This section provides an overview for salicylaldehyde as well as their applications and principles. Also, please take a look at the list of 16 salicylaldehyde manufacturers and their company rankings. Here are the top-ranked salicylaldehyde companies as of November, 2024: 1.KANTO CHEMICAL CO.,INC., 2.Kishida Chemical Co.,Ltd., 3.Junsei Chemical Co.,Ltd..
Table of Contents
Salicylaldehyde is a clear, colorless liquid with an almond odor.
Salicylaldehyde has the chemical formula C7H6O2, molecular weight 122.12, and CAS number 90-02-8. Other names for salicylaldehyde include the IUPAC name 2-hydroxybenzaldehyde, o-formylphenol, and 2-hydroxybenzencarbaldehyde.
Salicylaldehyde is one of the isomers of hydroxybenzaldehyde, along with 3-hydroxybenzaldehyde and 4-hydroxybenzaldehyde, which have the ortho position of benzaldehyde replaced with a hydroxy group. Salicylaldehyde is an important precursor for a variety of chelating agents, some of which are commercially important.
Salicylaldehyde has a melting point of -7°C, a boiling point of 196-197°C, and a density of 1.17 g/cm3. The solubility of salicylaldehyde in solvents is 17.1 g/kg in water, which is not very soluble. In organic solvents, it is only slightly soluble in chloroform, miscible in ethanol, and readily soluble in acetone and benzene.
Salicylaldehyde has been identified as a characteristic odorant in buckwheat. It is also one of the components of the secretions from the scent sacs of mature North American and European beavers used in perfumes.
Salicylaldehyde is used as a synthetic raw material for a variety of chemicals. Oxidation with hydrogen peroxide in the dakin reaction yields catechol. Etherification with chloroacetic acid and cyclization can also yield benzofuran, a heterocyclic compound. Salicylaldehyde can also be condensed with amines to yield the chelating ligands salen and salicylaldoxime.
Salicylaldehyde is also used as a flavoring agent. It is used in small quantities in butter, caramel, nut, cinnamon, and fruit flavors.
Salicylaldehyde can be prepared from phenol and chloroform by heating with sodium hydroxide or potassium hydroxide in the Reimer-Tiemann reaction.
C6H5OH+CHCl3+3KOH→C6H4(OH)CHO+3KCl+2H2O
Alternatively, it can be produced by condensing phenol or its derivatives with formaldehyde to produce hydroxybenzyl alcohol, which is then oxidized to aldehyde.
Precautions for handling and storage are as follows:
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Alpha Chemika, founded in 1989 and based in Mumbai, India, is a manufacturer, supplier of laboratory reagents and fine chemicals. Their products are used in multiple industries, including pharmaceutical, chemical, biotechnology, and environmental. Their product portfolio ranges from chemicals such as Silver Nitrate, Perchloric Acid, and Lanthanum Acetate to laboratory tools and equipment such as Air Inlet Tubes, Air Inlet Tubes, and Optical Components. Alpha Chemika has been able to obtain ISO 9001:2000 certification.
Hefei TNJ Chemical Industry Co., Ltd, established in 2001, is headquartered in China. The company is a chemical manufacturer and supplier of chemicals to domestic Chinese and global consumers in four primary markets: chemicals, food, pharmaceuticals, and personal care. Chemicals include fine chemicals, agrochemicals, and other chemicals. Food includes agrochemicals, vitamins, amino acids, and food ingredients. Pharmaceuticals include specific chemicals such as Povidone iodine, Clotrimazole crystalline, and Lincomycin. The company also features a CAS databank for CAS-registered chemical compounds.
Hefei Home Sunshine Pharmaceutical Technology Co., Ltd, established in 2013 and headquartered in Hefei City, China, is a manufacturer specializing in both standard and custom chemical synthesis. With manufacturing facilities in Anhui, Jiangsu, Zhejiang, and Inner Mongolia, Home Sunshine Pharma offers a range of products, including active pharmaceutical ingredients (APIs), intermediates, fine chemicals, coenzymes, and nucleotides. As an ISO 9001:2015 certified company, Home Sunshine Pharma serves research institutions, universities, and industries in Europe, America, and Southeast Asia with their chemical products.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Starsky international holdings Co., Ltd., established in 1984 and headquartered in Shanghai, China, is a manufacturer of organic and inorganic chemicals. The company provides APIs, organic and inorganic chemicals, food additives, fragrances and catalysts with customized service based on customers’ demands. It has two production facilities and complies with quality standards including ISO 9001 and 14001, GMP and Kosher. With independent export rights, the company exports its products to over 100 countries including USA, England, France, Germany and Thailand.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | KANTO CHEMICAL CO.,INC. |
29.4%
|
2 | Kishida Chemical Co.,Ltd. |
14.7%
|
3 | Junsei Chemical Co.,Ltd. |
11.8%
|
4 | nacalai |
8.8%
|
5 | Vardhman Enterprise |
5.9%
|
6 | LobaChemie Pct.Ltd. |
5.9%
|
7 | Alpha Chemika |
5.9%
|
8 | Starsky international holdings Co., Ltd. |
5.9%
|
9 | Hefei TNJ Chemical Industry Co.,Ltd. |
2.9%
|
10 | Hefei Home Sunshine Pharmaceutical Technology Co., Ltd. |
2.9%
|
Derivation Method
The ranking is calculated based on the click share within the salicylaldehyde page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
India | 5 | 38.5% |
Japan | 4 | 30.8% |
China | 4 | 30.8% |