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This section provides an overview for cysteamine as well as their applications and principles. Also, please take a look at the list of 10 cysteamine manufacturers and their company rankings. Here are the top-ranked cysteamine companies as of December, 2024: 1.MedChemExpress, 2.LONGCHANG CHEMICAL, 3.Spectrum Chemical Mfg. Corp..
Table of Contents
Cysteamine, a white, water-soluble solid with an unpleasant odor, features both amine and thiol functional groups. With the chemical formula HSCH2CH2NH2, it is known as 2-aminoethanethiol and has a molecular weight of 77.15 (CAS No. 60-23-1). It's typically handled as its hydrochloride salt, which appears as white to light brown crystals. Discovered in the 1950s, cysteamine was first approved in the United States in 1994 for treating cystinosis.
Cysteamine is used in pharmaceuticals to treat cystinosis by cleaving cystine's disulfide bonds. In radiotherapy, it serves as a radical scavenger. Additionally, it is used in cosmetics for skin whitening and perm solutions, acting as a reducing agent for hair's cystine bonds, though its application requires careful formulation to mitigate oxidation and odor.
Boasting a melting point of 98°C, Cysteamine decomposes before boiling and is highly soluble in water, methanol, and ethanol. It plays a crucial role in treating cystinosis and can aid in synthesizing glutathione, a potent antioxidant important for detoxifying cells.
Cysteamine is produced through the hydrolysis of 2-(2-aminoethylthio)thiazoline dihydrochloride, a process involving chloroethylamine hydrochloride and mercaptothiazoline.
Though exempt from many major domestic regulations, cysteamine is classified as acutely toxic under the GHS classification, necessitating careful handling.
Storage and handling precautions include keeping the container tightly closed in a dry, cool place, using personal protective equipment, and ensuring proper ventilation to avoid inhalation.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
Hefei TNJ Chemical Industry Co., Ltd, established in 2001, is headquartered in China. The company is a chemical manufacturer and supplier of chemicals to domestic Chinese and global consumers in four primary markets: chemicals, food, pharmaceuticals, and personal care. Chemicals include fine chemicals, agrochemicals, and other chemicals. Food includes agrochemicals, vitamins, amino acids, and food ingredients. Pharmaceuticals include specific chemicals such as Povidone iodine, Clotrimazole crystalline, and Lincomycin. The company also features a CAS databank for CAS-registered chemical compounds.
VIVAN Life Sciences Pvt. Limited, launched in 2010 in Maharashtra, India, is a manufacturer of chemical synthesis and product development products for pharmaceutical companies, contract manufacturing firms, university research labs, and contract research organizations. The company's product catalog includes building blocks, customized research chemicals, stable isotope labeled compounds, organoborane amine complexes, and specialized chemical manufacturing. It also provides custom synthesis services (CSS), chemical contract research (CCR), and contract manufacturing services. The company is accredited by CRISIL MSE 2, ISO 17034: 2016, ISO IEC 17025: 2005.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Longchang chemical Co., Ltd., is a chemical manufacturer company and was established in 1996, located in Changyi City, China. The company with a close cooperation with the School of Chemistry and Molecular Engineering of Peking University and Qilu University of Technology, is constantly developing new products, from the initial sodium silicate to the subsequent main products and by-products of petroleum resin series. In 2015, they opened a new laboratory, making a major breakthrough in flame retardant and plasticizer and light curing products. They have passed the ISO-9001 quality system certification in 2018 and passed the environmental impact assessment audit.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Apollo Scientific Ltd, established in 1993 and based in Cheshire, England, is a manufacturer and supplier of aromatic, heterocyclic, and aliphatic compounds. The company's product portfolio includes fluorinated building blocks, antibiotics for cell analysis, and silica gels. These products are used in various applications, including biotechnology, analytical laboratories for performing spectroscopic analyses for quality control, research, and testing purposes, as well as academic and research institutions. The company is ISO 9001 and ISO 14001 certified, with distributors globally in the United States, South Korea, and Japan.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | MedChemExpress |
33.3%
|
| 2 | LONGCHANG CHEMICAL |
16.7%
|
| 3 | Spectrum Chemical Mfg. Corp. |
16.7%
|
| 4 | MilliporeSigma |
16.7%
|
| 5 | Merck |
16.7%
|
Derivation Method
The ranking is calculated based on the click share within the cysteamine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
3 | 50.0% |
|
China
|
1 | 16.7% |
|
India
|
1 | 16.7% |
|
Japan
|
1 | 16.7% |
