This section provides an overview for acetic anhydride as well as their applications and principles. Also, please take a look at the list of 7 acetic anhydride manufacturers and their company rankings. Here are the top-ranked acetic anhydride companies as of November, 2024: 1.Junsei Chemical Co.,Ltd., 2.Jubilant Ingrevia Limited, 3.GJ Chemical.
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Graduated from the University of Tokyo Graduate School in 2012, Master (Engineering). After working as a research fellow (DC1) for Japan Society for the Promotion of Japan, he engaged in basic research at a major chemical manufacturer since April 2014. Specializes in materials science and inorganic chemistry. Japan Ceramics Association, 2020 Technology Encouragement Award.
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・Royal society of ChemistryCrystEngComm (Journal front cover)
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・American chemical SocietyCrystal Growth & Design
https://pubs.acs.org/doi/10.1021/acs.cgd.9b01196
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Acetic anhydride, with the molecular formula C4H6O3 and specific formula (CH3CO)2O, is a colorless liquid. It reacts with water to form acetic acid and has a strong acetic acid odor when exposed to air moisture.
Pure acetic acid and glacial acetic acid, which have low water content, differ from acetic anhydride. Acetic anhydride is the simplest carboxylic anhydride to isolate and is a key raw material in organic synthesis, forming esters with alcohols and cellulose.
Acetic anhydride has a higher boiling point (139.8°C) than acetic acid (118°C) and can cause irritation and tearing when inhaled or if it contacts the skin. It should be handled with care, especially when heated.
Acetic anhydride hydrolyzes to form acetic acid, fully miscible in water:
(CH3CO)2O + H2O → 2 CH3COOH
First synthesized in 1852 by Charles Frédéric Gerhardt, acetic anhydride is now industrially produced by reacting ketene with acetic acid, or through the carbonylation of methyl acetate.
H2C=C=O + CH3COOH → (CH3CO)2O
CH3CO2CH3 + CO → (CH3CO)2O
Acetic anhydride is essential for acetylation in organic chemistry, introducing acetyl groups into various compounds.
Reacting with alcohols, it forms acetic esters (e.g., ethyl acetate from ethanol), and with cellulose, it yields acetyl cellulose used in a range of applications including cigarette filters and synthetic fibers.
(CH3CO)2O + CH3CH2OH → CH3CO2CH2CH3 + CH3COOH
Acetic anhydride acetylates aromatic rings in the presence of an acid catalyst, as seen in the conversion of ferrocene to acetylferrocene.
(C5H5)2Fe + (CH3CO)2O → (C5H5)Fe(C5H4COCH3) + CH3COOH
Acetic anhydride is also used to convert dicarboxylic acids into their corresponding anhydrides.
Additionally, acetic anhydride's applications have expanded into new areas like polarizer protection film for LCDs, liquid crystal polymers, and urethane elastic fibers.
*Including some distributors, etc.
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G.J. Chemical is a family-owned company based in Newark, New Jersey. G.J. Chemical serves chemical distributors, laboratories, and a variety of end users with high purity chemical products and custom services. G.J. Chemical capabilities include testing, bulk storage, custom blending, liquid bulk handling, and purifying. G.J. Chemical’s chemical products include reagents, acrylate monomers, hand sanitizers, and isopropyl alcohol. These are made to USP, FCC, Reagent ACS, military grade, and other standards.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Celanese is an American manufacturer of chemicals and specialty materials. The company was originally founded in 1918 as the American Cellulose and Chemical Manufacturing Company before its rebrand in 1927. Based in Irving, Texas, the company produces natural polymers such as cellulose acetate and intermediate chemicals like acetyl chain, as well as food ingredients including sorbates and engineered materials comprising of Riteflex® thermoplastic polyester elastomers. These are utilized in the industrial processes of various sectors, including food and beverages, and energy production. Celanese has served several large corporations operating internationally, including the Coca-Cola Company, Shell Plc, and the L’Oreal cosmetics company.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Jubilant Ingrevia Limited, established in 2019, is headquartered in Uttar Pradesh, India and operates as a manufacturer and supplier of life science goods and solutions, catering to pharmaceutical, nutritional, agrochemical, and industrial sectors. The company provides a diverse selection of premium ingredients utilized across various sectors. The company's offering also includes specialized development and manufacturing services exclusively tailored to pharmaceutical and agrochemical clients. The organization is motivated by the objective of enhancing the quality of life for a large number of individuals via the implementation of ground-breaking solutions and advanced technology.
Eastman Chemical was founded in 1920 and is headquartered in Kingsport, Tennessee. The company is a manufacturer and distributor of specialty chemicals, including coatings, adhesives, fibers, and plastics for industries such as automotive, medical, manufacturing, and construction. The company operates through four segments: Additives & Functional Products, Advanced Materials, Chemical Intermediates, and Fibers segments. Additives & Functional Products include food and fertilizer-based products. Advanced Materials include films and other chemicals used in transportation and electronics. Chemicals include phthalate plasticizers and other plastic products. Fibers include cigarette filters and other products.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Junsei Chemical Co.,Ltd. |
28.7%
|
2 | Jubilant Ingrevia Limited |
16.0%
|
3 | GJ Chemical |
12.7%
|
4 | Eastman Chemical Co. |
11.6%
|
5 | KANTO CHEMICAL CO.,INC. |
11.6%
|
6 | Celanese |
11.0%
|
7 | nacalai |
8.3%
|
Derivation Method
The ranking is calculated based on the click share within the acetic anhydride page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 3 | 60.0% |
United States of America | 1 | 20.0% |
India | 1 | 20.0% |