This section provides an overview for fluorobenzene as well as their applications and principles. Also, please take a look at the list of 15 fluorobenzene manufacturers and their company rankings. Here are the top-ranked fluorobenzene companies as of November, 2024: 1.MUBY CHEMICALS, 2.KANTO CHEMICAL CO.,INC., 3.Manus Aktteva Biopharma LLP.
Table of Contents
Fluorobenzene is an organic compound with the molecular formula C6H5F. The CAS registration number is 462-06-6. It has a molecular weight of 96.1, a melting point of -44 °C, and a boiling point of 85 °C. It is characterized by a peculiar odor. It has a density of 1.025 g/ml. It is miscible with ether, extremely soluble in ethanol and acetone, but virtually insoluble in water.
Fluorobenzene is a useful raw material for organofluorine compounds. It is used as a synthetic raw material and extractant for organic compounds such as agrochemicals and pharmaceuticals.
It is also considered a relatively inert compound due to the strength of its carbon-fluorine bond and is often used as an organic solvent. Although its melting point is much lower than that of benzene (5.5°C), its boiling point is almost the same. However, it is important to note that fluorobenzene can crystallize by coordinating with metal complexes.
Fluorobenzene can be synthesized on a laboratory scale by the thermal decomposition of benzenediazonium tetrafluoroborate. Heating solid benzenediazonium tetrafluoroborate produces two volatiles, boron trifluoride, and fluorobenzene, which can be separated by their different boiling points.
Another synthetic method exists in which benzenediazonium chloride is made into a piperidine salt, which is then treated with hydrofluoric acid.
Fluorobenzene is more likely to react with electrophiles at the para position due to the electron-donating nature of the fluorine atom. Hence, the conversion to 1-bromo-4-fluorobenzene proceeds in a relatively high yield. The CF bond is also a relatively stable bond due to its high bond energy.
Due to its relatively stable compound, it is used as a solvent, but it can also be coordinated with metal complexes, causing them to crystallize.
Although it is considered stable under normal storage conditions, it should be kept away from high temperatures, direct sunlight, and flames.
Fluorobenzene is sold mainly as reagent products for research and development and as products for the chemical industry.
In reagents for research and development, it is available in different volumes such as 5g, 25g, 100g, and 500g. These reagent products can be handled at room temperature. The main uses of these reagents are raw materials for organic synthesis. a reagent product is fluorobenzene-d5, in which the hydrogen atom is replaced by a deuterium.
In addition, products for the chemical industry are supplied from gram scale to ton scale. Large volumes are often handled in drums and tanks, and due to the large scale, they are usually handled in a cool, dark place.
Fluorobenzene is a highly flammable liquid with a low flash point of -8℃.
In terms of hazards to the human body, serious eye damage and germ cell mutagenicity tests have been conducted, and there is a risk of hereditary diseases.
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Alpha Chemika, founded in 1989 and based in Mumbai, India, is a manufacturer, supplier of laboratory reagents and fine chemicals. Their products are used in multiple industries, including pharmaceutical, chemical, biotechnology, and environmental. Their product portfolio ranges from chemicals such as Silver Nitrate, Perchloric Acid, and Lanthanum Acetate to laboratory tools and equipment such as Air Inlet Tubes, Air Inlet Tubes, and Optical Components. Alpha Chemika has been able to obtain ISO 9001:2000 certification.
Manus Aktteva Biopharma LLP, established in 2010 and headquartered in Ahmedabad, India, is a manufacturer, supplier, and exporter of pharmaceutical APIs, intermediates, and specialty chemicals. Their wide-ranging products cater to industries such as pharmaceutical, nutraceutical, and biotechnology. They offer Active Pharmaceutical Ingredients (APIs), the fundamental components used in various drug formulations, such as antibiotics, cardiovascular drugs, and anti-inflammatory drugs. The company also supplies specialty chemicals with unique properties applicable to diverse industries, from plastics to cosmetics manufacturing. Furthermore, the company offers custom synthesis services to meet the specific needs of their customers.
MUBY CHEMICALS, established in 1976, is a manufacturer and supplier of chemicals and excipients used in pharmaceuticals, cosmetics & personal care, agrochemical, and textile industries. Based in Ankleshwar, Gujarat, India, the company offers Shale gas hydraulic Fracturing Chemicals such as ammonium persulfate, diverting agents, inhibitors, ATMP phosphonate, and encapsulated gel breakers. Some food analytical reagent chemicals include benzyl alcohol, calcium oxide, boric acid, carbamide peroxide, and lithium carbonate. The company is GLP-approved, Kosher Certified, "REACH" Registered, and ISO-9001 Certified.
A.B. Enterprises was established in 1984 and is headquartered in Maharashtra, India. The company is a manufacturer and supplier of general chemicals, specialties, and industrial chemicals to a broad range of industries including food, textile, plastic, rubber, and other industries. The company exports primarily to Canada, Bahrain, and Dubai. The company’s five major product segments include petrochemicals, food chemicals, laboratory chemicals, water treatment chemicals, and fine chemicals. In addition, the company manufactures dentistry materials, pesticides, and chemical supplies.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Hridaan Pharma Chem is a manufacturer of organic solvents, inorganic chemicals, and specialty chemicals, established in 2002 and headquartered in Mumbai, India. Their product range includes organic solvents such as methanol, ethanol, and isopropanol, inorganic chemicals such as sulfuric acid and nitric acid, and specialty chemicals such as flavoring agents and electronic chemicals. These products serve diverse industries with applications ranging from pharmaceuticals, plastics, and water treatment to food flavoring, fragrance, and electronics manufacturing. Hridaan Pharma Chem holds the Trust Seal Verified, indicating that the company has been authenticated and verified by IndiaMART.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Joshi Agrochem Pharma, established in 1971 and based in Mumbai, India, is a manufacturer, supplier, and exporter of various chemicals, solvents, and metals. The company maintains a stock of agro fertilizers, pesticides, and pharmaceuticals. It has a readily available inventory of 2,000 products, including agrochemicals, solvents, and APIs. These products are utilized in a range of industries, such as automobile, aerospace, and agriculture. The company holds ISO 9001 and ISO 14001 certification and operates as part of the Joshi Group of companies, which is comprised of four companies that are segmented to ensure smooth business in varying domains.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
Shanghai Freemen Chemicals Co., Ltd., established in 1995 and headquartered in Shanghai, China, serves as a supplier of chemical products such as titanium dioxide, fluoride polymers, epoxy resins, and fine chemicals. The company offers a comprehensive product line, featuring ethyl vinyl ether, pivalic acid, aloe emodin, 3-aminomethyl oxetane, trimethyl orthoformate, and more. These products cater to industries such as fine chemicals, pharmaceuticals, agrochemicals, nutrition, and beyond. The company boasts a range of customers, including India Pesticide Limited, Biocon, Honeywell, Deccan, Syngenta, and others.
India Fine Chemicals, founded in 1978 and headquartered in Taito-ku, Tokyo, Japan, is a distributor and supplier of chemicals, functional materials, food additives, as well as a planner and developer of health foods. The company offers an extensive range of products, including sodium vinylsulfonate 25% water solution, sodium cumene sulfonate, N-dimethyl-1,3-propanediamine, and diethyl sulfate. These chemicals serve various industries, including pharmaceuticals, agrochemicals, cosmetics, dyes, and flavors. The company also offers a range of services, including information about chemicals, a chemical search engine, product analysis, and contract development.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | MUBY CHEMICALS |
27.3%
|
2 | Alfa Aesar, Thermo Fisher Scientific. |
18.2%
|
3 | KANTO CHEMICAL CO.,INC. |
18.2%
|
4 | Manus Aktteva Biopharma LLP |
9.1%
|
5 | Alpha Chemika |
9.1%
|
6 | Kishida Chemical Co.,Ltd. |
9.1%
|
7 | nacalai |
9.1%
|
Derivation Method
The ranking is calculated based on the click share within the fluorobenzene page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
India | 8 | 66.7% |
Japan | 3 | 25.0% |
United Kingdom | 1 | 8.3% |