All Categories
History
This section provides an overview for fluorescein sodium as well as their applications and principles. Also, please take a look at the list of 15 fluorescein sodium manufacturers and their company rankings. Here are the top-ranked fluorescein sodium companies as of December, 2024: 1.CFM OSKAR TROPITZSCH GMBH, 2.Central Drug House, 3.Guangzhou Fischer Chemical Co.,Ltd.
Table of Contents
Fluorescein sodium, also known as uranine, is a dark brown or orange powder, odorless and soluble in water, and ethanol, but almost insoluble in diethyl ether. It exhibits a bright yellow color in acidic conditions and fluoresces in strongly acidic or alkaline conditions.
Chemical formula: C20H10Na2O5, Molecular weight: 376.28, Melting point: 315℃, Flashpoint: 218℃, CAS number: 518-47-8.
Used as a contrast agent in medical imaging, tracer in microbiology, and manufacturing as colorants, optical brighteners, and ink raw materials. Fluorescein sodium emits bright green fluorescence under specific light wavelengths.
An organic sodium salt with high water solubility and fluorescence under basic conditions. Sensitive to heat and light, it should be stored in a cool, dark place.
Composed of fluorescein and sodium, belonging to the xanthene family, with a chemical structure that includes three fused rings and a hetero oxygen atom.
Produced by the dehydration-condensation reaction of phthalic anhydride and resorcinol, followed by treatment with sodium hydroxide to form the sodium salt.
*Including some distributors, etc.
Sort by Features
Sort by Area
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Alpha Chemika, founded in 1989 and based in Mumbai, India, is a manufacturer, supplier of laboratory reagents and fine chemicals. Their products are used in multiple industries, including pharmaceutical, chemical, biotechnology, and environmental. Their product portfolio ranges from chemicals such as Silver Nitrate, Perchloric Acid, and Lanthanum Acetate to laboratory tools and equipment such as Air Inlet Tubes, Air Inlet Tubes, and Optical Components. Alpha Chemika has been able to obtain ISO 9001:2000 certification.
Zhengzhou Alfa Chemical Co., Ltd. (ZACC) is a manufacturer of organic chemicals and catalysts established in 2010 and based in Jiaozuo, Henan. The company primarily produces pharmaceutical and organic intermediates as well as photoelectric materials for customers in life science, polymers, dyes, and metallurgy. The company's product lineup includes condensed ring compounds, heterocyclic compounds, COFS/MOFS, and metal catalysts. These supply client corporations such as Bayer AG, Pfizer Inc., and Sumitomo Chemical Company, Ltd. ZACC also offers gram- to ton-level contract synthesis and production services.
Macsen Laboratories is an Indian manufacturer of chemical products that was established as a unit of the NK Agrawal Group in 1952. Based in Udaipur, Rajasthan, the company produces various specialty dyes and biological stains, active pharmaceutical ingredients (APIs), and rare earth mineral compounds. These are used in the manufacture of various commodities including textiles, consumer electronics, and pharmaceuticals. Macsen Laboratories has served several notable clients in a range of industries, including GlaxoSmithKline, Nike, and ArcelorMittal.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Dubi Chem was founded in 1995 and is headquartered in the United Arab Emirates. The company is a marine chemical manufacturer based in Asia, serving marine, oilfield, water treatment, automotive, and shipping industries. The company’s product list includes hundreds of chemicals and finished products, ranging from wheel cleaners to skin care pastes to oil drilling chemicals. The company provides services such as inspections and cleaning specialists who provide dedicated tank cleanings preloading and post-delivery, logistics services, and private labeling options for OEMs and other manufacturers to self-label.
Global Calcium PVT LTD (GCP) is an Indian manufacturer of pharmaceutical components that was established in 1979. Based in Bengaluru, Karnataka, the company produces over 200 different active pharmaceutical ingredients (APIs), mineral actives, and premixed products in different strengths and therapeutic segments such as antipsychotics and vitamins. GCP products are used by clients in various markets including pharmaceuticals, cosmetics, veterinary drugs, and nutraceuticals. The company also provides additional services for customer projects, including contract manufacturing, custom synthesis, and technical support.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Rewine Pharmaceutical, founded in 2014 and headquartered in Surat, Gujarat, India, is a manufacturer, exporter, and supplier of generic and branded finished pharmaceutical formulations. The company's main products are therapeutic medicines, such as those that deal with bacterial infections and fungus. Sample products include anti-bacterial creams, antacids, and anti-fungal solutions. Its product range also includes Himalayan herbal products, allopathic products, and modern pharmaceuticals. The company primarily serves wholesale buyers, exporting the majority of its products to the USA, the UK, and Europe.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Central Drug House |
17.6%
|
| 2 | CFM OSKAR TROPITZSCH GMBH |
11.8%
|
| 3 | Guangzhou Fischer Chemical Co.,Ltd |
8.8%
|
| 4 | Alpha Chemika |
8.8%
|
| 5 | Zhengzhou Alfa Chemical Co.,Ltd |
8.8%
|
| 6 | Macsen Laboratories |
8.8%
|
| 7 | DUBI CHEM MARINE INTERNATIOAL |
8.8%
|
| 8 | Merck |
8.8%
|
| 9 | Rewine Pharmaceutical |
5.9%
|
| 10 | Global Calcium PVT LTD |
5.9%
|
Derivation Method
The ranking is calculated based on the click share within the fluorescein sodium page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
5 | 45.5% |
|
Japan
|
4 | 36.4% |
|
China
|
1 | 9.1% |
Germany
|
1 | 9.1% |
