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This section provides an overview for isobutyraldehyde as well as their applications and principles. Also, please take a look at the list of 15 isobutyraldehyde manufacturers and their company rankings. Here are the top-ranked isobutyraldehyde companies as of December, 2024: 1.Pharmaffiliates, 2.SABIC, 3.HAZMAT Resource, Inc..
Table of Contents
Isobutyraldehyde, an organic compound, has the molecular formula C4H8O and the structural formula (CH3)2CHCHCHO. Its IUPAC nomenclature is 2-methylpropanal, and its CAS number is 78-84-2. The compound has a molecular weight of 72.11, a melting point of -66°C, and a boiling point of 65°C. At room temperature, it presents as a clear, colorless liquid with an unpleasant odor.
Isobutyraldehyde is highly soluble in water, ethanol, and acetone. Its density is 0.794 g/mL, and it has a water solubility of 11 g/100mL.
Isobutyraldehyde is primarily used in organic synthesis, particularly as a raw material for neopentyl glycol (NPG) and isobutanol. Neopentyl glycol is utilized in alkyd resin paints, polyester resins, and powder coatings due to its thermal and chemical stability. Isobutanol, derived from isobutyraldehyde, is a versatile solvent and is used in the production of paint resins, isobutyl acrylate, isobutyl acetate, isobutyl methacrylate, and thinners.
Additionally, isobutyraldehyde serves as a synthetic raw material for isobutylidenediurea, DL-pantolactone, texanol, and diisopropyl ketone.
Isobutyraldehyde, a derivative of isobutane, shares a structural similarity with butyraldehyde. It has a low flash point of -17.5℃ and an ignition point of 196℃, classifying it as a highly flammable liquid or vapor. It decomposes upon heating or combustion, emitting irritating smoke and fumes. Due to its reactivity with oxidants, strong reducing agents, and strong bases, careful storage is necessary to prevent hazardous reactions.
Chemically, isobutyraldehyde can be reduced to isobutanol. It participates in the aldol reaction with formaldehyde to synthesize neopentyl glycol, and its oxidation yields methacrolein and methacrylic acid.
Isobutyraldehyde is available on the market as a reagent product for research and development, as well as industrial chemical products. Research products are offered in volumes of 25 mL, 100 mL, 500 mL, 1 L, and require refrigerated storage. Industrial products, suited for uses such as solvent and resin raw materials, are sold in larger quantities like tankers and drums to accommodate factory and facility demands.
Isobutyraldehyde can be synthesized via the hydroformylation of propylene.
*Including some distributors, etc.
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Actylis is based in Port Washington, New York, USA, and is an ISO 13485-certified custom manufacturer of chemical compounds that was established in 1978 as a subsidiary of Aceto. The company mainly produces specialty chemical products for the pharmaceutical, biopharm, and agriscience sectors. These chemical products include cell culture ingredients, active pharmaceutical ingredients (APIs), and buffering salts. It also offers excipients, adenosine for cosmetic ingredients, and vitamins for nutritional supplements. The company operates internationally, with manufacturing facilities in Germany, the United Kingdom, and India. Some of its notable clients include Novartis, Nestlé, and Estée Lauder.
Marco Rubber & Plastic Products Inc., founded in 1980 with headquarters in Seabrook, New Hampshire, USA, is a manufacturer of sealing solutions and performance rubber and plastic components. The company's product line includes O-rings, square rings, spring-energized seals, gaskets, and washers. The company also offers an extensive line of custom products, including custom-molded rubber forms, gaskets, fastener seals, grommets, and EMI RFI shielding elastomers. It also offers product packaging and stock-holding services. The company serves markets that include semiconductor, petrochemical, life sciences, military, and industrial manufacturers.
KH Neochem Co. Ltd., founded in 1966 and headquartered in Chuo-ku, Tokyo, Japan, is a manufacturer of industrial chemicals. The company operates across three core business segments, comprising of basic chemicals, performance materials, and electronic materials. Its extensive product line includes alcohols, esters, diols, and raw materials for plasticizers and resins. Utilizing high-pressure oxo equipment, the company is capable of supplying special alcohols and synthetic fatty acids like isononyl alcohol, tridecyl alcohol, and isononanoic acid.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Mitsubishi Chemical Corporation was founded in 1933 and has a head office in Tokyo, Japan. Mitsubishi Chemical Corporation provides products including chemicals, industrial gases, and health care products to customers globally. Mitsubishi Chemical Group’s performance products division manufactures and distributes. functional food materials, electronic and electrical components, specialty chemicals, and other products. Mitsubishi Chemical health care products include pharmaceuticals, drug discovery solutions, diagnostic reagents, and instruments for medical use. Mitsubishi Chemical Corporation also provides other services such as engineering, information systems, logistics, and consulting.
Saudi Basic Industries Corporation (SABIC) is a Saudi Arabian manufacturer of chemicals and intermediates established in 1976 and based in Riyadh. The company produces various basic and performance chemicals, as well as intermediates, polymers, agri-nutrients, and specialty composites. They serve companies in the industrial sectors of roughly 50 countries, with a workforce of more than 31,000 employees. SABIC has secondary large facilities in Yanbu and Al-Jubail, and is a parent company of over 38 subsidiaries and affiliate operations in Asia, Africa, Europe, and North America.
BASF Corporation, established in 1986 as the North American affiliate of BASF SE, is a manufacturer of chemical products, headquarters in Florham Park, New Jersey. The company operates 11 divisions which specialize in six business segments, namely chemicals, materials (such as plastics and rubber), industrial solutions, surface technologies (including construction chemicals and coating solutions), nutrition (for human and animal), and agricultural solutions. BASF's products find extensive applications across diverse industries such as automotive and transportation, construction, consumer electronics, energy, and furniture. Additionally, the company serves the medical and pharmaceuticals, paints and coatings, power tools, pulp and paper, as well as textile industries.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
LUXI GROUP CO., LTD., based in Liaocheng, Shandong, China, is a manufacturer and distributor of chemicals, chemical materials, and fertilizers. Its product range encompasses coal chemicals like methanol and melamine, salt chemicals such as caustic soda and benzyl chloride, and fluorosilicone chemicals like Teflon. The company has garnered numerous awards, including the "China Labor Award," for technological products, and contributions to the chemical industry, making them a player in China's chemical manufacturing landscape.
Eastman Chemical was founded in 1920 and is headquartered in Kingsport, Tennessee. The company is a manufacturer and distributor of specialty chemicals, including coatings, adhesives, fibers, and plastics for industries such as automotive, medical, manufacturing, and construction. The company operates through four segments: Additives & Functional Products, Advanced Materials, Chemical Intermediates, and Fibers segments. Additives & Functional Products include food and fertilizer-based products. Advanced Materials include films and other chemicals used in transportation and electronics. Chemicals include phthalate plasticizers and other plastic products. Fibers include cigarette filters and other products.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
HAZMAT Resource, Inc., located in Irvine, California, USA, is a distributor of hazardous materials response equipment and materials. They specialize in personal protective equipment (PPE), testing devices, and technical reference materials for hazardous materials (hazmat) response. Their product range includes PPE such as suits, gloves, boots, and respirators to safeguard hazmat responders from dangerous substances. They offer various testing devices like meters, detectors, and kits for precise identification and measurement of hazardous materials. Additionally, the company provides technical reference materials like books, manuals, and software, equipping responders with essential knowledge on hazardous material properties and safe handling procedures.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | HAZMAT Resource, Inc. |
27.3%
|
| 2 | Pharmaffiliates |
18.2%
|
| 3 | SABIC |
18.2%
|
| 4 | BASF |
18.2%
|
| 5 | Actylis |
9.1%
|
| 6 | Merck |
9.1%
|
Derivation Method
The ranking is calculated based on the click share within the isobutyraldehyde page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
4 | 44.4% |
|
United States of America
|
2 | 22.2% |
|
India
|
2 | 22.2% |
|
China
|
1 | 11.1% |
