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This section provides an overview for pyridine as well as their applications and principles. Also, please take a look at the list of 13 pyridine manufacturers and their company rankings. Here are the top-ranked pyridine companies as of December, 2024: 1.Actylis, 2.Junsei Chemical Co.,Ltd., 3.Alkali Metals Ltd.
Table of Contents
Pyridine is a heterocyclic compound, often referred to as "azabenzene" due to its structural similarity to benzene, with one carbon atom replaced by a nitrogen atom.
Pyridine is utilized in various applications:
Being a weak base, pyridine acts as a nucleophile in chemical reactions, such as in the acetylation of alcohols with acetic anhydride.
It serves as a raw material for antimicrobial agents like zinc pyrithione and is incorporated into paints and shampoos as an antifouling agent and disinfectant.
Pyridine is a colorless, highly volatile liquid with a distinct odor. It's soluble in water and organic solvents and is toxic to aquatic life. Storage and disposal require careful handling due to its toxicity and environmental impact.
For synthesis, methods like the Hantzsch pyridine synthesis are employed. Removal of pyridine from reaction mixtures can be challenging due to its high boiling point, but techniques such as azeotropic distillation with toluene are used.
While pyridine exhibits aromaticity, its electron density on the aromatic ring is lower than benzene, making it less reactive towards electrophilic substitution but more prone to nucleophilic substitution. Handling pyridine requires awareness of its reactivity and potential hazards, including toxicity and flammability.
*Including some distributors, etc.
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Actylis is based in Port Washington, New York, USA, and is an ISO 13485-certified custom manufacturer of chemical compounds that was established in 1978 as a subsidiary of Aceto. The company mainly produces specialty chemical products for the pharmaceutical, biopharm, and agriscience sectors. These chemical products include cell culture ingredients, active pharmaceutical ingredients (APIs), and buffering salts. It also offers excipients, adenosine for cosmetic ingredients, and vitamins for nutritional supplements. The company operates internationally, with manufacturing facilities in Germany, the United Kingdom, and India. Some of its notable clients include Novartis, Nestlé, and Estée Lauder.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Wego Chemical Group was founded in 1978 and headquartered in Great Neck, New York. WEGO is a full-service supplier and distributor of chemicals, minerals, and other raw materials to clients around the world. Markets and segments include agriculture & animal care, chemical & material manufacturing, construction & building materials, electronics, food & beverage, “household, industrial & institutional”, mining, oil & gas, personal care & pharmaceutical, paper & packaging, surface treatment, textiles, and water treatment.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Alkali Metals Ltd, founded in 1968 and headquartered in Telangana, India, is a manufacturer and supplier of specialty chemicals. Their product portfolio encompasses alkali metal derivatives, pyridine derivatives, tetrazoles, cyclic compounds, and fine chemicals which find applications in pharmaceuticals, agrochemicals, plastics, and dyes production. Additionally, their fine chemicals cater to various sectors, including pharmaceuticals, agrochemicals, and electronics. The company is an ISO 9001 and 14001 certified company following GMP Standards.
A.B. Enterprises was established in 1984 and is headquartered in Maharashtra, India. The company is a manufacturer and supplier of general chemicals, specialties, and industrial chemicals to a broad range of industries including food, textile, plastic, rubber, and other industries. The company exports primarily to Canada, Bahrain, and Dubai. The company’s five major product segments include petrochemicals, food chemicals, laboratory chemicals, water treatment chemicals, and fine chemicals. In addition, the company manufactures dentistry materials, pesticides, and chemical supplies.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Prudence Pharma Chem, established in 2003 with a facility in Bharuch, Gujarat, India, is a manufacturer and developer of pharmaceutical bulk drugs (API) and intermediates. The company products include celecoxib, amlodipine maleate, phenylephrine hydrochloride, sulphonamide, and diketone of celecoxib for pharmaceutical and chemical uses. The firm meets the WHO GMP standards and is ISO 9001:2018 certified. The manufacturing facility is approved as per the Food and Drug Control admonition (FDCA) Gujarat, India.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
KOEI CHEMICAL CO. LTD. established in 1917 and based in Tokyo, Japan, is a manufacturer and supplier specializing in the production of chemical products. The company's product portfolio includes ionic liquids, amines, formalin products, pyridines, and pyrazines. These chemicals are utilized in various sectors, including pharmaceuticals, agricultural chemicals, electronics, furniture manufacturing, and the paint and coatings industry. The company is ISO 9001 and ISO 14001 certified, and provides custom synthesis and technical support to its clients.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Actylis |
22.6%
|
| 2 | Junsei Chemical Co.,Ltd. |
20.8%
|
| 3 | Alkali Metals Ltd |
10.4%
|
| 4 | KOEI CHEMICAL CO., LTD. |
9.4%
|
| 5 | A. B. Enterprises |
7.5%
|
| 6 | nacalai |
7.5%
|
| 7 | Parchem |
6.6%
|
| 8 | MP Biomedicals |
4.7%
|
| 9 | Wego Chemical Group Inc |
4.7%
|
| 10 | Prudence Pharma Chem |
2.8%
|
Derivation Method
The ranking is calculated based on the click share within the pyridine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
4 | 36.4% |
|
Japan
|
4 | 36.4% |
|
India
|
3 | 27.3% |
