15 Fluorescein Manufacturers in 2024
This section provides an overview for fluorescein as well as their applications and principles. Also, please take a look at the list of 15 fluorescein manufacturers and their company rankings.
Table of Contents
What Is Fluorescein?
Fluorescein, with the chemical formula C20H12O5 and a molecular weight of 332.31, is a yellowish-red powder. Synthesized by Adolph von Beyer in 1871, it's insoluble in water and slightly soluble in ethanol. This fluorescent dye is known for its bright green fluorescence, making it a valuable tool in various fields.
Uses of Fluorescein
- Bioscience: Used in fluorescence microscopy and cell biology to track the position and movement of objects.
- Medical Diagnostics: Helps detect pathogens and genetic mutations, and is used in angiography in ophthalmology.
- Analytical Chemistry: Employed as chemical sensors and in detecting ammonia in water sources.
Properties of Fluorescein
Fluorescein is highly sensitive to light, with its fluorescence intensity being highest in the pH range of 7-9. It's stable to acids and bases but degrades under prolonged light exposure, requiring light shielding during use and storage.
Structure of Fluorescein
Fluorescein, a xanthene skeleton-based organic compound, exhibits unique optical properties due to its conjugated pi-electron system. It contains hydroxyl groups at the 3- and 6-positions, influencing its water solubility and pH-dependent fluorescence intensity changes.
Other Information on Fluorescein
How Fluorescein Is Produced
Fluorescein synthesis involves reactions like the Friedel-Crafts reaction, using phthalin and resorcinol, and the Wittig Reaction with iodomethane and triphenylphosphine.
List of 15 Fluorescein Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- China
- India
- Japan
- Switzerland
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KANTO CHEMICAL CO.,INC.
Fluorescein
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Junsei Chemical Co.,Ltd.
Fluorescein
Manufacturer Overview
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
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Kishida Chemical Co.,Ltd.
Fluorescein
Manufacturer Overview
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
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XD BIOCHEM LIMITED
Fluorescein
Manufacturer Overview
XD BIOCHEM LIMITED is a manufacturer and supplier of biochemical products that was established in 2010 and is headquartered in Nantong China. The company produces more than 2,000 kinds of biochemical products, including Amino Acids and Derivatives, Antibiotics, Biological Buffers, Coloring Agents, Diagnostic Reagents and, Enzymes and Coenzymes. Its products such as Peptide and Peptide Reagents, Pharma Blocks and Intermediates, Photoelectric Materials, Proteins and Vitamins are utilized by researchers, pharmaceutical companies, and academic institutions for various applications. TXD BIOCHEM LIMITED also provides a range of services, including custom synthesis, contract research, process development, solutions and support.
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Manus Aktteva Biopharma LLP
Fluorescein
Manufacturer Overview
Manus Aktteva Biopharma LLP, established in 2010 and headquartered in Ahmedabad, India, is a manufacturer, supplier, and exporter of pharmaceutical APIs, intermediates, and specialty chemicals. Their wide-ranging products cater to industries such as pharmaceutical, nutraceutical, and biotechnology. They offer Active Pharmaceutical Ingredients (APIs), the fundamental components used in various drug formulations, such as antibiotics, cardiovascular drugs, and anti-inflammatory drugs. The company also supplies specialty chemicals with unique properties applicable to diverse industries, from plastics to cosmetics manufacturing. Furthermore, the company offers custom synthesis services to meet the specific needs of their customers.
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Chemodex Ltd.
Fluorescein
Manufacturer Overview
Chemodex Ltd., established in 2001 and based in St. Gallen, Switzerland, is a manufacturer of fine chemicals, covering different fields such as reagents for life sciences, bioactive molecules, and organic pollutants. The company offers a range of products including fluorescent substances derived from fluorophores such as coumarin, rhodamine, and pyrene. These products are typically used as probes, stains, and in other applications by life-science researchers in academia, biotechnology, and the pharmaceutical industry. Its customer base includes small and medium businesses, large enterprises, as well as academic institutions.
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Merck
Fluorescein
Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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Shubhmets
Fluorescein
Manufacturer Overview
Shubhmets, established in 2004 and situated in Maharashtra, India, is a manufacturer and supplier of pharmaceutical and chemical products. Its extensive range of offerings includes metal powder varieties like Cresol Red and Bromophenol Blue, in addition to fine chemicals, pharmaceutical raw materials (API), pharmaceutical excipients, and precious metal salts. Further enriching their portfolio are nutraceutical products, pharmaceutical formulations, herbal extracts, and nutraceutical formulations. These products cater to various industries, including pharmaceuticals, research, and manufacturing.
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nacalai
Fluorescein
Company Overview
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
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SRL
Fluorescein
Company Overview
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
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Central Drug House
Fluorescein
Company Overview
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
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Paradise Chemical Industries
Fluorescein
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NATIONAL ANALYTICAL CORPORATION
Fluorescein
Distributor Overview
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
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Fluorescein Manufacturer Ranking
*Including some distributors, etc.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
- Kishida Chemical Co.,Ltd.: 283
- Junsei Chemical Co.,Ltd.: 171
Newly Established Company
- NATIONAL ANALYTICAL CORPORATION: 2009 (15 years ago)
- Shubhmets: 2004 (20 years ago)
- Chemodex Ltd.: 2001 (23 years ago)
Company with a History
- nacalai: 1934 (90 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- Junsei Chemical Co.,Ltd.: 1948 (76 years ago)
Fluorescein Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Fluorescein Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
Japan
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4 | 33.3% |
India
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4 | 33.3% |
China
|
2 | 16.7% |
United States of America
|
1 | 8.3% |
Switzerland
|
1 | 8.3% |
