This section provides an overview for selenium dioxide as well as their applications and principles. Also, please take a look at the list of 15 selenium dioxide manufacturers and their company rankings. Here are the top-ranked selenium dioxide companies as of November, 2024: 1.Oakwood Products, Inc, 2.GFS Chemicals, Inc., 3.Santa Cruz Biotechnology, Inc..
Table of Contents
Figure 1. Basic Information on Selenium Dioxide
Selenium dioxide, also known as selenous anhydride, is an oxide of selenium formed by burning selenium or oxidizing it with nitric acid. It appears as a colorless crystal at room temperature.
Under the Industrial Safety and Health Law, selenium dioxide is classified as a hazardous and toxic substance. It is also recognized as a chemical hazard under the Labor Standards Law, a class 1 designated chemical substance under the PRTR Law, and a toxic substance under the Poisonous and Deleterious Substances Control Law.
Selenium dioxide serves as an oxidizing agent in organic chemistry, enabling the synthesis of compounds that are challenging to produce by other means. It is particularly useful for oxidizing carbonyl compounds, olefins, acetylenes, and alcohols. Additionally, it is used in glassmaking to decolorize glass with impurities, giving it a colorless appearance.
At room temperature, selenium dioxide forms colorless, needle-like crystals. It sublimates at 315°C into a yellowish-green gas and melts at 340°C in a sealed tube, turning into a blue liquid. It dissolves in water at 73.3 g per 100 g at 25°C, emits a characteristic unpleasant odor, and is highly toxic. The LD50 values are 23.3 mg/kg for mice and 68.1 mg/kg for rats when administered orally. It can be absorbed through inhalation and skin contact, necessitating careful handling.
Selenium dioxide has a chemical formula of SeO2, a formula weight of 110.96 g/mol, and a density of 3.95 g/cm3. It forms chain-like polymers at room temperature, with alternating selenium and oxygen atoms. The polymer's selenium atoms are pyramidal, with oxide groups at the ends. In the gas phase, it exists as dimers and oligomers, and at high temperatures, it becomes monomeric, adopting a curved structure similar to that of sulfur dioxide.
Figure 2. Reactions of Selenium Dioxide
When reduced by ammonia, selenium dioxide forms elemental selenium. Oxidation by hydrogen peroxide or oxygen in nitric acid yields selenite.
Figure 3. Reaction using Selenium Dioxide
As a valuable reagent in organic synthesis, selenium dioxide can oxidize various organic compounds, such as converting paraldehyde to glyoxal and cyclohexanone to 1,2-cyclohexanedione. The oxidation reactions, including Riley oxidation, highlight its utility in synthesizing complex molecules like 1,2,3-selenadiazoles from acylated hydrazone derivatives.
*Including some distributors, etc.
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Oakwood Chemical is based in Estill, South Carolina. The company is a producer of a wide range of organics with particular emphasis on fluorine and sulfur compounds. The company also offers custom synthesis services and bulk quantities upon request. The company has independent operations and operations in collaboration with the University of South Carolina. The company’s suppliers include ChemCollect, Chess, KISHIDA CHEMICAL Co., Ltd., and Tetramer. The company’s featured products include boronic acids and esters, peptide coupling, fluorinated amines, and reagents for synthesis.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Ereztech was founded in 2010 and headquartered in Johns Creek, Georgia with manufacturing in Sheboygan Falls, Wisconsin. Ereztech is a provider of organometallic precursor R&D and manufacturing services for global customers. Ereztech in ISO 9001:2015 certified. Ereztech offers over 1200 chemical compounds and materials including high purity silver sulfate and aluminum nitrate. In addition to these materials, Ereztech offers full-service production and packaging from synthesis samples to high-volume manufacturing quantities. This includes fully customized vessel cleaning procedures, detailed, custom workflow processes specific to each material and vessel, inventory management system, and beginning to end quality control.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Sisco Research Laboratories Pvt. Ltd., established in 1975, is an Indian manufacturer and supplier of chemicals, biochemicals, and reagents, headquartered in Mumbai, Maharashtra. Supported by Food and Drug Administration (FDA)-approved manufacturing facilities, the company offers a range of products, including general laboratory chemicals and solvents, biochemical, bioreagents, and specialty fine chemicals. Their offerings also include animal cell culture, BioLit™ range of DNA and protein tools, and nanotechnology products. Additionally, SRL provides dehydrated culture media, biological ingredients, media supplements, chromogenic media, and media kits. These products serve diverse industries such as biotechnology, confectionary and food, personal care products, pharmaceuticals, and protein purification.
RETORTE GmbH is a manufacturer of 99.999% pure selenium and selenium compounds and founded in Middle Franconia, Germany, in 1949, The company's refined selenium complies with environmental standards and is sold to industrial poductions globlally. Currently, it serves 20 different industries in 50 countries. The 500 customers that benefit from these products are from the glass, pharmaceutical, optical, and steel industries. Additionally, it also manufactures other chemicals, non-ferrous metals, and fabricated metal products.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
FujiFilm Wako Pure Chemical Corporation, founded in 1922 and headquartered in Osaka, Japan, is a manufacturer of laboratory chemicals, specialty chemicals, and clinical diagnostic reagents. The company has three business domains, namely laboratory chemicals, specialty chemicals, and clinical diagnostic reagents, and some of its products include biochemistry reagents, blood transfusion test drugs, battery materials, polymer-related materials, and general reagents. The products are useful in various fields, including electronic, cosmetic, polymeric, pharmaceutical, and medical care. It acquired Sibayagi Co. Ltd. in 2015 and provides custom manufacturing to meet customer requirements.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
GFS Chemicals was founded in 1928 and is based in Columbus, Ohio. GFS Chemicals is an ISO 9001:2015 certified manufacturer as well as a supplier of specialty and fine chemicals, serving customers worldwide. GFS serves an array of industries including pharmaceutical, electronics, energy, fragrances, agrichemical, and specialty polymers. GFS Chemicals supplies over 8,600 chemicals in the United States, available in both small and large quantities. GFS Chemicals also offers Karl Fischer reagents, PPT/PPB trace analysis grade acids, turbidity standards, and other high-quality materials.
Nanografi Nano Technology is a manufacturer and supplier of nanomaterials and nanotechnology-based products across several industries. The company was established in 2011 and has offices in the United States, Germany, Estonia, and Turkey. Nanografi offers various graphane-based products and other materials including carbon materials, sputtering materials, electrode materials for batteries and supercapacitors as well as industrial equipment. The company also produces Anti-Friction Coatings for metal, plastic, and elastomer parts. They have a wide range of equipment for research institutes, laboratories, and biotechnology companies.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
ALADDIN is a manufacturer and supplier of research and development reagents that was established in Shanghai, China, in 2009. Its biochemical reagents are used in the life sciences, materials science, and chemistry fields. The company manufactures drug target ligands, antibodies, and proteins as well. It also supplies testing services and laboratory equipment for high-end users. It works in technological, biological, and scientific, research too. Its inventory is used in the biological science and analytical chemistry industries.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Oakwood Products, Inc |
13.0%
|
2 | Ereztech LLC |
10.9%
|
3 | GFS Chemicals, Inc. |
10.9%
|
4 | Santa Cruz Biotechnology, Inc. |
10.9%
|
5 | RETORTE GmbH |
8.7%
|
6 | Nanografi Nano Technology |
8.7%
|
7 | ALADDIN |
6.5%
|
8 | Tokyo Chemical Industry Co., Ltd. |
6.5%
|
9 | Junsei Chemical Co.,Ltd. |
6.5%
|
10 | KANTO CHEMICAL CO.,INC. |
6.5%
|
Derivation Method
The ranking is calculated based on the click share within the selenium dioxide page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 6 | 54.5% |
United States of America | 3 | 27.3% |
India | 1 | 9.1% |
Germany | 1 | 9.1% |