This section provides an overview for benzoyl chloride as well as their applications and principles. Also, please take a look at the list of 12 benzoyl chloride manufacturers and their company rankings. Here are the top-ranked benzoyl chloride companies as of November, 2024: 1.Sheetal Chemicals, 2.Junsei Chemical Co.,Ltd., 3.Prathamesh Industries.
Table of Contents
Benzoyl chloride, a colorless liquid with a pungent odor, is a simple aromatic acid halide derived from benzoic acid. It has a molar mass of 140.6 g/mol, with melting and boiling points of -1°C and 197°C, respectively. Its CAS number is 98-88-4.
This compound can be produced through the chlorination of benzoic acid using phosphorus pentachloride, thionyl chloride, or phosgene. Another method involves the partial hydrolysis of trichloromethylbenzene.
Benzoyl chloride reacts with water to form benzoic acid and hydrogen chloride, necessitating careful storage to prevent exposure to moisture. It is toxic and can irritate the skin, eyes, and mucous membranes. Decomposition produces corrosive and highly toxic gases like hydrogen chloride and sulfur dioxide. Proper ventilation and explosion-proof equipment are essential due to the risk of forming explosive mixtures above 72°C.
Benzoyl chloride is utilized in various applications, including:
Its reactive thionyl chloride moiety makes it a versatile reagent in esterification reactions with alcohols and in producing benzoyl derivatives with phenol, amines, and other nucleophiles. It acts as a benzoylating agent, facilitating carbon-carbon and heteroatom bond formation. Moreover, it's involved in the Kurtius transition for synthesizing amines, including routes to pharmaceuticals like Tamiflu, and is used in Friedel-Crafts reactions.
By reacting with sodium peroxide, benzoyl chloride can be converted into benzoyl peroxide, a radical polymerization initiator and curing agent for unsaturated polyesters. It also serves as a synthetic intermediate for dyes, chemicals, and fragrances, highlighting its importance in the chemical industry.
Regulated under various laws, benzoyl chloride is categorized as a flammable liquid and a deleterious substance, emphasizing the need for cautious handling and compliance with safety regulations.
*Including some distributors, etc.
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Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Sheetal Chemicals is an Indian manufacturer and supplier of industrial and specialty chemicals that was established in Mumbai, Maharashtra in 1997. The company produces various chemical products including industrial chemicals (e.g. solvents), active pharmaceutical ingredients (APIs), and specialty chemicals like catalysts and pesticides. It also offers imported chemicals such as hydroquinone and benzoyl chloride. Sheetal Chemicals chiefly serves clients in India’s agricultural and pharmaceutical sectors, as well as its pigments and dyes industry.
Gunjal Industries, headquartered in Ankleshwar, Gujarat, India, has operated since 2017 as a manufacturer, exporter, and supplier of intermediates, APIs, and chemicals. They offer various types of chemicals, including specialty, industrial organic, and inorganic chemicals. The active ingredients and intermediates produced by the company are helpful in producing various organic compounds in the pharmaceutical, perfume, resin, dye, and agrochemical industries. Gunjal Industries' products include potassium chloride, magnesium sulphate, benzophenone, magnesium turnings, and manganese oxide. The company also offers testing, processing, and packaging services for all products clients order.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Joshi Agrochem Pharma, established in 1971 and based in Mumbai, India, is a manufacturer, supplier, and exporter of various chemicals, solvents, and metals. The company maintains a stock of agro fertilizers, pesticides, and pharmaceuticals. It has a readily available inventory of 2,000 products, including agrochemicals, solvents, and APIs. These products are utilized in a range of industries, such as automobile, aerospace, and agriculture. The company holds ISO 9001 and ISO 14001 certification and operates as part of the Joshi Group of companies, which is comprised of four companies that are segmented to ensure smooth business in varying domains.
ANYTOP CO., LTD., founded in 2012 and headquartered in Yangzhou, Jiangsu, China, is a manufacturer, distributor, and supplier of mosquito repellant parts and chemicals. The company offers toluic acid, aluminum phosphide pills, simple mosquito paper mats, bottle sets, and methyl benzoyl chloride. The products are used locally and sent to Europe, America, Australia, and Asia markets. The company is a member of the China Council for the Promotion of International Trade.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
RX Chemicals was founded in Mumbai, India, in 2011. RX Chemicals sells chemical-based products for many sectors including automobile, agriculture, airline, medicine, and accessories. Automobile products include carwash shampoo, compressor cleaner, and interior cleaners. Agricultural products include fungicides, herbicides, and pesticides. Airline products include exterior products such as deicing fluid, as well as interior products such as solvent cleaner. The company also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Sheetal Chemicals |
21.4%
|
2 | Junsei Chemical Co.,Ltd. |
19.0%
|
3 | Prathamesh Industries |
16.7%
|
4 | Gunjal Industries |
11.9%
|
5 | RXChemicals |
7.1%
|
6 | Central Drug House |
7.1%
|
7 | ANYTOP CO., LTD. |
4.8%
|
8 | Remedy Labs |
4.8%
|
9 | Kishida Chemical Co.,Ltd. |
4.8%
|
10 | JOSHI AGROCHEM PHARMA PVT LTD |
2.4%
|
Derivation Method
The ranking is calculated based on the click share within the benzoyl chloride page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
India | 7 | 63.6% |
Japan | 3 | 27.3% |
China | 1 | 9.1% |