining attention for biofuel production.
Figure 3. Structural isomers of valeric acid
The structural isomers of valeric acid include trimethylacetic acid, isovaleric acid, and 2-methylbutanoic acid. Trimethylacetic acid is also known as pivalic acid and neopentanoic acid, isovaleric acid as 3-methylbutanoic acid, and 2-methylbutanoic acid as hydroangelic acid.
The specific formula of trimethylacetic acid is (CH3)3CCOOH, with a density of 0.905 g/cm3. Its melting point is 95.9 °F (35.5 °C) and the boiling point is 326.8 °F (163.8 °C).
Isovaleric acid's formula is (CH3)2CHCH2COOH. It is the most common structural isomer of valeric acid found in nature and occurs in the roots of the Ominaceae species, valericaceae. It has a density of 0.925 g/cm3, a melting point of -20 °F (-29 °C), and a boiling point of 347-350.6 °F (175-177 °C).
2-methylbutanoic acid, with the formula C2H5(CH3)CHCOOH, has two optical isomers: (R)-2-methylbutanoic acid and (S)-2-methylbutanoic acid. (R)-2-methylbutanoic acid is found in cocoa beans, while (S)-2-methylbutanoic acid is present in many fruits, including apples and apricots. Its density is 0.94 g/cm3, with a melting point of -130 °F (-90 °C), and a boiling point of 348.8 °F (176 °C).
*Including some distributors, etc.
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Berjé Inc. was originally founded in 1949 and is headquartered in Carteret, New Jersey. The company is a national wholesaler of over 2000 essential oils and aromatic chemicals sourced from local farmers around the world. The company has two product categories: essential & fixed oils and aromatic chemicals. Essential & fixed oils include essential oils and fixed oils while aromatic chemicals include natural aromatics and all aromatic chemicals. The company lists chemicals by four application categories which are flavor ingredients, fragrance ingredients, functional ingredients, and fragrances.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Triown Chemie, established in 1996, is a chemical manufacturer, exporter, and trader based in Ahmedabad, India. The company offers a range of chemicals known for its purity, accurate pH-values, precise composition and extended shelf life. With an experienced professional team who ensure that their products meet international standards through rigorous testing procedures. They provide excellent products and customer service which allows them to expand their reach to regions including Europe, Asia, Latin America and China. Their transparent business practices, range of chemicals, advanced processing unit, robust R&D department and competitive pricing distinguish them from the competitors.
Hangzhou Better ChemTech Ltd, founded in 2001 and headquartered in Hangzhou, China, is a manufacturer of a range of chemicals. The company specializes in chemical production, management, application development, and brand promotion. Its product range includes vanillin, benzaldehyde, butyric acid, menthol, thymol, as well as antioxidant BHT, tributyrin, and ethyl butyrate. These products are used in various industries such as food, pharmaceuticals, cosmetics, and more. The company has service centers located in Mumbai, India, along with cooperative production bases situated in both China and India.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
Odowell is a Chinese company that specializes in the production and distribution of health wellness products. Established in 2004, the main products include blood glucose meters, blood pressure monitors, and infrared thermometers. ODOWELL provides affordable healthcare solutions to customers worldwide. With research and development, the company has earned a reputation for innovation and reliability in the healthcare industry. ODOWELL's customer satisfaction and its dedication to improving healthcare globally make it a reputable brand.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Wuhan ChemFaces Biochemical Co., Ltd, founded in China, is a supplier of a variety of different specifications of natural products to worldwide scientific research institutions and enterprises. The company's product portfolio includes a comprehensive catalog of natural products, including plant extracts, herbal compounds, biochemicals, and more. These products serve as invaluable tools for researchers in areas such as pharmaceuticals, biotechnology, agriculture, and environmental science. It also provides reference substances and active components of traditional Chinese Medicine.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ataman Kimya, established in 2006, is a distributor of chemicals based in Istanbul, Turkey. Their wide range of products includes detergents, cosmetics, disinfectants, pharmaceutical chemicals, and water treatment chemicals. They also offer textile, leather, paper, and mining chemicals. These chemicals, such as hydrogenated castor oils, ethanol, and butylene glycol, find applications in various industries, such as personal care, household cleaning, fragrance, coatings, and agriculture. The company also offers custom blending to meet specific requirements.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | SRL |
17.1%
|
| 2 | BERJÉ INC |
14.6%
|
| 3 | KANTO CHEMICAL CO.,INC. |
12.2%
|
| 4 | LobaChemie Pct.Ltd. |
9.8%
|
| 5 | Triown Chemie |
9.8%
|
| 6 | Merck |
9.8%
|
| 7 | ATAMAN Kimya A.S. INC. |
7.3%
|
| 8 | Otto Chemie Pvt. Ltd |
7.3%
|
| 9 | Wuhan ChemFaces Biochemical Co., Ltd |
4.9%
|
| 10 | Junsei Chemical Co.,Ltd. |
4.9%
|
Derivation Method
The ranking is calculated based on the click share within the valeric acid page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
5 | 38.5% |
|
Japan
|
4 | 30.8% |
|
China
|
3 | 23.1% |
|
United States of America
|
1 | 7.7% |
