This section provides an overview for pyridoxal as well as their applications and principles. Also, please take a look at the list of 10 pyridoxal manufacturers and their company rankings. Here are the top-ranked pyridoxal companies as of November, 2024: 1.Natural Factors, 2.Natural Healthy Concepts, 3.Bio Basic Inc..
Table of Contents
Pyridoxal, a form of vitamin B6 within the B group vitamins, is identified by the chemical formula C8H9NO3 and has a molecular weight of 167.16. It can be synthesized from pyridoxine through oxidation and hydrolysis processes.
In the human body, pyridoxal is converted to 4-pyridoxic acid by pyridoxal dehydrogenase before being excreted in the urine.
As a crucial vitamin B6 component, pyridoxal participates in numerous biochemical reactions. Its deficiency can lead to skin lesions, glossitis, anemia, and neurological issues, making it vital in medicinal and nutritional applications. Pyridoxal is administered to prevent and treat vitamin B6 deficiency and is essential for individuals with dietary restrictions, such as pregnant and breastfeeding women. Common side effects include rash and digestive issues.
Beyond its medical use, pyridoxal is added to foods and beverages as a fortifying agent and dietary supplement.
Pyridoxal is water-soluble, with its stability and form varying by pH. While stable to heat, it's sensitive to oxidation and alkaline conditions. Absorbed in the small intestine and processed in the liver, pyridoxal plays a role in amino acid metabolism as pyridoxal-5'-phosphate (PLP), a coenzyme for various enzymatic reactions.
Distinctive for its pyridine ring, pyridoxal's structure includes a hydroxy group at the 3-position and an aldehyde group at the 4-position, critical for its coenzyme activity in amino acid metabolism.
Chemically synthesized, common production methods involve the condensation of 5-hydroxynicotinamide and acetone, among others. The choice of method depends on raw material availability and production costs.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Life Extension Foundation is a company that sells dietary supplements, vitamins, and other health products. It is headquartered in Fort Lauderdale, Florida, and was founded in 1981. The company offers a wide array of dietary supplements, vitamins, minerals, and herbal extracts. Its products, such as vitamins, moisturizers, and functional foods are science-backed and help target different health concerns, including weight gain, signs of skin aging, and digestive issues. Life Extension also offers multiple services, such as health information, online doctor consultations, and lab testing. The company's products are available through its website, mail order, and retail stores.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
Hard Eight Nutrition, LLC was founded in 2012 and is headquartered in Henderson, NV, as a manufacturer of nutritional supplements. The containers depict the capacity of the components contained therein, specifying the quantity of servings that can be prepared. The entire range of items the company offers may be conveniently accessed through our online store at BulkSupplements.com, with options accessible in quantities ranging from grams to metric tons. Before distribution, every supplement undergoes testing by an independent laboratory to guarantee the safety of all goods for consumption.
Bio Basic Inc. was established in 2004 and is headquartered in Markham, Ontario and operates as a manufacturer of life science goods and offers laboratory services in molecular biology, cellular biology, microbiology, and biochemistry. The organization holds the belief that laboratory services and consumables need to be accessible at a cheap cost. The company produces genes, oligonucleotides, extraction kits, PCR reagents, and other essential research materials. The integration of manufacturing and supply chain systems allows them to provide competitive pricing within the sector while maintaining high product quality.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Natural Factors |
33.3%
|
2 | Natural Healthy Concepts |
16.7%
|
3 | Bio Basic Inc. |
16.7%
|
4 | Hard Eight Nutrition, LLC |
16.7%
|
5 | Spectrum Chemical Mfg. Corp. |
16.7%
|
Derivation Method
The ranking is calculated based on the click share within the pyridoxal page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
United States of America | 3 | 60.0% |
Japan | 1 | 20.0% |
Switzerland | 1 | 20.0% |