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This section provides an overview for benzophenone as well as their applications and principles. Also, please take a look at the list of 11 benzophenone manufacturers and their company rankings. Here are the top-ranked benzophenone companies as of December, 2024: 1.CRITICAL CATALYST, 2.Campaign for Safe Cosmetics, 3.Consumer Product Testing Company.
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Benzophenone, a white or almost white crystalline powder, is notable for its sweet aroma. As a key aromatic ketone compound, it serves as an essential building block in organic chemistry, often referred to as diphenyl ketone.
With a melting point of 48~50°C and a boiling point of 305.4°C, benzophenone exhibits significant thermal stability. Its flash point is 143°C, and it has a density of 1.11 g/cm3. Soluble in acetone and ethanol, it remains virtually insoluble in water. Structurally, it comprises two benzene rings linked by a carbonyl group, known as Ph2CO, with a molecular weight of 182.22 and CAS number 119-61-9.
Its ability to absorb ultraviolet light makes it an effective photoinitiator in polymerization processes.
Benzophenone-based UV absorbers protect plastics and paints from UV damage by converting UV light into less harmful forms of energy.
It is utilized alongside sodium metal to dehydrate solvents, with the blue color of benzophenone ketyl serving as an indicator for the dehydration process completion.
In chemical biology, benzophenone is attached to small molecules to form covalent bonds with interacting proteins upon UV irradiation, aiding in the identification of protein interactions.
Derivatives of benzophenone find use as sunscreen ingredients, in organic synthesis, and as intermediates for pharmaceuticals.
Commercially, benzophenone is produced via the copper-catalyzed oxidation of diphenylmethane. Laboratory synthesis can involve hydrolysis of dichlorodiphenylmethane or the Friedel-Crafts reaction of benzoyl chloride with benzene.
Benzophenone is recognized as a hazardous substance under various laws, requiring careful management and handling according to various safety regulations.
Precautions include storing in a cool, dark place, using protective gear, and adhering to safe handling practices to prevent dust dispersion and avoid skin or eye contact.
*Including some distributors, etc.
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Consumer Product Testing Company, founded in 1975 and based in Fairfield, New Jersey, is a supplier of laboratory testing solutions to the chemical, pharmaceutical, cosmetic, and personal care industries. The company offers lab testing services to companies to ensure they offer safe products to their consumers. Services available include toxicology, photobiology, microbiology, clinical safety, and analytical chemistry. Other solutions include performance claims validation, in-vitro safety, and custom consulting services. Markets served include cosmetics, personal care, pharmaceuticals, medical devices, and dietary supplements. The company offers testing and consulting services to manufacturers on six continents in compliance with FDA, EPA, and ISO regulations.
Actylis is based in Port Washington, New York, USA, and is an ISO 13485-certified custom manufacturer of chemical compounds that was established in 1978 as a subsidiary of Aceto. The company mainly produces specialty chemical products for the pharmaceutical, biopharm, and agriscience sectors. These chemical products include cell culture ingredients, active pharmaceutical ingredients (APIs), and buffering salts. It also offers excipients, adenosine for cosmetic ingredients, and vitamins for nutritional supplements. The company operates internationally, with manufacturing facilities in Germany, the United Kingdom, and India. Some of its notable clients include Novartis, Nestlé, and Estée Lauder.
The Campaign for Safe Cosmetics, launched in 2004 and headquartered in San Francisco, CA, is a community of public health, environmental, religious, educational, and consumer groups. The coalition's mission is to protect the health of workers and consumers by requiring the cosmetics industry to remove all chemicals known or suspected of causing reproductive or carcinogenic health hazards. The coalition works with signatory organizations, businesses, and individuals to advocate for safer health and beauty products. The campaign is part of BCPP, a science-backed advocacy organization whose goal is to prevent breast cancer by removing environmental factors associated with the disease.
Mettler Toledo was incorporated in 1945 in Toledo, Ohio, and is today headquartered in Greifensee, Switzerland. Mettler Toledo is a manufacturer of various analytical instruments for use in laboratories, industrial and manufacturing, and food retailing applications to customers globally. Mettler Toledo offers many products across product lines for uses such as product inspection, process analytics, jewelry scales, moisture analyzers, and software for laboratory weighing. Mettler Toledo also offers numerous accessories such as density kits, hands-free accessories, weighing tables, and weight accessories.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
CRITICAL CATALYST, founded in 2018 and located in London, UK, is a supplier of technical and regulatory consulting services in the medical and cosmetics industries. The company serves manufacturers and distributors in various industries globally. It offers consulting services in health impact assessment, medical software and apps, in-vitro diagnostics, dietary supplements, and public health and regulatory systems. The company operates in North America, Latin America, the European Union, the United Kingdom, Southeast Asia, and the Middle East markets in compliance with all country-specific regulatory requirements.
MDPI was founded in 1996 and is based in Basel, Switzerland. The company is a pioneer in scholarly, open-access publishing, featuring 417 peer-reviewed journals and 9 conference journals with over 115,000 academic contributors. The company’s journals fall into 10 subjects including biology, economics, medicine, physical sciences, and public health. The company’s pear review system is a dingle-blind assessment with at least two independent reviewers, followed by a final decision of acceptance or rejection by the editor-in-chief. Authors may appeal editorial decisions in case of rejection of articles.
Environmental Working Group (EWG) is a not-for-profit consumer protection and environmental health organization based in Washington D.C. Founded in 1993, the organization engages in scientific analysis of various industrial and consumer products including pesticides, cosmetics, and food products, publishing their findings in quarterly reports and databases. The organization is actively engaged in a certification program for products and companies that meet their transparency and health standards, which are updated annually. Notable EWG projects include their Shopper's Guide to Pesticides in Produce, a state-by-state Tap Water Database, and nationwide campaigns promoting clean energy and advocating against citizens’ exposure to harmful chemicals.
CATO Research Chemicals Inc. is headquartered in Guangzhou City, Guangdong Province, in China. The company performs research and development and production of more than 32000 standard products and 48000 analytical reference material products for manufacturing, agriculture, pharmaceutical, and chemical markets. The company distributes a range of chemicals from raw materials to intermediates to analytical testing and customized synthetic compounds. The categories of chemicals that the company sells include plant growth regulators, polychlorinated biphenyls, volatile organic compounds, ketones, and fatty alcohols.
Aako B.V., a chemical distributor headquartered in Leusden, Netherlands, was founded in 1945 as General American Dye Company, originally importing dye chemicals from the United States. The company provides a wide range of specialty chemicals for product manufacturing, such as Emulsogen CIO 050 and Genamin CTAC 50 for cleaning, and MISTRAL 80 WP for crop protection. Other chemicals include calcium formate for animal feed, calcium chloride for food, and Jarocare BKL for personal care products. The company offers sourcing, supply chain, formulation, and legislative services adhering to industry standards and collaborates with suppliers like Epolin Inc. and James Robinson Speciality Ingredients Ltd.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | CRITICAL CATALYST |
16.7%
|
| 2 | Campaign for Safe Cosmetics |
16.7%
|
| 3 | Consumer Product Testing Company |
12.5%
|
| 4 | Environmental Working Group |
12.5%
|
| 5 | Actylis |
12.5%
|
| 6 | Mettler-Toledo |
12.5%
|
| 7 | Toronto Research Chemicals |
8.3%
|
| 8 | MDPI |
4.2%
|
| 9 | Alfa Aesar, Thermo Fisher Scientific. |
4.2%
|
Derivation Method
The ranking is calculated based on the click share within the benzophenone page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
3 | 37.5% |
|
Germany
|
1 | 12.5% |
|
Canada
|
1 | 12.5% |
|
United Kingdom
|
1 | 12.5% |
|
Portugal
|
1 | 12.5% |
|
Switzerland
|
1 | 12.5% |
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1 products
ChemFine International Co., Ltd.
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